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4GK6
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BU of 4gk6 by Molmil
X-ray crystal structure of a hypothetical deoxyuridine 5-triphosphate nucleotidohydrolase from Mycobacterium abscessus
Descriptor: CHLORIDE ION, Deoxyuridine 5'-triphosphate nucleotidohydrolase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2012-08-10
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3EO0
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BU of 3eo0 by Molmil
Structure of the Transforming Growth Factor-Beta Neutralizing Antibody GC-1008
Descriptor: GC-1008 Fab Heavy Chain, GC-1008 Fab Light Chain, GLYCEROL
Authors:Gruetter, C, Gruetter, M.G.
Deposit date:2008-09-26
Release date:2008-12-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A cytokine-neutralizing antibody as a structural mimetic of 2 receptor interactions
Proc.Natl.Acad.Sci.Usa, 105, 2008
3E3Q
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BU of 3e3q by Molmil
Structure of the 3alpham13 high-affinity mutant of the 2C TCR in complex with Ld/QL9
Descriptor: H-2 class I histocompatibility antigen, L-D alpha chain, QL9 peptide, ...
Authors:Colf, L.A, Garcia, K.C.
Deposit date:2008-08-07
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation.
J.Immunol., 181, 2008
3EOM
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BU of 3eom by Molmil
2.4 A crystal structure of native glutaryl-coa dehydrogenase from Burkholderia pseudomallei
Descriptor: Glutaryl-CoA dehydrogenase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-28
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.398 Å)
Cite:Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening.
Acta Crystallogr.,Sect.F, 67, 2011
4GKN
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BU of 4gkn by Molmil
A2-MHC Complex carrying FATGIGIITV
Descriptor: Beta-2-microglobulin, FAT Cognate peptide, MHC class I antigen, ...
Authors:Sewell, A.K, Rizkallah, P.J, Cole, D.K, Wooldridge, L, Price, D.A.
Deposit date:2012-08-13
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.753 Å)
Cite:T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting.
J.Biol.Chem., 287, 2012
3E2C
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BU of 3e2c by Molmil
Escherichia coli Bacterioferritin Mutant E128R/E135R
Descriptor: 1,2-ETHANEDIOL, Bacterioferritin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Wong, S.G, Tom-Yew, S.A.L, Lewin, A, Le Brun, N.E, Moore, G.R, Murphy, M.E.P, Mauk, A.G.
Deposit date:2008-08-05
Release date:2009-05-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Mechanistic Studies of a Stabilized Subunit Dimer Variant of Escherichia coli Bacterioferritin Identify Residues Required for Core Formation.
J.Biol.Chem., 284, 2009
3E2K
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BU of 3e2k by Molmil
Crystal Structure of the KPC-2 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP)
Descriptor: Beta-lactamase inhibitory protein, Carbapenemase
Authors:Hanes, M.S, Jude, K.M, Berger, J.M, Bonomo, R.A, Handel, T.M.
Deposit date:2008-08-05
Release date:2009-08-04
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein
Biochemistry, 48, 2009
3PKX
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BU of 3pkx by Molmil
Crystal Structure of Toxoflavin Lyase (TflA) bound to Mn(II) and Toxoflavin
Descriptor: 1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione, MANGANESE (II) ION, Toxoflavin lyase (TflA)
Authors:Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E.
Deposit date:2010-11-12
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Toxoflavin lyase requires a novel 1-his-2-carboxylate facial triad .
Biochemistry, 50, 2011
3E7D
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BU of 3e7d by Molmil
Crystal Structure of Precorrin-8X Methyl Mutase CbiC/CobH from Brucella melitensis
Descriptor: CobH, precorrin-8X methylmutase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-08-18
Release date:2008-08-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Precorrin-8X Methyl Mutase CbiC/CobH from Brucella melitensis
To be Published
3PP2
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BU of 3pp2 by Molmil
Crystal structure of the pleckstrin homology domain of ArhGAP27
Descriptor: CITRIC ACID, GLYCEROL, Rho GTPase-activating protein 27, ...
Authors:Shen, L, Tempel, W, Tong, Y, Nedyalkova, L, Li, Y, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-11-23
Release date:2010-12-08
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.421 Å)
Cite:Crystal structure of the pleckstrin homology domain of ArhGAP27
to be published
3E89
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BU of 3e89 by Molmil
Crystal Structure of the the open NaK channel-low Na+ complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, Potassium channel protein, ...
Authors:Jiang, Y, Alam, A.
Deposit date:2008-08-19
Release date:2008-12-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of ion selectivity in the NaK channel
Nat.Struct.Mol.Biol., 16, 2009
3E8G
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Crystal Structure of the the open NaK channel-Na+/Ca2+ complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CESIUM ION, ...
Authors:Jiang, Y, Alam, A.
Deposit date:2008-08-19
Release date:2008-12-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of ion selectivity in the NaK channel
Nat.Struct.Mol.Biol., 16, 2009
3E94
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BU of 3e94 by Molmil
Crystal structure of RXRalpha ligand binding domain in complex with tributyltin and a coactivator fragment
Descriptor: ACETATE ION, Nuclear receptor coactivator 2 peptide, Retinoic acid receptor RXR-alpha, ...
