2CN3
| Crystal Structures of Clostridium thermocellum Xyloglucanase | Descriptor: | BETA-1,4-XYLOGLUCAN HYDROLASE, CALCIUM ION, alpha-D-xylopyranose-(1-6)-beta-D-glucopyranose-(1-4)-[alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-[beta-D-galactopyranose-(1-2)-alpha-D-xylopyranose-(1-6)]beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Martinez-Fleites, C, Taylor, E.J, Guerreiro, C.I.P.D, Prates, J.A.M, Ferreira, L.M.A, Fontes, C.M.G.A, Baumann, M.J, Brumer, H, Davies, G.J. | Deposit date: | 2006-05-17 | Release date: | 2006-05-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structures of Clostridium Thermocellum Xyloglucanase, Xgh74A, Reveal the Structural Basis for Xyloglucan Recognition and Degradation J.Biol.Chem., 281, 2006
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1P26
| Crystal structure of zinc(II)-d(GGCGCC)2 | Descriptor: | 5'-D(*GP*GP*CP*GP*CP*C)-3', ZINC ION | Authors: | Labiuk, S.L, Delbaere, L.T, Lee, J.S. | Deposit date: | 2003-04-14 | Release date: | 2003-12-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Cobalt(II), nickel(II) and zinc(II) do not bind to intra-helical N(7)
guanine positions in the B-form crystal structure of d(GGCGCC) J.Biol.Inorg.Chem., 8, 2003
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441D
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1M6B
| Structure of the HER3 (ERBB3) Extracellular Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor protein-tyrosine kinase erbB-3, ... | Authors: | Leahy, D.J, Cho, H.-S. | Deposit date: | 2002-07-15 | Release date: | 2002-08-02 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the extracellular region of HER3 reveals an interdomain tether. Science, 297, 2002
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3G7V
| Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein | Descriptor: | GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ... | Authors: | Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. | Deposit date: | 2009-02-10 | Release date: | 2009-06-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009
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3S26
| Crystal Structure of Murine Siderocalin (Lipocalin 2, 24p3) | Descriptor: | Neutrophil gelatinase-associated lipocalin, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Correnti, C, Bandaranayake, A.D, Strong, R.K. | Deposit date: | 2011-05-16 | Release date: | 2011-09-28 | Last modified: | 2021-03-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors. Nucleic Acids Res., 39, 2011
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1OS3
| Dehydrated T6 human insulin at 100 K | Descriptor: | CHLORIDE ION, Insulin, ZINC ION | Authors: | Smith, G.D, Blessing, R.H. | Deposit date: | 2003-03-18 | Release date: | 2003-07-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Lessons from an aged, dried crystal of T(6) human insulin. Acta Crystallogr.,Sect.D, 59, 2003
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1HX6
| P3, THE MAJOR COAT PROTEIN OF THE LIPID-CONTAINING BACTERIOPHAGE PRD1. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, MAJOR CAPSID PROTEIN, ... | Authors: | Benson, S.D, Bamford, J.K.H, Bamford, D.H, Burnett, R.M. | Deposit date: | 2001-01-11 | Release date: | 2001-01-24 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The X-ray crystal structure of P3, the major coat protein of the lipid-containing bacteriophage PRD1, at 1.65 A resolution. Acta Crystallogr.,Sect.D, 58, 2002
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2X81
| STRUCTURE OF AURORA A IN COMPLEX WITH MLN8054 | Descriptor: | 4-{[9-CHLORO-7-(2,6-DIFLUOROPHENYL)-5H-PYRIMIDO[5,4-D][2]BENZAZEPIN-2-YL]AMINO}BENZOIC ACID, SERINE/THREONINE-PROTEIN KINASE 6 | Authors: | Savory, W, Mueller, I, Mason, C.S, Lamers, M, Williams, D.H, Eyers, P.A. | Deposit date: | 2010-03-05 | Release date: | 2010-05-05 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Drug-Resistant Aurora a Mutants for Cellular Target Validation of the Small Molecule Kinase Inhibitors Mln8054 and Mln8237. Acs Chem.Biol., 5, 2010
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1H5R
| Thymidylyltransferase complexed with Thimidine and Glucose-1-phospate | Descriptor: | 1-O-phosphono-alpha-D-glucopyranose, GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, SULFATE ION, ... | Authors: | Rosano, C, Zuccotti, S, Bolognesi, M. | Deposit date: | 2001-05-25 | Release date: | 2001-11-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic and Crystallographic Analyses Support a Sequential-Ordered Bi Bi Catalytic Mechanism for Escherichia Coli Glucose-1-Phosphate Thymidylyltransferase J.Mol.Biol., 313, 2001
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3G3E
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1QL1
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6TFY
| Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18c | Descriptor: | Epidermal growth factor receptor, SULFATE ION, ~{N}-[5-[4-[[3-chloranyl-4-(pyridin-2-ylmethoxy)phenyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(3-oxidanylpropoxy)phenyl]propanamide | Authors: | Niggenaber, J, Mueller, M.P, Rauh, D. | Deposit date: | 2019-11-14 | Release date: | 2020-09-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach. J.Med.Chem., 63, 2020
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4JPV
| Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | Authors: | Zhou, T, Moquin, S, Kwong, P.D. | Deposit date: | 2013-03-19 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.827 Å) | Cite: | Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization. Cell(Cambridge,Mass.), 153, 2013
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4NRS
