2A5F

Cholera toxin A1 subunit bound to its substrate, NAD+, and its human protein activator, ARF6

Summary for 2A5F

• Entry DOI: 10.2210/pdb2a5f/pdb
• Descriptor: ADP-ribosylation factor 6, Cholera enterotoxin, A chain, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: protein transport/transferase, protein transport-transferase complex
• Biological source: Homo sapiens (human); More
• Cellular location: Golgi apparatus: P62330
• Total number of polymer chains: 2
• Total formula weight: 43146.94

Authors

O'Neal, C.J.,Jobling, M.G.,Holmes, R.K.,Hol, W.G.J. (deposition date: 2005-06-30, release date: 2005-08-16, Last modification date: 2024-04-03)

• Primary citation: O'Neal, C.J.,Jobling, M.G.,Holmes, R.K.,Hol, W.G.; Structural basis for the activation of cholera toxin by human ARF6-GTP.; Science, 309:1093-1096, 2005; PubMed: 16099990; DOI: 10.1126/science.1113398

Experimental method

X-RAY DIFFRACTION (2.02 Å)