7M9Z

HIV-1 Protease (I84V) in Complex with TMC-126

Summary for 7M9Z

• Entry DOI: 10.2210/pdb7m9z/pdb
• Descriptor: Protease, SULFATE ION, (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL [(1S,2R)-1-BENZYL-2-HYDROXY-3-{ISOBUTYL[(4-METHOXYPHENYL)SULFONYL]AMINO}PROPYL]CARBAMATE, ... (4 entities in total)
• Functional Keywords: hiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Total number of polymer chains: 2
• Total formula weight: 22870.73

Authors

Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-04-27, Last modification date: 2023-10-18)

• Primary citation: Lockbaum, G.J.,Schiffer, C.A.; HIV-1 Protease (I84V) in Complex with TMC-126; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.828 Å)