5MRQ

Arabidopsis thaliana IspD Asp262Ala Mutant

Summary for 5MRQ

Entry DOI	10.2210/pdb5mrq/pdb
Related	1W77 2YC5 4NAK
Descriptor	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, ... (4 entities in total)
Functional Keywords	herbicide, anti-infectives, drug discovery, mutant, transferase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Cellular location	Plastid, chloroplast stroma : P69834
Total number of polymer chains	1
Total formula weight	25957.97
Authors	Schwab, A.,Illarionov, B.,Frank, A.,Kunfermann, A.,Seet, M.,Bacher, A.,Witschel, M.,Fischer, M.,Groll, M.,Diederich, F. (deposition date: 2016-12-23, release date: 2017-07-19, Last modification date: 2024-01-17)
Primary citation	Schwab, A.,Illarionov, B.,Frank, A.,Kunfermann, A.,Seet, M.,Bacher, A.,Witschel, M.C.,Fischer, M.,Groll, M.,Diederich, F. Mechanism of Allosteric Inhibition of the Enzyme IspD by Three Different Classes of Ligands. ACS Chem. Biol., 12:2132-2138, 2017 Cited by PubMed: 28686408 DOI: 10.1021/acschembio.7b00004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation