4WYZ
The crystal structure of the A109G mutant of RNase A in complex with 3'UMP
Summary for 4WYZ
Entry DOI | 10.2210/pdb4wyz/pdb |
Related | 4WYN 4WYP |
Descriptor | Ribonuclease pancreatic, 3'-URIDINEMONOPHOSPHATE (3 entities in total) |
Functional Keywords | conformational dynamics, hydrolase |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 2 |
Total formula weight | 28299.35 |
Authors | French, R.L.,Gagne, D.,Doucet, N.,Simonovic, M. (deposition date: 2014-11-18, release date: 2015-11-18, Last modification date: 2019-12-25) |
Primary citation | Gagne, D.,French, R.L.,Narayanan, C.,Simonovic, M.,Agarwal, P.K.,Doucet, N. Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23:2256-2266, 2015 Cited by PubMed: 26655472DOI: 10.1016/j.str.2015.10.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.449 Å) |
Structure validation
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