PDB: 2624 resultsInfo pagesStatus searchChemie searchBIRD

---

6FKO	Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, hadacidin at 2.1 Angstrom resolution Descriptor: 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Adenylosuccinate synthetase, ... Authors: Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A. Deposit date: 2018-01-24 Release date: 2019-06-26 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP, dGMP, HAdacidin at 2.1 Angstrom resolution To Be Published
2HRY	T. maritima PurL complexed with AMPPCP Descriptor: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... Authors: Ealick, S.E, Morar, M. Deposit date: 2006-07-20 Release date: 2007-01-09 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily Biochemistry, 45, 2006
1M0T	Yeast Glutathione Synthase Descriptor: SULFATE ION, glutathione synthetase Authors: Gogos, A, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2002-06-14 Release date: 2002-12-11 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Large Conformational Changes in the Catalytic Cycle of Glutathione Synthase Structure, 10, 2002
3E60	Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae Descriptor: 3-oxoacyl-[acyl-carrier-protein ] synthase II, POTASSIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2008-08-14 Release date: 2008-08-26 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae To be Published
2HS4	T. maritima PurL complexed with FGAR and AMPPCP Descriptor: MAGNESIUM ION, N-(N-FORMYLGLYCYL)-5-O-PHOSPHONO-BETA-D-RIBOFURANOSYLAMINE, PHOSPHATE ION, ... Authors: Ealick, S.E, Morar, M. Deposit date: 2006-07-21 Release date: 2007-01-09 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily Biochemistry, 45, 2006
2HS3	T. maritima PurL complexed with FGAR Descriptor: N-(N-FORMYLGLYCYL)-5-O-PHOSPHONO-BETA-D-RIBOFURANOSYLAMINE, PHOSPHATE ION, Phosphoribosylformylglycinamidine synthase II Authors: Ealick, S.E, Morar, M. Deposit date: 2006-07-21 Release date: 2007-01-09 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily Biochemistry, 45, 2006
2HRU	T. maritima PurL complexed with ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase II Authors: Ealick, S.E, Morar, M. Deposit date: 2006-07-20 Release date: 2007-01-09 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Complexed Structures of Formylglycinamide Ribonucleotide Amidotransferase from Thermotoga maritima Describe a Novel ATP Binding Protein Superfamily Biochemistry, 45, 2006
6NOP	Structure of Cyanothece McdA(D38A)-ATP complex Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION Authors: Schumacher, M.A. Deposit date: 2019-01-16 Release date: 2019-04-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs. Nucleic Acids Res., 47, 2019
5T8T	Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound AMP and Magnesium Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, S-adenosylmethionine synthase Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2016-09-08 Release date: 2016-09-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal Structure of a S-adenosylmethionine Synthase from Neisseria gonorrhoeae with bound AMP and Magnesium to be published
6K5V	Structure of CSY4 Apo-form Descriptor: CHLORIDE ION, Citrate synthase 4, mitochondrial Authors: Nishio, K, Mizushima, T. Deposit date: 2019-05-31 Release date: 2020-03-18 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.69 Å) Cite: Structural and biochemical characterization of mitochondrial citrate synthase 4 from Arabidopsis thaliana. Acta Crystallogr.,Sect.F, 76, 2020
4ACD	GSK3b in complex with inhibitor Descriptor: 3-AMINO-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA Authors: Xue, Y, Ormo, M. Deposit date: 2011-12-15 Release date: 2012-05-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
4ACH	GSK3b in complex with inhibitor Descriptor: 3-AMINO-N-(3-METHOXYPROPYL)-6-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}PYRAZINE-2-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA Authors: Xue, Y, Ormo, M. Deposit date: 2011-12-15 Release date: 2012-05-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
5HLP	X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH BRD3937 Descriptor: 4-(2-methoxyphenyl)-3,7,7-trimethyl-1,6,7,8-tetrahydro-5H-pyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta Authors: White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K. Deposit date: 2016-01-15 Release date: 2016-05-25 Last modified: 2016-07-27 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. Acs Chem.Biol., 11, 2016
4ACG	GSK3b in complex with inhibitor Descriptor: 2-AMINO-5-{4-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-N-[4-(PYRROLIDIN-1-YLMETHYL)PYRIDIN-3-YL]PYRIDINE-3-CARBOXAMIDE, GLYCOGEN SYNTHASE KINASE-3 BETA Authors: Xue, Y, Ormo, M. Deposit date: 2011-12-15 Release date: 2012-05-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
