PDB: 98078 resultsInfo pagesStatus searchChemie searchBIRD

---

5MRQ	Arabidopsis thaliana IspD Asp262Ala Mutant Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic, ... Authors: Schwab, A, Illarionov, B, Frank, A, Kunfermann, A, Seet, M, Bacher, A, Witschel, M, Fischer, M, Groll, M, Diederich, F. Deposit date: 2016-12-23 Release date: 2017-07-19 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Mechanism of Allosteric Inhibition of the Enzyme IspD by Three Different Classes of Ligands. ACS Chem. Biol., 12, 2017
5JGS	Human carbonic anhydrase II (F131Y/L198A) complexed with benzo[d]thiazole-2-sulfonamide Descriptor: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION Authors: Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M. Deposit date: 2016-04-20 Release date: 2017-01-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.11 Å) Cite: Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl., 56, 2017
3QS7	Crystal structure of a human Flt3 ligand-receptor ternary complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FL cytokine receptor, SL cytokine Authors: Verstraete, K, Savvides, S.N. Deposit date: 2011-02-19 Release date: 2011-03-16 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (4.3 Å) Cite: Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex. Blood, 118, 2011
5O6S	UbV.B4R, a dimeric ubiquitin variant binding to BIRC4 RING Descriptor: Polyubiquitin-B Authors: Gabrielsen, M, Buetow, L, Huang, D.T. Deposit date: 2017-06-07 Release date: 2017-11-01 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.9 Å) Cite: A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants. Mol. Cell, 68, 2017
2HCH	N-Domain Of Grp94 In Complex With the Novel Ligand N-(2-amino)ethyl Carboxyamido Adenosine Descriptor: 5'-N-[(2-AMINO)ETHYL CARBOXAMIDO] ADENOSINE, Endoplasmin, PENTAETHYLENE GLYCOL, ... Authors: Immormino, R.M, Gewirth, D.T. Deposit date: 2006-06-16 Release date: 2007-05-01 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: N-Domain Of Grp94 In Complex With the Novel Ligand N-aminoethyl Carboxyamido Adenosine To be Published
5JDV	Human carbonic anhydrase II (F131W) complexed with benzo[d]thiazole-2-sulfonamide Descriptor: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION Authors: Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M. Deposit date: 2016-04-17 Release date: 2017-01-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl., 56, 2017
2REG	ABC-transporter choline binding protein in complex with choline Descriptor: CHOLINE ION, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN Authors: Oswald, C, Schimtt, L, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Bremer, E. Deposit date: 2007-09-26 Release date: 2008-09-16 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states. J.Biol.Chem., 283, 2008
5JEH	Human carbonic anhydrase II (L198A) complexed with benzo[d]thiazole-2-sulfonamide Descriptor: 1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION Authors: Fox, J.M, Kang, K, Sastry, M, Sherman, W, Sankaran, B, Zwart, P.H, Whitesides, G.M. Deposit date: 2016-04-18 Release date: 2017-01-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (1.13 Å) Cite: Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase. Angew. Chem. Int. Ed. Engl., 56, 2017
2YME	Crystal structure of a mutant binding protein (5HTBP-AChBP) in complex with granisetron Descriptor: 1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... Authors: Kesters, D, Thompson, A.J, Brams, M, Elk, R.v, Spurny, R, Geitmann, M, Villalgordo, J.M, Guskov, A, Danielson, U.H, Lummis, S.C.R, Smit, A.B, Ulens, C. Deposit date: 2012-10-09 Release date: 2012-12-26 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Basis of Ligand Recognition in 5-Ht3 Receptors. Embo Rep., 14, 2013
1IXQ	Enzyme-Phosphate2 Complex of Pyridoxine 5'-Phosphate synthase Descriptor: PHOSPHATE ION, Pyridoxine 5'-phosphate Synthase Authors: Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. Deposit date: 2002-06-28 Release date: 2003-02-11 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
4P0I	Structure of the PBP NocT Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Nopaline-binding periplasmic protein Authors: Vigouroux, A, Morera, S. Deposit date: 2014-02-21 Release date: 2014-10-22 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Agrobacterium uses a unique ligand-binding mode for trapping opines and acquiring a competitive advantage in the niche construction on plant host. Plos Pathog., 10, 2014
4GX2	GsuK channel bound to NAD Descriptor: CALCIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... Authors: Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. Deposit date: 2012-09-03 Release date: 2012-12-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
3MNO	Crystal structure of the agonist form of mouse glucocorticoid receptor stabilized by (A611V, F608S) mutations at 1.55A Descriptor: DEXAMETHASONE, GLYCEROL, Glucocorticoid receptor, ... Authors: Schoch, G.A, Seitz, T, Benz, J, Banner, D, Stihle, M, D'Arcy, B, Thoma, R, Sterner, R, Hennig, M, Ruf, A. Deposit date: 2010-04-22 Release date: 2010-09-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Enhancing the stability and solubility of the glucocorticoid receptor ligand-binding domain by high-throughput library screening. J.Mol.Biol., 403, 2010
