6XHF

Structure of Phenylalanyl-5'-O-adenosine phosphoramidate

Summary for 6XHF

• Entry DOI: 10.2210/pdb6xhf/pdb
• Descriptor: Ribonuclease pancreatic, (2~{S})-2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]-3-phenyl-propanoic acid, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: rnase a complex, amino acid release, prodrug, rna binding protein
• Biological source: Bos taurus (Bovine)
• Total number of polymer chains: 2
• Total formula weight: 28476.35

Authors

Pallan, P.S.,Egli, M. (deposition date: 2020-06-18, release date: 2021-03-17, Last modification date: 2023-10-18)

• Primary citation: Jovanovic, D.,Tremmel, P.,Pallan, P.S.,Egli, M.,Richert, C.; The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid.; Angew.Chem.Int.Ed.Engl., 59:20154-20160, 2020; PubMed: 32757352; DOI: 10.1002/anie.202008665

Experimental method

X-RAY DIFFRACTION (1.45 Å)