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7BY1
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BU of 7by1 by Molmil
Crystal structure of GCN5 PCAF N-terminal domain
Descriptor: Histone acetyltransferase KAT2A, ZINC ION
Authors:Hibi, R, Toma-Fukai, S, Shimizu, T.
Deposit date:2020-04-21
Release date:2020-08-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure.
J.Biol.Chem., 295, 2020
3WFB
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BU of 3wfb by Molmil
Reduced cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with antibody fragment
Descriptor: CALCIUM ION, CHLORIDE ION, FE (III) ION, ...
Authors:Sato, N, Ishii, S, Hino, T, Sugimoto, H, Fukumori, Y, Shiro, Y, Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes.
Proteins, 82, 2014
3SE4
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BU of 3se4 by Molmil
human IFNw-IFNAR ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interferon alpha/beta receptor 1, Interferon alpha/beta receptor 2, ...
Authors:Thomas, C, Garcia, K.C.
Deposit date:2011-06-10
Release date:2011-08-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5001 Å)
Cite:Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
3I7L
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BU of 3i7l by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of DDB2
Descriptor: DNA damage-binding protein 1, DNA damage-binding protein 2
Authors:Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
5FUI
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BU of 5fui by Molmil
Crystal structure of the C-terminal CBM6 of LamC a marine laminarianse from Zobellia galactanivorans
Descriptor: 2-AMINOMETHYL-PYRIDINE, ENDO-1,3-BETA-GLUCANASE, FAMILY GH16, ...
Authors:Labourel, A, Jam, M, Legentil, L, Sylla, B, Hehemann, J.H, Ficko-Blean, E, Ferrieres, V, Czjzek, M, Michel, G.
Deposit date:2016-01-27
Release date:2016-03-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Unraveling the Multivalent Binding of a Marine Family 6 Carbohydrate-Binding Module with its Native Laminarin Ligand.
FEBS J., 283, 2016
2JGS
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BU of 2jgs by Molmil
Circular permutant of avidin
Descriptor: BIOTIN, CIRCULAR PERMUTANT OF AVIDIN
Authors:Maatta, J.A.E, Hytonen, V.P, Airenne, T.T, Niskanen, E, Johnson, M.S, Kulomaa, M.S, Nordlund, H.R.
Deposit date:2007-02-14
Release date:2008-03-04
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational Modification of Ligand-Binding Preference of Avidin by Circular Permutation and Mutagenesis.
Chembiochem, 9, 2008
3I7K
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BU of 3i7k by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WHX
Descriptor: DNA damage-binding protein 1, X protein
Authors:Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
4PFU
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BU of 4pfu by Molmil
Crystal structure of mannobiose bound oligopeptide ABC transporter, periplasmic oligopeptide-binding protein (TM1226) from THERMOTOGA MARITIMA at 2.05 A resolution
Descriptor: ABC transporter substrate-binding protein, MAGNESIUM ION, SULFATE ION, ...
Authors:Lu, X, Ghimire-Rijal, S, Cuneo, M.J.
Deposit date:2014-04-30
Release date:2014-09-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:Duplication of Genes in an ATP-binding Cassette Transport System Increases Dynamic Range While Maintaining Ligand Specificity.
J.Biol.Chem., 289, 2014
3WFC
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BU of 3wfc by Molmil
Reduced and carbonmonoxide-bound cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with antibody fragment
Descriptor: CALCIUM ION, CARBON MONOXIDE, FE (III) ION, ...
Authors:Sato, N, Ishii, S, Hino, T, Sugimoto, H, Fukumori, Y, Shiro, Y, Tosha, T.
Deposit date:2013-07-18
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of reduced and ligand-bound nitric oxide reductase provide insights into functional differences in respiratory enzymes.
Proteins, 82, 2014
3I8E
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BU of 3i8e by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR42A
Descriptor: DNA damage-binding protein 1, WD repeat-containing protein 42A
Authors:Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3M63
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BU of 3m63 by Molmil
Crystal structure of Ufd2 in complex with the ubiquitin-like (UBL) domain of Dsk2
Descriptor: PENTAETHYLENE GLYCOL, POTASSIUM ION, Ubiquitin conjugation factor E4, ...
Authors:Haenzelmann, P, Schindelin, H.
Deposit date:2010-03-15
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain.
J.Biol.Chem., 285, 2010
2WEW
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BU of 2wew by Molmil
Crystal structure of human apoM in complex with myristic acid
Descriptor: 1,2-ETHANEDIOL, APOLIPOPROTEIN M, MYRISTIC ACID
Authors:Sevvana, M, Ahnstrom, J, Egerer-Sieber, C, Dahlback, B, Muller, Y.A.
Deposit date:2009-04-02
Release date:2009-09-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M.
J.Mol.Biol., 393, 2009
3I89
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BU of 3i89 by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR22
Descriptor: DNA damage-binding protein 1, WD repeat-containing protein 22
Authors:Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
4FIL
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BU of 4fil by Molmil
Structure of FhuD2 from Staphylococcus Aureus with Bound Ferrioxamine B
Descriptor: 1,2-ETHANEDIOL, Ferric hydroxamate receptor 2, Ferrioxamine B, ...
Authors:Briere, L.K, Heinrichs, D.E, Shilton, B.H.
Deposit date:2012-06-08
Release date:2013-06-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal and solution structure analysis of FhuD2 from Staphylococcus aureus in multiple unliganded conformations and bound to ferrioxamine-B.
Biochemistry, 53, 2014
3M62
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BU of 3m62 by Molmil
Crystal structure of Ufd2 in complex with the ubiquitin-like (UBL) domain of Rad23
Descriptor: PENTAETHYLENE GLYCOL, POTASSIUM ION, UV excision repair protein RAD23, ...
