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1S50	X-ray structure of the GluR6 ligand binding core (S1S2A) in complex with glutamate at 1.65 A resolution Descriptor: GLUTAMIC ACID, Glutamate Receptor 6 Authors: Mayer, M.L. Deposit date: 2004-01-19 Release date: 2005-02-08 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005
1S7Y	Crystal structure of the GluR6 ligand binding core in complex with glutamate at 1.75 A resolution orthorhombic form Descriptor: GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 2 precursor Authors: Mayer, M.L. Deposit date: 2004-01-30 Release date: 2005-02-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005
1S9T	Crystal structure of the GLUR6 ligand binding core in complex with quisqualate at 1.8A resolution Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, CHLORIDE ION, Glutamate receptor, ... Authors: Mayer, M.L. Deposit date: 2004-02-05 Release date: 2005-02-08 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron, 45, 2005
1SD3	Crystal structure of the GLUR6 ligand binding core in complex with 2S,4R-4-methylglutamate at 1.8 Angstrom resolution Descriptor: 2S,4R-4-METHYLGLUTAMATE, Glutamate receptor, ionotropic kainate 2 Authors: Mayer, M.L. Deposit date: 2004-02-12 Release date: 2005-02-15 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. Neuron, 45, 2005
1SYI	X-RAY STRUCTURE OF THE Y702F MUTANT OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 2.1 A RESOLUTION. Descriptor: (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID, Glutamate receptor 2 Authors: Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S. Deposit date: 2004-04-01 Release date: 2005-03-22 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2. Mol.Pharmacol., 67, 2005
1SYH	X-RAY STRUCTURE OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 1.85 A RESOLUTION. Descriptor: (S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID, Glutamate receptor 2 Authors: Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S. Deposit date: 2004-04-01 Release date: 2005-03-22 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2. Mol.Pharmacol., 67, 2005
1TT1	CRYSTAL STRUCTURE OF THE GLUR6 LIGAND BINDING CORE IN COMPLEX WITH KAINATE 1.93 A RESOLUTION Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor, ionotropic kainate 2 Authors: Mayer, M.L. Deposit date: 2004-06-21 Release date: 2005-02-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005
1TXF	CRYSTAL STRUCTURE OF THE GLUR5 LIGAND BINDING CORE IN COMPLEX WITH GLUTAMATE AT 2.1 ANGSTROM RESOLUTION Descriptor: GLUTAMIC ACID, Glutamate receptor, ionotropic kainate 1 Authors: Mayer, M.L. Deposit date: 2004-07-04 Release date: 2005-02-08 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structures of the GluR5 and GluR6 ligand binding cores: Molecular mechanisms underlying kainate receptor selectivity Neuron, 45, 2005
1XHY	X-ray structure of the Y702F mutant of the GluR2 ligand-binding core (S1S2J) in complex with kainate at 1.85 A resolution Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor, SULFATE ION Authors: Frandsen, A, Pickering, D.S, Vestergaard, B, Kasper, C, Nielsen, B.B, Greenwood, J.R, Campiani, G, Gajhede, M, Schousboe, A, Kastrup, J.S. Deposit date: 2004-09-21 Release date: 2005-03-22 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2. Mol.Pharmacol., 67, 2005
1Y1M	Crystal structure of the NR1 ligand binding core in complex with cycloleucine Descriptor: 1-AMINOCYCLOPENTANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1 Authors: Inanobe, A, Gouaux, E. Deposit date: 2004-11-18 Release date: 2005-07-12 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005
1Y20	Crystal structure of the NR1 ligand-binding core in complex with ACPC Descriptor: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1 Authors: Inanobe, A, Gouaux, E. Deposit date: 2004-11-19 Release date: 2005-07-12 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005
1Y1Z	Crystal structure of the NR1 ligand binding core in complex with ACBC Descriptor: 1-AMINOCYCLOBUTANECARBOXLIC ACID, Glutamate [NMDA] receptor subunit zeta 1 Authors: Inanobe, A, Gouaux, E. Deposit date: 2004-11-19 Release date: 2005-07-12 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005
1WVJ	Exploring the GluR2 ligand-binding core in complex with the bicyclic AMPA analogue (S)-4-AHCP Descriptor: 3-(3-HYDROXY-7,8-DIHYDRO-6H-CYCLOHEPTA[D]ISOXAZOL-4-YL)-L-ALANINE, GLYCEROL, SULFATE ION, ... Authors: Nielsen, B.B, Pickering, D.S, Greenwood, J.R, Brehm, L, Gajhede, M, Schousboe, A, Kastrup, J.S. Deposit date: 2004-12-15 Release date: 2005-04-26 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP FEBS J., 272, 2005
