1A6Q
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![BU of 1a6q by Molmil](/molmil-images/mine/1a6q) | CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION | Descriptor: | MANGANESE (II) ION, PHOSPHATASE 2C, PHOSPHATE ION | Authors: | Das, A.K, Helps, N.R, Cohen, P.T.W, Barford, D. | Deposit date: | 1998-02-27 | Release date: | 1998-05-27 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution. EMBO J., 15, 1996
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1AHD
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![BU of 1ahd by Molmil](/molmil-images/mine/1ahd) | DETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX | Descriptor: | DNA (5'-D(*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), Homeotic protein antennapedia | Authors: | Billeter, M, Qian, Y.Q, Otting, G, Muller, M, Gehring, W.J, Wuthrich, K. | Deposit date: | 1993-04-02 | Release date: | 1993-10-31 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex. J.Mol.Biol., 234, 1993
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1AD6
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![BU of 1ad6 by Molmil](/molmil-images/mine/1ad6) | DOMAIN A OF HUMAN RETINOBLASTOMA TUMOR SUPPRESSOR | Descriptor: | RETINOBLASTOMA TUMOR SUPPRESSOR | Authors: | Kim, H.Y, Cho, Y. | Deposit date: | 1997-02-21 | Release date: | 1998-08-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural similarity between the pocket region of retinoblastoma tumour suppressor and the cyclin-box. Nat.Struct.Biol., 4, 1997
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1B39
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![BU of 1b39 by Molmil](/molmil-images/mine/1b39) | HUMAN CYCLIN-DEPENDENT KINASE 2 PHOSPHORYLATED ON THR 160 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (CELL DIVISION PROTEIN KINASE 2) | Authors: | Brown, N.R, Noble, M.E.M, Lawrie, A.M, Morris, M.C, Tunnah, P, Divita, G, Johnson, L.N, Endicott, J.A. | Deposit date: | 1998-12-17 | Release date: | 1998-12-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity. J.Biol.Chem., 274, 1999
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1B4T
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![BU of 1b4t by Molmil](/molmil-images/mine/1b4t) | H48C YEAST CU(II)/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE | Descriptor: | CHLORIDE ION, COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ... | Authors: | Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D. | Deposit date: | 1998-12-23 | Release date: | 1999-12-23 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A structure-based mechanism for copper-zinc superoxide dismutase. Biochemistry, 38, 1999
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1B4L
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![BU of 1b4l by Molmil](/molmil-images/mine/1b4l) | 15 ATMOSPHERE OXYGEN YEAST CU/ZN SUPEROXIDE DISMUTASE ROOM TEMPERATURE (298K) STRUCTURE | Descriptor: | COPPER (II) ION, PROTEIN (CU/ZN SUPEROXIDE DISMUTASE), ZINC ION | Authors: | Hart, P.J, Balbirnie, M.M, Ogihara, N.L, Nersissian, A.M, Weiss, M.S, Valentine, J.S, Eisenberg, D. | Deposit date: | 1998-12-22 | Release date: | 1999-12-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A structure-based mechanism for copper-zinc superoxide dismutase. Biochemistry, 38, 1999
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1B0F
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![BU of 1b0f by Molmil](/molmil-images/mine/1b0f) | CRYSTAL STRUCTURE OF HUMAN NEUTROPHIL ELASTASE WITH MDL 101, 146 | Descriptor: | 1-{3-METHYL-2-[4-(MORPHOLINE-4-CARBONYL)-BENZOYLAMINO]-BUTYRYL}-PYRROLIDINE-2-CARBOXYLIC ACID (3,3,4,4,4-PENTAFLUORO-1-ISOPROPYL-2-OXO-BUTYL)-AMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (ELASTASE) | Authors: | Schreuder, H.A, Metz, W.A, Peet, N.P, Pelton, J.T, Tardif, C. | Deposit date: | 1998-11-09 | Release date: | 1998-11-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Inhibition of human neutrophil elastase. 4. Design, synthesis, X-ray crystallographic analysis, and structure-activity relationships for a series of P2-modified, orally active peptidyl pentafluoroethyl ketones. J.Med.Chem., 41, 1998
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7X3X
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![BU of 7x3x by Molmil](/molmil-images/mine/7x3x) | Cryo-EM structure of N1 nucleosome-RA | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Lifei, L, Kangjing, C, Chen, Z. | Deposit date: | 2022-03-01 | Release date: | 2023-09-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of the ISW1a complex bound to the dinucleosome. Nat.Struct.Mol.Biol., 31, 2024
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7X3T
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![BU of 7x3t by Molmil](/molmil-images/mine/7x3t) | Cryo-EM structure of ISW1a-dinucleosome | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (343-MER), ... | Authors: | Lifei, L, Kangjing, C, Chen, Z. | Deposit date: | 2022-03-01 | Release date: | 2023-09-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Structure of the ISW1a complex bound to the dinucleosome. Nat.Struct.Mol.Biol., 31, 2024
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7X3W
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![BU of 7x3w by Molmil](/molmil-images/mine/7x3w) | Cryo-EM structure of ISW1-N1 nucleosome | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (146-MER), ... | Authors: | Lifei, L, Kangjing, C, Chen, Z. | Deposit date: | 2022-03-01 | Release date: | 2023-09-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the ISW1a complex bound to the dinucleosome. Nat.Struct.Mol.Biol., 31, 2024
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7AO9
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![BU of 7ao9 by Molmil](/molmil-images/mine/7ao9) | Structure of the core MTA1/HDAC1/MBD2 NURD deacetylase complex | Descriptor: | Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ... | Authors: | Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. | Deposit date: | 2020-10-14 | Release date: | 2020-11-11 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
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7AO8