1JBM	Heptameric crystal structure of Mth649, an Sm-like archaeal protein from Methanobacterium thermautotrophicum Descriptor: 1,2-ETHANEDIOL, ACETIC ACID, PUTATIVE SNRNP SM-LIKE PROTEIN Authors: Mura, C, Eisenberg, D. Deposit date: 2001-06-06 Release date: 2003-03-25 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.85 Å) Cite: The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs) Protein Sci., 12, 2003
3OUV	SeMet Derivative of L512M mutant of PASTA domain 3 of Mycobacterium tuberculosis PknB Descriptor: Serine/threonine protein kinase Authors: Prigozhin, D.M, Chen, T.Y, Alber, T. Deposit date: 2010-09-15 Release date: 2011-09-21 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.004 Å) Cite: Structural and Genetic Analyses of the Mycobacterium tuberculosis Protein Kinase B Sensor Domain Identify a Potential Ligand-binding Site. J.Biol.Chem., 291, 2016
1JF3	Crystal Structure Of Component III Glycera Dibranchiata Monomeric Hemoglobin Descriptor: PROTOPORPHYRIN IX CONTAINING FE, monomer hemoglobin component III Authors: Park, H.J, Yang, C, Treff, N, Satterlee, J.D, Kang, C.H. Deposit date: 2001-06-20 Release date: 2002-06-20 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal Structures of Unligated and CN-Ligated Glycera dibranchiata Monomer Ferric Hemoglobin Components III and IV Proteins, 49, 2002
3GRU	Crystal Structure of the Complex between AMP and Methanocaldococcus jannaschi Dim1 Descriptor: ADENOSINE MONOPHOSPHATE, Dimethyladenosine transferase, SULFATE ION Authors: Scarsdale, J.N, Musayev, F.N, Rife, J.P. Deposit date: 2009-03-26 Release date: 2010-03-31 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design. Biochemistry, 49, 2010
5B82	Crystal structure of the cyanobacterial heme-protein Tll0287 Descriptor: CHLORIDE ION, HEME C, Tll0287 protein Authors: Suga, M, Motomura, T, Shen, J.R. Deposit date: 2016-06-12 Release date: 2017-05-03 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure and redox properties of a novel cyanobacterial heme protein with a His/Cys heme axial ligation and a Per-Arnt-Sim (PAS)-like domain J. Biol. Chem., 292, 2017
1JF4	Crystal Structure Of Component IV Glycera Dibranchiata Monomeric Hemoglobin Descriptor: PROTOPORPHYRIN IX CONTAINING FE, monomer hemoglobin component IV Authors: Park, H.J, Yang, C, Treff, N, Satterlee, J.D, Kang, C.H. Deposit date: 2001-06-20 Release date: 2002-06-20 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal Structures of Unligated and CN-Ligated Glycera dibranchiata Monomer Ferric Hemoglobin Components III and IV Proteins, 49, 2002
4GX1	Crystal structure of the GsuK bound to ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, PHOSPHATE ION, ... Authors: Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. Deposit date: 2012-09-03 Release date: 2012-12-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012
3NY1	Structure of the ubr-box of the UBR1 ubiquitin ligase Descriptor: E3 ubiquitin-protein ligase UBR1, ZINC ION Authors: Matta-Camacho, E, Kozlov, G, Li, F, Gehring, K. Deposit date: 2010-07-14 Release date: 2010-08-11 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.085 Å) Cite: Structural basis of substrate recognition and specificity in the N-end rule pathway. Nat.Struct.Mol.Biol., 17, 2010
1IXO	Enzyme-analogue substrate complex of Pyridoxine 5'-Phosphate Synthase Descriptor: Pyridoxine 5'-Phosphate synthase, SN-GLYCEROL-3-PHOSPHATE Authors: Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. Deposit date: 2002-06-28 Release date: 2003-02-11 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
2RIN	ABC-transporter choline binding protein in complex with acetylcholine Descriptor: ACETYLCHOLINE, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN Authors: Oswald, C, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Le Rudulier, D, Schmitt, L, Bremer, E. Deposit date: 2007-10-12 Release date: 2008-09-30 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states. J.Biol.Chem., 283, 2008
2CT2	Solution Structure of the RING domain of the Tripartite motif protein 32 Descriptor: Tripartite motif protein 32, ZINC ION Authors: Miyamoto, K, Tochio, N, Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-23 Release date: 2005-11-23 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution Structure of the RING domain of the Tripartite motif protein 32 To be Published
4GX0	Crystal structure of the GsuK L97D mutant Descriptor: CALCIUM ION, PHOSPHATE ION, POTASSIUM ION, ... Authors: Kong, C, Zeng, W, Ye, S, Chen, L, Sauer, D.B, Lam, Y, Derebe, M.G, Jiang, Y. Deposit date: 2012-09-03 Release date: 2012-12-26 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.601 Å) Cite: Distinct gating mechanisms revealed by the structures of a multi-ligand gated K(+) channel. elife, 1, 2012

<335336337338339340341342343344345346347348349350>