1YAE	Structure of the Kainate Receptor Subunit GluR6 Agonist Binding Domain Complexed with Domoic Acid Descriptor: (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor, ... Authors: Nanao, M.H, Green, T, Stern-Bach, Y, Heinemann, S.F, Choe, S. Deposit date: 2004-12-17 Release date: 2005-02-01 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3.11 Å) Cite: Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid. Proc.Natl.Acad.Sci.USA, 102, 2005
1YCJ	Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate Descriptor: GLUTAMIC ACID, Ionotropic glutamate receptor 5, SULFATE ION Authors: Naur, P, Vestergaard, B, Skov, L.K, Egebjerg, J, Gajhede, M, Kastrup, J.S. Deposit date: 2004-12-22 Release date: 2005-02-01 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate Febs Lett., 579, 2005
2A5T	Crystal Structure Of The NR1/NR2A ligand-binding cores complex Descriptor: GLUTAMIC ACID, GLYCINE, N-methyl-D-aspartate receptor NMDAR1-4a subunit, ... Authors: Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E. Deposit date: 2005-06-30 Release date: 2005-11-15 Last modified: 2017-07-26 Method: X-RAY DIFFRACTION (2 Å) Cite: Subunit arrangement and function in NMDA receptors Nature, 438, 2005
2A5S	Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate Descriptor: GLUTAMIC ACID, N-methyl-D-aspartate receptor NMDAR2A subunit Authors: Furukawa, H, Singh, S.K, Mancusso, R, Gouaux, E. Deposit date: 2005-06-30 Release date: 2005-11-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Subunit arrangement and function in NMDA receptors Nature, 438, 2005
2AIX	X-ray structure of the GLUR2 ligand-binding core (S1S2J) in complex with (s)-thio-atpa at 2.2 a resolution. Descriptor: (S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-YL) PROPRIONIC ACID, Glutamate receptor 2 Authors: Kastrup, J.S. Deposit date: 2005-08-01 Release date: 2005-08-09 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Distinct kinetics of ionotropic glutamate receptor 2 splice variants characterized by fast agonist application and crystallization of a receptor-ligand complex. To be Published
2AL5	Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam Descriptor: 1-(4-METHOXYBENZOYL)-2-PYRROLIDINONE, 2-AMINO-3-(5-FLUORO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID, Glutamate receptor 2 Authors: Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M. Deposit date: 2005-08-04 Release date: 2005-10-25 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Mechanism of positive allosteric modulators acting on AMPA receptors. J.Neurosci., 25, 2005
2AL4	CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614. Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE, Glutamate receptor 2, ... Authors: Jin, R, Clark, S, Weeks, A.M, Dudman, J.T, Gouaux, E, Partin, K.M. Deposit date: 2005-08-04 Release date: 2005-10-25 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Mechanism of positive allosteric modulators acting on AMPA receptors. J.Neurosci., 25, 2005
2ANJ	Crystal Structure of the Glur2 Ligand Binding Core (S1S2J-Y450W) Mutant in Complex With the Partial Agonist Kainic Acid at 2.1 A Resolution Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2 Authors: Holm, M.M, Naur, P, Vestergaard, B, Geballe, M.T, Gajhede, M, Kastrup, J.S, Traynelis, S.F, Egebjerg, J. Deposit date: 2005-08-11 Release date: 2005-08-30 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A Binding Site Tyrosine Shapes Desensitization Kinetics and Agonist Potency at GluR2: a mutagenic, kinetic, and crystallographic study J.Biol.Chem., 280, 2005
2F35	Crystal Structure of the GluR5 Ligand Binding Core with UBP302 At 1.87 Angstroms Resolution Descriptor: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... Authors: Mayer, M.L. Deposit date: 2005-11-18 Release date: 2006-04-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J.Neurosci., 26, 2006
2F34	Crystal Structure of the GluR5 Ligand Binding Core Dimer with UBP310 At 1.74 Angstroms Resolution Descriptor: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHENE-3-YL-METHYL)-5-METHYLPYRIMIDINE-2,4-DIONE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... Authors: Mayer, M.L. Deposit date: 2005-11-18 Release date: 2006-04-04 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.74 Å) Cite: Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J.Neurosci., 26, 2006
2F36	Crystal Structure of the GluR5 Ligand Binding Core Dimer with Glutamate At 2.1 Angstroms Resolution Descriptor: GLUTAMATE RECEPTOR, IONOTROPIC KAINATE 1, GLUTAMIC ACID, ... Authors: Mayer, M.L. Deposit date: 2005-11-18 Release date: 2006-04-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J.Neurosci., 26, 2006
2GFE	Crystal structure of the GluR2 A476E S673D Ligand Binding Core Mutant at 1.54 Angstroms Resolution Descriptor: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION Authors: Mayer, M.L. Deposit date: 2006-03-21 Release date: 2006-08-22 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate. J.Neurosci., 26, 2006

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