6PVV
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![BU of 6pvv by Molmil](/molmil-images/mine/6pvv) | RNase A in complex with p5A | Descriptor: | ADENOSINE-5'-PENTAPHOSPHATE, Ribonuclease pancreatic | Authors: | Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. | Deposit date: | 2019-07-21 | Release date: | 2019-11-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A. J.Am.Chem.Soc., 141, 2019
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5EQO
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6QE9
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![BU of 6qe9 by Molmil](/molmil-images/mine/6qe9) | The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands | Descriptor: | Ribonuclease pancreatic, SULFATE ION, pentacoordinate Pt(II) compound | Authors: | Merlino, A, Ferraro, G. | Deposit date: | 2019-01-07 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Reaction with Proteins of a Five-Coordinate Platinum(II) Compound. Int J Mol Sci, 20, 2019
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5OLD
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5RSA
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5RAT
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4YGW
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![BU of 4ygw by Molmil](/molmil-images/mine/4ygw) | RNase S in complex with stabilized S peptide | Descriptor: | 1-hydroxypropan-2-one, Ribonuclease A C2, S-peptide: ACE-LYS-GLU-THR-ALA-ALA-HCS-LYS-PHE-GLU-HCS-GLN-HIS-MET-ASP-SER, ... | Authors: | Assem, N, Ferreira, D, Wolan, D.W, Dawson, P.E. | Deposit date: | 2015-02-26 | Release date: | 2015-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Acetone-Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling. Angew.Chem.Int.Ed.Engl., 54, 2015
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4WYZ
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![BU of 4wyz by Molmil](/molmil-images/mine/4wyz) | The crystal structure of the A109G mutant of RNase A in complex with 3'UMP | Descriptor: | 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic | Authors: | French, R.L, Gagne, D, Doucet, N, Simonovic, M. | Deposit date: | 2014-11-18 | Release date: | 2015-11-18 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23, 2015
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4WYN
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4X09
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![BU of 4x09 by Molmil](/molmil-images/mine/4x09) | Structure of human RNase 6 in complex with sulphate anions | Descriptor: | GLYCEROL, Ribonuclease K6, SULFATE ION | Authors: | Prats-Ejarque, G, Arranz-Trullen, J, Blanco, J.A, Pulido, D, Moussaoui, M, Boix, E. | Deposit date: | 2014-11-21 | Release date: | 2016-04-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.722 Å) | Cite: | The first crystal structure of human RNase 6 reveals a novel substrate-binding and cleavage site arrangement. Biochem.J., 473, 2016
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4WYP
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![BU of 4wyp by Molmil](/molmil-images/mine/4wyp) | The crystal structure of the A109G mutant of RNase A in complex with 5'AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic | Authors: | French, R.L, Gagne, D, Doucet, N, Simonovic, M. | Deposit date: | 2014-11-17 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.502 Å) | Cite: | Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23, 2015
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4X08
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![BU of 4x08 by Molmil](/molmil-images/mine/4x08) | Structure of H128N/ECP mutant in complex with sulphate anions at 1.34 Angstroms. | Descriptor: | Eosinophil cationic protein, SULFATE ION | Authors: | Blanco, J.A, Garcia, J.M, Salazar, V.A, Sanchez, D, Moussauoi, M, Boix, E. | Deposit date: | 2014-11-21 | Release date: | 2015-10-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Structure of H128N/ECP mutant in complex with sulphate anions at 1.34 Angstroms. To Be Published
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9EO8
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9RAT
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9RSA
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9EO5
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4K7M
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![BU of 4k7m by Molmil](/molmil-images/mine/4k7m) | Crystal structure of RNase S variant (K7C/Q11C) with bound mercury ions | Descriptor: | MERCURY (II) ION, Ribonuclease pancreatic, SULFATE ION | Authors: | Genz, M, Straeter, N. | Deposit date: | 2013-04-17 | Release date: | 2013-11-27 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Apo- and Metalated Thiolate containing RNase S as Structural Basis for the Design of Artificial Metalloenzymes by Peptide- Protein Complementation Z.Anorg.Allg.Chem., 639, 2013
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6XHF
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![BU of 6xhf by Molmil](/molmil-images/mine/6xhf) | Structure of Phenylalanyl-5'-O-adenosine phosphoramidate | Descriptor: | (2~{S})-2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]-3-phenyl-propanoic acid, CHLORIDE ION, Ribonuclease pancreatic | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid. Angew.Chem.Int.Ed.Engl., 59, 2020
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6XHE
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![BU of 6xhe by Molmil](/molmil-images/mine/6xhe) | Structure of beta-prolinyl 5'-O-adenosine phosphoramidate | Descriptor: | 5'-O-[(S)-[(3S)-3-carboxypyrrolidin-1-yl](hydroxy)phosphoryl]adenosine, ADENOSINE MONOPHOSPHATE, Ribonuclease pancreatic | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid. Angew.Chem.Int.Ed.Engl., 59, 2020
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6XHD
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![BU of 6xhd by Molmil](/molmil-images/mine/6xhd) | Structure of Prolinyl-5'-O-adenosine phosphoramidate | Descriptor: | (2~{S})-1-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]pyrrolidine-2-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, ... | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid. Angew.Chem.Int.Ed.Engl., 59, 2020
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6YO1
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![BU of 6yo1 by Molmil](/molmil-images/mine/6yo1) | Crystal structure of ribonuclease A solved by vanadium SAD phasing | Descriptor: | Ribonuclease pancreatic, URIDINE-2',3'-VANADATE | Authors: | El Omari, K, Mohamad, N, Bountra, K, Duman, R, Romano, M, Schlegel, K, Kwong, H, Mykhaylyk, V, Olesen, C.E, Moller, J.V, Bublitz, M, Beis, K, Wagner, A. | Deposit date: | 2020-04-14 | Release date: | 2020-11-04 | Last modified: | 2020-12-02 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Experimental phasing with vanadium and application to nucleotide-binding membrane proteins. Iucrj, 7, 2020
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4MXF
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4KXH
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![BU of 4kxh by Molmil](/molmil-images/mine/4kxh) | The X-ray crystal structure of a dimeric variant of human pancreatic ribonuclease | Descriptor: | CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... | Authors: | Pica, A, Merlino, A, Mazzarella, L, Sica, F. | Deposit date: | 2013-05-26 | Release date: | 2013-10-02 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase. Acta Crystallogr.,Sect.D, 69, 2013
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4L55
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6XVX
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