5T2E
Crystal Structure of multi-drug resistant HIV-1 protease PR-S17
Summary for 5T2E
| Entry DOI | 10.2210/pdb5t2e/pdb |
| Related | 5T2Z |
| Descriptor | Protease, CHLORIDE ION (3 entities in total) |
| Functional Keywords | protease, hydrolase |
| Biological source | Human immunodeficiency virus 1 |
| Total number of polymer chains | 1 |
| Total formula weight | 11004.31 |
| Authors | Agniswamy, J.,Weber, I.T. (deposition date: 2016-08-23, release date: 2017-01-11, Last modification date: 2023-10-04) |
| Primary citation | Agniswamy, J.,Louis, J.M.,Roche, J.,Harrison, R.W.,Weber, I.T. Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics. PLoS ONE, 11:e0168616-e0168616, 2016 Cited by PubMed: 27992544DOI: 10.1371/journal.pone.0168616 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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