7MAB
HIV-1 Protease (I84V) in Complex with GS-8374
Summary for 7MAB
Entry DOI | 10.2210/pdb7mab/pdb |
Descriptor | Protease, SULFATE ION, DIETHYL ({4-[(2S,3R)-2-({[(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YLOXY]CARBONYL}AMINO)-3-HYDROXY-4-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}BUTYL]PHENOXY}METHYL)PHOSPHONATE, ... (4 entities in total) |
Functional Keywords | hiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human immunodeficiency virus 1 (HIV-1) |
Total number of polymer chains | 2 |
Total formula weight | 22844.72 |
Authors | Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-04-27, Last modification date: 2023-10-18) |
Primary citation | Lockbaum, G.J.,Schiffer, C.A. HIV-1 Protease (I84V) in Complex with GS-8374 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.879 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)