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![BU of 7ao8 by Molmil](/molmil-images/mine/7ao8) | Structure of the MTA1/HDAC1/MBD2 NURD deacetylase complex | Descriptor: | Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, Metastasis-associated protein MTA1, ... | Authors: | Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. | Deposit date: | 2020-10-14 | Release date: | 2020-11-11 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
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8EVI
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![BU of 8evi by Molmil](/molmil-images/mine/8evi) | CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations | Descriptor: | DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | Authors: | Lian, T, Guan, R, Bai, Y. | Deposit date: | 2022-10-20 | Release date: | 2023-11-01 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (2.64 Å) | Cite: | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha. Nat.Struct.Mol.Biol., 31, 2024
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5A5B
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![BU of 5a5b by Molmil](/molmil-images/mine/5a5b) | Structure of the 26S proteasome-Ubp6 complex | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | Authors: | Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F. | Deposit date: | 2015-06-17 | Release date: | 2015-07-22 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 112, 2015
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5MPB
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![BU of 5mpb by Molmil](/molmil-images/mine/5mpb) | 26S proteasome in presence of AMP-PNP (s3) | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. | Deposit date: | 2016-12-16 | Release date: | 2017-03-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6WKR
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![BU of 6wkr by Molmil](/molmil-images/mine/6wkr) | PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome | Descriptor: | DNA (314-MER), Histone H2A type 1, Histone H2B 1.1, ... | Authors: | Kasinath, V, Nogales, E, Beck, C, Sauer, P, Poepsel, S, Kosmatka, J, Faini, M, Toso, D, Aebersold, R. | Deposit date: | 2020-04-16 | Release date: | 2021-02-03 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. Science, 371, 2021
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5MPC
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![BU of 5mpc by Molmil](/molmil-images/mine/5mpc) | 26S proteasome in presence of BeFx (s4) | Descriptor: | 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B homolog, ... | Authors: | Wehmer, M, Rudack, T, Beck, F, Aufderheide, A, Pfeifer, G, Plitzko, J.M, Foerster, F, Schulten, K, Baumeister, W, Sakata, E. | Deposit date: | 2016-12-16 | Release date: | 2017-03-08 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.7 Å) | Cite: | Structural insights into the functional cycle of the ATPase module of the 26S proteasome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6K1P
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![BU of 6k1p by Molmil](/molmil-images/mine/6k1p) | The complex of ISWI-nucleosome in the ADP.BeF-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ... | Authors: | Yan, L.J, Wu, H, Li, X.M, Gao, N, Chen, Z.C. | Deposit date: | 2019-05-10 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling. Nat.Struct.Mol.Biol., 26, 2019
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6JYL
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![BU of 6jyl by Molmil](/molmil-images/mine/6jyl) | The crosslinked complex of ISWI-nucleosome in the ADP.BeF-bound state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (167-MER), ... | Authors: | Yan, L.J, Wu, H, Li, X.M, Gao, N, Chen, Z.C. | Deposit date: | 2019-04-26 | Release date: | 2019-05-29 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling. Nat.Struct.Mol.Biol., 26, 2019
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6R7N
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![BU of 6r7n by Molmil](/molmil-images/mine/6r7n) | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | Descriptor: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | Authors: | Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. | Deposit date: | 2019-03-29 | Release date: | 2019-08-28 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
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6R7I
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![BU of 6r7i by Molmil](/molmil-images/mine/6r7i) | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | Descriptor: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | Authors: | Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. | Deposit date: | 2019-03-28 | Release date: | 2019-08-28 | Last modified: | 2019-09-04 | Method: | ELECTRON MICROSCOPY (5.9 Å) | Cite: | Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
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8HXX
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![BU of 8hxx by Molmil](/molmil-images/mine/8hxx) | Cryo-EM structure of the histone deacetylase complex Rpd3S | Descriptor: | Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ... | Authors: | Cui, H, Wang, H. | Deposit date: | 2023-01-05 | Release date: | 2023-09-27 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
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9ANT
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![BU of 9ant by Molmil](/molmil-images/mine/9ant) | ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX | Descriptor: | ANTENNAPEDIA HOMEODOMAIN, DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*CP*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), ... | Authors: | Fraenkel, E, Pabo, C.O. | Deposit date: | 1998-07-02 | Release date: | 1998-10-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex. Nat.Struct.Biol., 5, 1998
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9ASS
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![BU of 9ass by Molmil](/molmil-images/mine/9ass) | |
8XOF
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![BU of 8xof by Molmil](/molmil-images/mine/8xof) | Cryo-EM structure of Lys05 bound GPR30-Gq complex structure | Descriptor: | G protein subunit q, G-protein coupled estrogen receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, H, Xu, P, Xu, H.E. | Deposit date: | 2024-01-01 | Release date: | 2024-04-10 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural and functional evidence that GPR30 is not a direct estrogen receptor. Cell Res., 34, 2024
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