| Crystal Structure of Glycoside Hydrolase Family 5 Mannosidase (E202A mutant) from Rhizomucor miehei in complex with mannobiose | Descriptor: | Exo-beta-1,4-mannosidase, beta-D-mannopyranose-(1-4)-alpha-D-mannopyranose | Authors: | Jiang, Z.Q, Zhou, P, Yang, S.Q, Liu, Y, Yan, Q.J. | Deposit date: | 2013-11-27 | Release date: | 2014-11-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase. Acta Crystallogr.,Sect.D, 70, 2014
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4AB1
| Recombinant Human Carboxylesterase 1 from whole Cabbage Loopers | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LIVER CARBOXYLESTERASE 1, THIOCYANATE ION | Authors: | Greenblatt, H.M, Otto, T.C, Cerasoli, D.M, Sussman, J.L. | Deposit date: | 2011-12-06 | Release date: | 2012-03-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of Recombinant Human Carboxylesterase 1 Isolated from Whole Cabbage Looper Larvae. Acta Crystallogr.,Sect.F, 68, 2012
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5UUC
| Tetragonal thermolysin cryocooled to 100 K with 50% mpd as cryoprotectant | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, ... | Authors: | Juers, D.H. | Deposit date: | 2017-02-16 | Release date: | 2017-03-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.60000932 Å) | Cite: | The impact of cryosolution thermal contraction on proteins and protein crystals: volumes, conformation and order. Acta Crystallogr D Struct Biol, 74, 2018
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3U69
| Unliganded wild-type human thrombin | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Figueiredo, A.C, Clement, C.C, Philipp, M, Barbosa Pereira, P.J. | Deposit date: | 2011-10-12 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Rational design and characterization of d-phe-pro-d-arg-derived direct thrombin inhibitors. Plos One, 7, 2012
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1R1L
| Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin P14-P9 peptide, Antithrombin-III, ... | Authors: | Zhou, A, Huntington, J.A, Lomas, D.A, Stein, P.E, Carrell, R.W. | Deposit date: | 2003-09-24 | Release date: | 2004-10-05 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Serpins and the design of peptides to block intermolecular beta-linkages To be Published
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3B75
| Crystal Structure of Glycated Human Haemoglobin | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, OXYGEN MOLECULE, ... | Authors: | Saraswathi, N.T, Syakhovich, V.E, Bokut, S.B, Moras, D, Ruff, M. | Deposit date: | 2007-10-30 | Release date: | 2008-10-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The effect of hemoglobin glycosylation on diabete linked oxidative stress To be Published
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1LL4
| STRUCTURE OF C. IMMITIS CHITINASE 1 COMPLEXED WITH ALLOSAMIDIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-allopyranose, ALLOSAMIZOLINE, CHITINASE 1 | Authors: | Bortone, K, Monzingo, A.F, Ernst, S, Robertus, J.D. | Deposit date: | 2002-04-26 | Release date: | 2002-09-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | THE STRUCTURE OF AN ALLOSAMIDIN COMPLEX WITH THE Coccidioides IMMITIS CHITINASE DEFINES A ROLE FOR A SECOND ACID RESIDUE IN SUBSTRATE-ASSISTED MECHANISM J.Mol.Biol., 320, 2002
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3U8J
| Crystal structure of the acetylcholine binding protein (AChBP) from Lymnaea stagnalis in complex with NS3531 (1-(pyridin-3-yl)-1,4-diazepane) | Descriptor: | 1-(pyridin-3-yl)-1,4-diazepane, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholine-binding protein, ... | Authors: | Rohde, L.A.H, Ahring, P.K, Jensen, M.L, Nielsen, E.O, Peters, D, Helgstrand, C, Krintel, C, Harpsoe, K, Gajhede, M, Kastrup, J.S, Balle, T. | Deposit date: | 2011-10-17 | Release date: | 2011-12-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Intersubunit bridge formation governs agonist efficacy at nicotinic acetylcholine alpha 4 beta 2 receptors: unique role of halogen bonding revealed. J.Biol.Chem., 287, 2012
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5V3F
| Co-crystal structure of the fluorogenic RNA Mango | Descriptor: | 4-{[(2S)-3-{2,16-dioxo-20-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-6,9,12-trioxa-3,15-diazaicosan-1-yl}-2,3-dihydro-1,3-benzothiazol-2-yl]methyl}-1-methylquinolin-1-ium, PHOSPHATE ION, POTASSIUM ION, ... | Authors: | Trachman, R.J, Ferre-D'Amare, A.R. | Deposit date: | 2017-03-07 | Release date: | 2017-05-24 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for high-affinity fluorophore binding and activation by RNA Mango. Nat. Chem. Biol., 13, 2017
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4AC1
| The structure of a fungal endo-beta-N-acetylglucosaminidase from glycosyl hydrolase family 18, at 1.3A resolution | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ENDO-N-ACETYL-BETA-D-GLUCOSAMINIDASE, ... | Authors: | Stals, I, Karkehabadi, S, Devreese, B, Kim, S, Ward, M, Sandgren, M. | Deposit date: | 2011-12-12 | Release date: | 2012-08-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | High Resolution Crystal Structure of the Endo-N-Acetyl-Beta- D-Glucosaminidase Responsible for the Deglycosylation of Hypocrea Jecorina Cellulases. Plos One, 7, 2012
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4NML
| 2.60 Angstrom resolution crystal structure of putative ribose 5-phosphate isomerase from Toxoplasma gondii ME49 in complex with DL-Malic acid | Descriptor: | CHLORIDE ION, D-MALATE, Ribulose 5-phosphate isomerase | Authors: | Halavaty, A.S, Dubrovska, I, Flores, K, Shanmugam, D, Shuvalova, L, Roos, D, Ruan, J, Ngo, H, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-11-15 | Release date: | 2013-12-04 | Last modified: | 2021-01-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii . Front Cell Infect Microbiol, 8, 2018
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