4ACC	GSK3b in complex with inhibitor Descriptor: 3-AMINO-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}PHENYL)-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, DIMETHYL SULFOXIDE, GLYCOGEN SYNTHASE KINASE-3 BETA Authors: Xue, Y, Ormo, M. Deposit date: 2011-12-14 Release date: 2012-05-16 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines. J. Med. Chem., 55, 2012
5HLN	X-RAY CRYSTAL STRUCTURE OF GSK3B IN COMPLEX WITH CHIR99021 Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHIR99021, Glycogen synthase kinase-3 beta, ... Authors: White, A, Lakshminarasimhan, D, Nadupalli, A, Suto, R.K. Deposit date: 2016-01-15 Release date: 2016-05-25 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. Acs Chem.Biol., 11, 2016
6PK4	cryoEM structure of the substrate-bound human CTP synthase 2 filament Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CTP synthase 2, URIDINE 5'-TRIPHOSPHATE Authors: Lynch, E.M, Kollman, J.M. Deposit date: 2019-06-28 Release date: 2019-12-25 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Coupled structural transitions enable highly cooperative regulation of human CTPS2 filaments. Nat.Struct.Mol.Biol., 27, 2020
3ETH	Crystal structure of E. coli Purk in complex with MgATP Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylaminoimidazole carboxylase ATPase subunit Authors: Holden, H.M, Thoden, J.B. Deposit date: 2008-10-08 Release date: 2008-10-21 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Structural analysis of the active site geometry of N(5)-Carboxyaminoimidazole ribonucleotide synthetase from Escherichia coli. Biochemistry, 47, 2008
3SAY	Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142 Descriptor: (3Z)-N,N-diethyl-3-[(3E)-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide, (4S)-2-METHYL-2,4-PENTANEDIOL, FORMIC ACID, ... Authors: Mazanetz, M.P, Cheng, R.K.Y, Rowan, F, Laughton, C.A, Barker, J.J, Fischer, P.M. Deposit date: 2011-06-03 Release date: 2012-06-13 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.231 Å) Cite: Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142 To be Published
7UTT	Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination Descriptor: Cyclic GMP-AMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION, ... Authors: Wu, S, Gabelli, S.B, Sohn, J. Deposit date: 2022-04-27 Release date: 2023-05-03 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination To Be Published
7WAF	Trichodesmium erythraeum cyanophycin synthetase 1 (TeCphA1) with ATPgammaS and 4x(beta-Asp-Arg) Descriptor: 4x(beta-Asp-Arg), ARGININE, Cyanophycin synthase, ... Authors: Miyakawa, T, Yang, J, Kawasaki, M, Adachi, N, Fujii, A, Miyauchi, Y, Muramatsu, T, Moriya, T, Senda, T, Tanokura, M. Deposit date: 2021-12-14 Release date: 2022-09-07 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.52 Å) Cite: Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase. Nat Commun, 13, 2022
7WAD	Trichodesmium erythraeum cyanophycin synthetase 1 (TeCphA1) with ATPgammaS Descriptor: Cyanophycin synthase, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER Authors: Kawasaki, M, Miyakawa, T, Yang, J, Adachi, N, Fujii, A, Miyauchi, Y, Muramatsu, T, Moriya, T, Senda, T, Tanokura, M. Deposit date: 2021-12-14 Release date: 2022-09-07 Last modified: 2024-06-26 Method: ELECTRON MICROSCOPY (2.96 Å) Cite: Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase. Nat Commun, 13, 2022
7WAE	Trichodesmium erythraeum cyanophycin synthetase 1 (TeCphA1) with ATPgammaS, 4x(beta-Asp-Arg), and aspartate Descriptor: 4x(beta-Asp-Arg), ARGININE, ASPARTIC ACID, ... Authors: Miyakawa, T, Yang, J, Kawasaki, M, Adachi, N, Fujii, A, Miyauchi, Y, Muramatsu, T, Moriya, T, Senda, T, Tanokura, M. Deposit date: 2021-12-14 Release date: 2022-09-07 Last modified: 2022-09-14 Method: ELECTRON MICROSCOPY (2.64 Å) Cite: Structural bases for aspartate recognition and polymerization efficiency of cyanobacterial cyanophycin synthetase. Nat Commun, 13, 2022
3GB2	GSK3beta inhibitor complex Descriptor: 2-methyl-5-(3-{4-[(S)-methylsulfinyl]phenyl}-1-benzofuran-5-yl)-1,3,4-oxadiazole, Glycogen synthase kinase-3 beta Authors: Mol, C.D. Deposit date: 2009-02-18 Release date: 2010-03-02 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.4 Å) Cite: 2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta with good brain permeability. J.Med.Chem., 52, 2009
4M9U	The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 Descriptor: ACETATE ION, CHLORIDE ION, FORMIC ACID, ... Authors: Tan, K, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2013-08-15 Release date: 2013-08-28 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.599 Å) Cite: The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 To be Published

<30313233343536373839404142434445>