7N6T

Crystal structure of inhibitor-free HIV-1 PRS17 revertant mutant PRS17 V48G

Summary for 7N6T

Entry DOI	10.2210/pdb7n6t/pdb
Related	5T2E 5T2Z 6O54 6O57 6O5A 6O5X
Descriptor	Protease (2 entities in total)
Functional Keywords	hiv-1 protease, drug resistance, prs17, hydrolase
Biological source	Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1)
Total number of polymer chains	2
Total formula weight	21501.13
Authors	Burnaman, S.H.,Wang, Y.-F.,Weber, I.T. (deposition date: 2021-06-09, release date: 2021-09-08, Last modification date: 2023-10-18)
Primary citation	Burnaman, S.H.,Kneller, D.W.,Wang, Y.F.,Kovalevsky, A.,Weber, I.T. Revertant mutation V48G alters conformational dynamics of highly drug resistant HIV protease PRS17. J.Mol.Graph.Model., 108:108005-108005, 2021 Cited by PubMed: 34419931 DOI: 10.1016/j.jmgm.2021.108005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.32 Å)

Structure validation