8SZD
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![BU of 8szd by Molmil](/molmil-images/mine/8szd) | Crystal structure of Yersinia pestis dihydrofolate reductase at 1.25-A resolution | Descriptor: | CHLORIDE ION, Dihydrofolate reductase, MAGNESIUM ION, ... | Authors: | Shaw, G.X, Cherry, S, Tropea, J.E, Waugh, D.S, Ji, X. | Deposit date: | 2023-05-29 | Release date: | 2023-06-07 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal structure of Yersinia pestis dihydrofolate reductase at 1.25-A resolution To be published
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2YT9
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![BU of 2yt9 by Molmil](/molmil-images/mine/2yt9) | Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278 | Descriptor: | ZINC ION, zinc finger-containing protein 1 | Authors: | Kasahara, N, Tsuda, K, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of C2H2 type Zinc finger domain 345 in Zinc finger protein 278 To be Published
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5E12
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2YTS
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![BU of 2yts by Molmil](/molmil-images/mine/2yts) | Solution structure of the C2H2 type zinc finger (region 715-747) of human Zinc finger protein 484 | Descriptor: | ZINC ION, Zinc finger protein 484 | Authors: | Tochio, N, Tomizawa, T, Abe, H, Saito, K, Li, H, Sato, M, Koshiba, S, Kobayashi, N, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the C2H2 type zinc finger (region 715-747) of human Zinc finger protein 484 To be Published
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2YU7
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![BU of 2yu7 by Molmil](/molmil-images/mine/2yu7) | Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A | Descriptor: | Tyrosine-protein phosphatase non-receptor type 6, natural killer group 2A | Authors: | Kasai, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-05 | Release date: | 2008-04-15 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A To be Published
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8T1A
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5E1C
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![BU of 5e1c by Molmil](/molmil-images/mine/5e1c) | Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative dimethyl {(1S)-3-[bis(4-hydroxyphenyl)methylidene]cyclohexyl}propanedioate | Descriptor: | Estrogen receptor, Nuclear receptor coactivator 2, dimethyl {(1S)-3-[bis(4-hydroxyphenyl)methylidene]cyclohexyl}propanedioate | Authors: | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | Deposit date: | 2015-09-29 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
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5DRR
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![BU of 5drr by Molmil](/molmil-images/mine/5drr) | Crystal structure of the Pseudomonas aeruginosa LpxC/LPC-058 complex | Descriptor: | 4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]-N-[(2S,3S)-4,4-difluoro-3-hydroxy-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]benzamide, NITRATE ION, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ... | Authors: | Lee, C.-J, Najeeb, J, Zhou, P. | Deposit date: | 2015-09-16 | Release date: | 2016-03-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Drug design from the cryptic inhibitor envelope. Nat Commun, 7, 2016
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2YKM
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![BU of 2ykm by Molmil](/molmil-images/mine/2ykm) | Crystal structure of HIV-1 Reverse Transcriptase (RT) in complex with a Difluoromethylbenzoxazole (DFMB) Pyrimidine Thioether derivative, a non-nucleoside RT inhibitor (NNRTI) | Descriptor: | 2-[DIFLUORO-[(4-METHYL-PYRIMIDINYL)-THIO]METHYL]-BENZOXAZOLE, CALCIUM ION, REVERSE TRANSCRIPTASE/RIBONUCLEASE H | Authors: | Boyer, J, Arnoult, E, Medebielle, M, Guillemont, J, Unge, T, Unge, J, Jochmans, D. | Deposit date: | 2011-05-28 | Release date: | 2011-08-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Difluoromethylbenzoxazole Pyrimidine Thioether Derivatives: A Novel Class of Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors. J.Med.Chem., 54, 2011
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8SUG
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2YUP
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![BU of 2yup by Molmil](/molmil-images/mine/2yup) | Solution structure of the second SH3 domain of human Vinexin | Descriptor: | Vinexin | Authors: | Abe, H, Tochio, N, Miyamoto, K, Saito, K, Sasagawa, A, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-06 | Release date: | 2007-10-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the second SH3 domain of human Vinexin To be Published
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2Y7K