Authors:Bourguet, W, Le Maire, A.
Deposit date:2008-08-21
Release date:2009-03-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Activation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors
Embo Rep., 10, 2009
3PQ5
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BU of 3pq5 by Molmil
Structure of I274C variant of E. coli KatE[] - Images 19-24
Descriptor: CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE 17R, 18S, ...
Authors:Loewen, P.C, Jha, V, Louis, S, Chelikani, P, Carpena, X, Fita, I.
Deposit date:2010-11-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Modulation of heme orientation and binding by a single residue in catalase HPII of Escherichia coli.
Biochemistry, 50, 2011
3E95
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BU of 3e95 by Molmil
Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a
Descriptor: UNKNOWN ATOM OR ION, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2
Authors:Wernimont, A.K, Lam, A, Ali, A, Brokx, S, Lin, Y.H, Zhao, Y, Lew, J, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Wilkstrom, M, BOuntra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Qiu, W, Brand, V.B, Structural Genomics Consortium (SGC)
Deposit date:2008-08-21
Release date:2008-09-30
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a
TO BE PUBLISHED
4GN2
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BU of 4gn2 by Molmil
Crystal Structure of OXA-45, a Class D beta-lactamase with extended spectrum activity
Descriptor: Oxacillinase
Authors:Martin, J.D, Xiong, X.L, Catto, L.E, Toleman, M.A, Walsh, T.R, Clarke, A.R, Spencer, J.
Deposit date:2012-08-16
Release date:2013-08-21
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural and Kinetic Characterization of OXA-45, a Class D beta-Lactamase with Extended Spectrum activity
To be Published
3EA9
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BU of 3ea9 by Molmil
Crystal structure of SARS-CoV main protease quadruple mutant STIF/A with one molecule in one asymmetric unit
Descriptor: 3C-like proteinase
Authors:Shi, J.H, Jayaraman, S, Song, J.X.
Deposit date:2008-08-25
Release date:2009-09-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:crystal structure of SARS-CoV Mpro quadruple mutant
To be Published
3EAP
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BU of 3eap by Molmil
Crystal structure of the RhoGAP domain of ARHGAP11A
Descriptor: Rho GTPase-activating protein 11A, UNKNOWN ATOM OR ION
Authors:Shen, Y, Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium, Structural Genomics Consortium (SGC)
Deposit date:2008-08-26
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the RhoGAP domain of ARHGAP11A
To be Published
4GBW
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BU of 4gbw by Molmil
Crystal Structure of AMP complexes of Porcine Liver Fructose-1,6-bisphosphatase Mutant A54L with 1,2-propanediol as Cryo-protectant
Descriptor: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Honzatko, R.B, Gao, Y.
Deposit date:2012-07-28
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Water Structure of the Central Hydrophobic Cavity of Mammalian Fructose-1,6-bisphosphatase: a Potential Thermodynamic Determinant of Allowed Quaternary States
To be published
3EAY
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BU of 3eay by Molmil
Crystal structure of the human SENP7 catalytic domain
Descriptor: SULFATE ION, Sentrin-specific protease 7
Authors:Lima, C.D, Reverter, D.
Deposit date:2008-08-26
Release date:2008-09-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the Human SENP7 Catalytic Domain and Poly-SUMO Deconjugation Activities for SENP6 and SENP7.
J.Biol.Chem., 283, 2008
3PUN
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BU of 3pun by Molmil
Crystal structure of P domain dimer of Norovirus VA207 with Lewis y tetrasaccharide
Descriptor: Capsid, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Chen, Y, Tan, M, Xia, M, Hao, N, Zhang, X.C, Huang, P, Jiang, X, Li, X, Rao, Z.
Deposit date:2010-12-06
Release date:2011-08-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens
Plos Pathog., 7, 2011
3PVR
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BU of 3pvr by Molmil
The Phenylacetyl-CoA monooxygenase PaaAC subcomplex with benzoyl-CoA
Descriptor: GLYCEROL, Phenylacetic acid degradation protein paaA, Phenylacetic acid degradation protein paaC, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2010-12-07
Release date:2011-01-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Studies of the Escherichia coli Phenylacetyl-CoA Monooxygenase Complex.
J.Biol.Chem., 286, 2011
3EO3
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BU of 3eo3 by Molmil
Crystal structure of the N-acetylmannosamine kinase domain of human GNE protein
Descriptor: Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UNKNOWN ATOM OR ION, ZINC ION
Authors:Nedyalkova, L, Tong, Y, Rabeh, W.M, Hong, B, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-09-26
Release date:2008-10-07
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal structure of the N-acetylmannosamine kinase domain of GNE.
Plos One, 4, 2009
3EOL
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BU of 3eol by Molmil
2.0A crystal structure of isocitrate lyase from Brucella melitensis (P43212)
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, isocitrate lyase
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-28
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of isocitrate lyase from Brucella melitensis
To be Published
3PWP
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BU of 3pwp by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the bound HuD peptide
Descriptor: A6 TCR alpha chain, A6 TCR beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011

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