5DKD

Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe

Summary for 5DKD

• Entry DOI: 10.2210/pdb5dkd/pdb
• Descriptor: Transcription activator BRG1, ZINC ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: swi-snf complex, chromatin remodeling, brg associated factors (baf), transcription, hydrolase
• Biological source: Homo sapiens (Human)
• Cellular location: Nucleus : P51532
• Total number of polymer chains: 2
• Total formula weight: 29606.87

Authors

Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Fedorov, O.,Savitsky, P.,Nunez-Alonso, G.,Newman, J.A.,Filippakopoulos, P.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S. (deposition date: 2015-09-03, release date: 2015-10-14, Last modification date: 2024-01-10)

• Primary citation: Tallant, C.,Owen, D.R.,Gerstenberger, B.S.,Fedorov, O.,Savitsky, P.,Nunez-Alonso, G.,Newman, J.A.,Filippakopoulos, P.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Muller, S.,Knapp, S.; Crystal structure of the bromodomain of human BRG1 (SMARCA4) in complex with PFI-3 chemical probe; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)