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![BU of 2y7k by Molmil](/molmil-images/mine/2y7k) | DntR Inducer Binding Domain in Complex with Salicylate. Monoclinic crystal form | Descriptor: | 2-HYDROXYBENZOIC ACID, LYSR-TYPE REGULATORY PROTEIN | Authors: | Devesse, L, Smirnova, I, Lonneborg, R, Kapp, U, Brzezinski, P, Leonard, G.A, Dian, C. | Deposit date: | 2011-01-31 | Release date: | 2011-07-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structures of Dntr Inducer Binding Domains in Complex with Salicylate Offer Insights Into the Activation of Lysr-Type Transcriptional Regulators. Mol.Microbiol., 81, 2011
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2GF3
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![BU of 2gf3 by Molmil](/molmil-images/mine/2gf3) | Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution. | Descriptor: | 2-FUROIC ACID, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Chen, Z, Trickey, P, Jorns, M.S, Mathews, F.S. | Deposit date: | 2006-03-21 | Release date: | 2007-02-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of the complex of monomeric sarcosine with its substrate analogue inhibitor 2-furoic acid at 1.3 A resolution. TO BE PUBLISHED
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2YV9
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8SZB
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8T7Z
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2Y6V
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2YIX
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![BU of 2yix by Molmil](/molmil-images/mine/2yix) | Triazolopyridine Inhibitors of p38 | Descriptor: | 1-ethyl-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea, MITOGEN-ACTIVATED PROTEIN KINASE 14 | Authors: | Millan, D.S, Anderson, M, Bunnage, M.E, Burrows, J.L, Butcher, K.J, Dodd, P.G, Evans, T.J, Fairman, D.A, Han, s, Hughes, S.J, Irving, S.L, Kilty, I.C, Lemaitre, A, Lewthawaite, R.A, Mahke, A, Marr, E, Mathias, J.P, Philip, J, Phillips, C, Smith, R.T, Stefaniak, M.H, Yeadon, M. | Deposit date: | 2011-05-17 | Release date: | 2011-11-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease. J.Med.Chem., 54, 2011
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8SQZ
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8ST7
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![BU of 8st7 by Molmil](/molmil-images/mine/8st7) | Structure of E3 ligase VsHECT bound to ubiquitin | Descriptor: | E3 ubiquitin-protein ligase SopA-like catalytic domain-containing protein, Ubiquitin, prop-2-en-1-amine | Authors: | Franklin, T.G, Pruneda, J.N. | Deposit date: | 2023-05-09 | Release date: | 2023-07-12 | Last modified: | 2024-01-03 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Bacterial ligases reveal fundamental principles of polyubiquitin specificity. Mol.Cell, 83, 2023
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2YMA
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![BU of 2yma by Molmil](/molmil-images/mine/2yma) | X-ray structure of the Yos9 dimerization domain | Descriptor: | PROTEIN OS-9 HOMOLOG | Authors: | Hanna, J, Schuetz, A, Zimmermann, F, Behlke, J, Sommer, T, Heinemann, U. | Deposit date: | 2011-06-07 | Release date: | 2012-01-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.545 Å) | Cite: | Structural and Biochemical Basis of Yos9 Protein Dimerization and Possible Contribution to Self-Association of 3-Hydroxy-3-Methylglutaryl-Coenzyme a Reductase Degradation Ubiquitin-Ligase Complex. J.Biol.Chem., 287, 2012
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2YMV
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![BU of 2ymv by Molmil](/molmil-images/mine/2ymv) | Structure of Reduced M Smegmatis 5246, a homologue of M.Tuberculosis Acg | Descriptor: | 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, ACETATE ION, ACG NITROREDUCTASE, ... | Authors: | Chauviac, F.-X, Bommer, M, Dobbek, H, Keep, N.H. | Deposit date: | 2012-10-10 | Release date: | 2012-11-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Reduced Msacg, a Putative Nitroreductase from Mycobacterium Smegmatis and a Close Homologue of Mycobacterium Tuberculosis Acg. J.Biol.Chem., 287, 2012
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8ST9
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2G88
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![BU of 2g88 by Molmil](/molmil-images/mine/2g88) | MSRECA-dATP COMPLEX | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CITRIC ACID, MAGNESIUM ION, ... | Authors: | Krishna, R, Manjunath, G.P, Kumar, P, Surolia, A, Chandra, N.R, Muniyappa, K, Vijayan, M. | Deposit date: | 2006-03-02 | Release date: | 2006-05-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery. Nucleic Acids Res., 34, 2006
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2GI7
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![BU of 2gi7 by Molmil](/molmil-images/mine/2gi7) | Crystal structure of human platelet Glycoprotein VI (GPVI) | Descriptor: | CHLORIDE ION, GLYCEROL, GPVI protein, ... | Authors: | Horii, K, Kahn, M.L, Herr, A.B. | Deposit date: | 2006-03-28 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI. Blood, 108, 2006
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