4KH6
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![BU of 4kh6 by Molmil](/molmil-images/mine/4kh6) | |
2A5F
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![BU of 2a5f by Molmil](/molmil-images/mine/2a5f) | Cholera toxin A1 subunit bound to its substrate, NAD+, and its human protein activator, ARF6 | Descriptor: | ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ... | Authors: | O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J. | Deposit date: | 2005-06-30 | Release date: | 2005-08-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Structural basis for the activation of cholera toxin by human ARF6-GTP. Science, 309, 2005
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1KDN
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![BU of 1kdn by Molmil](/molmil-images/mine/1kdn) | STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Cherfils, J, Xu, Y.W, Morera, S, Janin, J. | Deposit date: | 1996-09-10 | Release date: | 1997-04-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP. Proc.Natl.Acad.Sci.USA, 94, 1997
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2BWK
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![BU of 2bwk by Molmil](/molmil-images/mine/2bwk) | Murine angiogenin, sulphate complex | Descriptor: | ANGIOGENIN, SULFATE ION | Authors: | Holloway, D.E, Chavali, G.B, Hares, M.C, Subramanian, V, Acharya, K.R. | Deposit date: | 2005-07-15 | Release date: | 2005-11-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of Murine Angiogenin: Features of the Substrate- and Cell-Binding Regions and Prospects for Inhibitor-Binding Studies. Acta Crystallogr.,Sect.D, 61, 2005
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1MN7
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![BU of 1mn7 by Molmil](/molmil-images/mine/1mn7) | NDP kinase mutant (H122G;N119S;F64W) in complex with aBAZTTP | Descriptor: | 3'-AZIDO-3'-DEOXY-THYMIDINE-5'-ALPHA BORANO TRIPHOSPHATE, MAGNESIUM ION, NDP kinase | Authors: | gallois-montbrun, s, schneider, b, chen, y, giacomoni-fernandes, v, mulard, l, morera, s, janin, j, deville-bonne, d, veron, m. | Deposit date: | 2002-09-05 | Release date: | 2002-10-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Improving nucleoside diphosphate kinase for antiviral nucleotide analogs activation J.BIOL.CHEM., 277, 2002
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2BEF
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![BU of 2bef by Molmil](/molmil-images/mine/2bef) | CRYSTAL STRUCTURE OF NDP KINASE COMPLEXED WITH MG, ADP, AND BEF3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... | Authors: | Xu, Y.W, Cherfils, J. | Deposit date: | 1998-05-26 | Release date: | 1998-08-12 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP. Proc.Natl.Acad.Sci.USA, 94, 1997
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4KH5
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![BU of 4kh5 by Molmil](/molmil-images/mine/4kh5) | Toxoplasma gondii NTPDase1 C258S/C268S in complex with Mg and AMPNP | Descriptor: | 5'-O-[(R)-hydroxy(phosphonoamino)phosphoryl]adenosine, MAGNESIUM ION, Nucleoside-triphosphatase 2 | Authors: | Krug, U, Totzauer, R, Strater, N. | Deposit date: | 2013-04-30 | Release date: | 2013-11-06 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate base. Chembiochem, 14, 2013
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4KH4
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![BU of 4kh4 by Molmil](/molmil-images/mine/4kh4) | Toxoplasma gondii NTPDase1 C258S/C268S in complex with Mg and AMPPNP | Descriptor: | MAGNESIUM ION, Nucleoside-triphosphatase 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Krug, U, Totzauer, R, Strater, N. | Deposit date: | 2013-04-30 | Release date: | 2013-11-06 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate base. Chembiochem, 14, 2013
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1NPK
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![BU of 1npk by Molmil](/molmil-images/mine/1npk) | REFINED X-RAY STRUCTURE OF DICTYOSTELIUM NUCLEOSIDE DIPHOSPHATE KINASE AT 1,8 ANGSTROMS RESOLUTION | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE | Authors: | Janin, J, Morera, S, Lebras, G, Lascu, I, Veron, M. | Deposit date: | 1994-07-27 | Release date: | 1994-11-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Refined X-ray structure of Dictyostelium discoideum nucleoside diphosphate kinase at 1.8 A resolution. J.Mol.Biol., 243, 1994
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1NSP
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![BU of 1nsp by Molmil](/molmil-images/mine/1nsp) | MECHANISM OF PHOSPHATE TRANSFER BY NUCLEOSIDE DIPHOSPHATE KINASE: X-RAY STRUCTURES OF A PHOSPHO-HISTIDINE INTERMEDIATE OF THE ENZYMES FROM DROSOPHILA AND DICTYOSTELIUM | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE | Authors: | Janin, J, Morera, S, Chiadmi, M, Lebras, G, Lascu, I. | Deposit date: | 1995-04-18 | Release date: | 1995-07-10 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanism of phosphate transfer by nucleoside diphosphate kinase: X-ray structures of the phosphohistidine intermediate of the enzymes from Drosophila and Dictyostelium. Biochemistry, 34, 1995
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1PAE
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![BU of 1pae by Molmil](/molmil-images/mine/1pae) | nucleoside diphosphate kinase | Descriptor: | Nucleoside diphosphate kinase, cytosolic, SELENIUM ATOM | Authors: | Strub, M.-P, Hoh, F, Sanchez, J.-F, Strub, J.M, Bock, A, Aumelas, A, Dumas, C. | Deposit date: | 2003-05-14 | Release date: | 2003-11-11 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Selenomethionine and Selenocysteine Double Labeling Strategy for Crystallographic Phasing Structure, 11, 2003
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8XT0
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![BU of 8xt0 by Molmil](/molmil-images/mine/8xt0) | Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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8XT2
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![BU of 8xt2 by Molmil](/molmil-images/mine/8xt2) | Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline | Descriptor: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | Authors: | Li, X, Wang, M, Cheng, J. | Deposit date: | 2024-01-10 | Release date: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