Authors:Haenzelmann, P, Schindelin, H.
Deposit date:2010-03-15
Release date:2010-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The yeast E4 ubiquitin ligase Ufd2 interacts with the ubiquitin-like domains of Rad23 and Dsk2 via a novel and distinct ubiquitin-like binding domain.
J.Biol.Chem., 285, 2010
3S8W
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BU of 3s8w by Molmil
D2 domain of human IFNAR2
Descriptor: CHLORIDE ION, Interferon alpha/beta receptor 2
Authors:Thomas, C, Garcia, K.C.
Deposit date:2011-05-31
Release date:2011-08-31
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural linkage between ligand discrimination and receptor activation by type I interferons.
Cell(Cambridge,Mass.), 146, 2011
5UM3
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BU of 5um3 by Molmil
Crystal structure of the V122L mutant of human UBR-box domain from UBR2
Descriptor: E3 ubiquitin-protein ligase UBR2, ZINC ION
Authors:Munoz Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2017-01-26
Release date:2017-03-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.198 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
2UUO
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BU of 2uuo by Molmil
Crystal structure of MurD ligase in complex with D-Glu containing sulfonamide inhibitor
Descriptor: N-{[6-(PENTYLOXY)NAPHTHALEN-2-YL]SULFONYL}-D-GLUTAMIC ACID, SULFATE ION, UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE
Authors:Humljan, J, Kotnik, M, Contreras-Martel, C, Blanot, D, Urleb, U, Dessen, A, Solmajer, T, Gobec, S.
Deposit date:2007-03-06
Release date:2008-03-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.
J. Med. Chem., 51, 2008
3I8C
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BU of 3i8c by Molmil
Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A
Descriptor: DNA damage-binding protein 1, WD repeat-containing protein 21A
Authors:Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
5TDB
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BU of 5tdb by Molmil
Crystal structure of the human UBR-box domain from UBR2 in complex with asymmetrically double methylated arginine peptide
Descriptor: 1,2-ETHANEDIOL, DA2-ILE-PHE-SER peptide, E3 ubiquitin-protein ligase UBR2, ...
Authors:Munoz-Escobar, J, Kozlov, G, Gehring, K.
Deposit date:2016-09-19
Release date:2017-03-22
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:Bound Waters Mediate Binding of Diverse Substrates to a Ubiquitin Ligase.
Structure, 25, 2017
4R9D
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BU of 4r9d by Molmil
Crystal structure of Human galectin-3 CRD in complex with lactose (pH 7.9, PEG6000)
Descriptor: Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Su, J.Y.
Deposit date:2014-09-04
Release date:2015-03-11
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.239 Å)
Cite:The water network in galectin-3 ligand binding site guides inhibitor design.
Acta Biochim.Biophys.Sin., 47, 2015
1KKQ
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BU of 1kkq by Molmil
Crystal structure of the human PPAR-alpha ligand-binding domain in complex with an antagonist GW6471 and a SMRT corepressor motif
Descriptor: N-((2S)-2-({(1Z)-1-METHYL-3-OXO-3-[4-(TRIFLUOROMETHYL) PHENYL]PROP-1-ENYL}AMINO)-3-{4-[2-(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)ETHOXY]PHENYL}PROPYL)PROPANAMIDE, NUCLEAR RECEPTOR CO-REPRESSOR 2, PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR
Authors:Xu, H.E, Stanley, T.B, Montana, V.G, Lambert, M.H, Shearer, B.G, Cobb, J.E, McKee, D.D, Galardi, C.M, Nolte, R.T, Parks, D.J.
Deposit date:2001-12-10
Release date:2002-02-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha.
Nature, 415, 2002
3ZM5
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BU of 3zm5 by Molmil
CRYSTAL STRUCTURE OF MURF LIGASE IN COMPLEX WITH CYANOTHIOPHENE INHIBITOR
Descriptor: 2,4-bis(chloranyl)-N-[3-cyano-6-[(4-hydroxyphenyl)methyl]-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl]-5-morpholin-4-ylsulfonyl-benzamide, UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE
Authors:Hrast, M, Turk, S, Sosic, I, Knez, D, Randall, C.P, Barreteau, H, Contreras-Martel, C, Dessen, A, ONeill, A.J, Mengin-Lecreulx, D, Blanot, D, Gobec, S.
Deposit date:2013-02-05
Release date:2013-07-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Structure-Activity Relationships of New Cyanothiophene Inhibitors of the Essential Peptidoglycan Biosynthesis Enzyme Murf.
Eur.J.Med.Chem., 66C, 2013
4R9B
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BU of 4r9b by Molmil
Crystal structure of Human galectin-3 CRD in complex with lactose (pH 7.0, PEG 6000)
Descriptor: Galectin-3, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Su, J.Y.
Deposit date:2014-09-04
Release date:2015-03-11
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The water network in galectin-3 ligand binding site guides inhibitor design.
Acta Biochim.Biophys.Sin., 47, 2015
2WEX
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BU of 2wex by Molmil
Crystal structure of human apoM in complex with glycerol 1- myristic acid
Descriptor: (2R)-2,3-dihydroxypropyl tetradecanoate, 1,2-ETHANEDIOL, APOLIPOPROTEIN M
Authors:Sevvana, M, Ahnstrom, J, Egerer-Sieber, C, Dahlback, B, Muller, Y.A.
Deposit date:2009-04-02
Release date:2009-09-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M.
J.Mol.Biol., 393, 2009

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