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6A62
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![BU of 6a62 by Molmil](/molmil-images/mine/6a62) | Placental protein 13/galectin-13 variant R53HH57RD33G with Lactose | Descriptor: | Galactoside-binding soluble lectin 13, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Su, J. | Deposit date: | 2018-06-26 | Release date: | 2018-12-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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6A64
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![BU of 6a64 by Molmil](/molmil-images/mine/6a64) | Placental protein 13/galectin-13 variant R53HR55NH57RD33G with Lactose | Descriptor: | Galactoside-binding soluble lectin 13, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Su, J. | Deposit date: | 2018-06-26 | Release date: | 2018-12-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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6A9X
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![BU of 6a9x by Molmil](/molmil-images/mine/6a9x) | Crystal Structure of AnkG/GABARAP Complex | Descriptor: | Ankyrin-3, Gamma-aminobutyric acid receptor-associated protein | Authors: | Wang, C, Li, J, Chen, K, Zhang, M. | Deposit date: | 2018-07-16 | Release date: | 2018-12-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Ankyrin-G regulates forebrain connectivity and network synchronization via interaction with GABARAP. Mol. Psychiatry, 2018
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6A65
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![BU of 6a65 by Molmil](/molmil-images/mine/6a65) | Placental protein 13/galectin-13 variant R53HR55N with Tris | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Galactoside-binding soluble lectin 13 | Authors: | Su, J. | Deposit date: | 2018-06-26 | Release date: | 2018-12-26 | Method: | X-RAY DIFFRACTION (1.771 Å) | Cite: | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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6AH6
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![BU of 6ah6 by Molmil](/molmil-images/mine/6ah6) | M500V mutant of Coronin coiled coil domain | Descriptor: | Coronin-like protein | Authors: | Ansari, A, Karade, S.S, Pratap, J.V. | Deposit date: | 2018-08-16 | Release date: | 2019-08-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular and structural analysis of a mechanical transition of helices in the L. donovani coronin coiled-coil domain. Int.J.Biol.Macromol., 143, 2020
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6A63
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![BU of 6a63 by Molmil](/molmil-images/mine/6a63) | Placental protein 13/galectin-13 variant R53HH57R with Lactose | Descriptor: | Galactoside-binding soluble lectin 13, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Su, J. | Deposit date: | 2018-06-26 | Release date: | 2018-12-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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6A66
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![BU of 6a66 by Molmil](/molmil-images/mine/6a66) | Placental protein 13/galectin-13 variant R53H with Tris | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Galactoside-binding soluble lectin 13 | Authors: | Su, J.Y. | Deposit date: | 2018-06-26 | Release date: | 2018-12-26 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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5X6U
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![BU of 5x6u by Molmil](/molmil-images/mine/5x6u) | Crystal structure of human heteropentameric complex | Descriptor: | Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... | Authors: | Yonehara, R, Nada, S, Nakai, T, Nakai, M, Kitamura, A, Ogawa, A, Nakatsumi, H, Nakayama, K.I, Li, S, Standley, D.M, Yamashita, E, Nakagawa, A, Okada, M. | Deposit date: | 2017-02-23 | Release date: | 2017-12-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the assembly of the Ragulator-Rag GTPase complex. Nat Commun, 8, 2017
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5Y39
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![BU of 5y39 by Molmil](/molmil-images/mine/5y39) | Crystal structure of Ragulator complex (p18 76-145) | Descriptor: | Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... | Authors: | Zhang, T, Ding, J. | Deposit date: | 2017-07-28 | Release date: | 2017-12-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1 Nat Commun, 8, 2017
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5YK3
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![BU of 5yk3 by Molmil](/molmil-images/mine/5yk3) | human Ragulator complex | Descriptor: | Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... | Authors: | Wu, G, Mu, Z. | Deposit date: | 2017-10-12 | Release date: | 2019-01-23 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Structural insight into the Ragulator complex which anchors mTORC1 to the lysosomal membrane Cell Discov, 3, 2017
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5Y3A
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![BU of 5y3a by Molmil](/molmil-images/mine/5y3a) | Crystal structure of Ragulator complex (p18 49-161) | Descriptor: | Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, Ragulator complex protein LAMTOR3, ... | Authors: | Zhang, T, Ding, J. | Deposit date: | 2017-07-28 | Release date: | 2017-12-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1. Nat Commun, 8, 2017
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5DKD
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![BU of 5dkd by Molmil](/molmil-images/mine/5dkd) | Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe | Descriptor: | (2E)-1-(2-hydroxyphenyl)-3-[(1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]hept-2-yl]prop-2-en-1-one, 1,2-ETHANEDIOL, Transcription activator BRG1, ... | Authors: | Tallant, C, Owen, D.R, Gerstenberger, B.S, Fedorov, O, Savitsky, P, Nunez-Alonso, G, Newman, J.A, Filippakopoulos, P, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Muller, S, Knapp, S. | Deposit date: | 2015-09-03 | Release date: | 2015-10-14 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe To Be Published
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