8DK9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dk9 by Molmil](/molmil-images/mine/8dk9) | Sliding-clamp-DinX peptide | Descriptor: | ACETYL GROUP, AMINO GROUP, Beta sliding clamp, ... | Authors: | Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. | Deposit date: | 2022-07-05 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Interaction of sliding clamp with mycobacterial polymerases To Be Published
|
|
8DJQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8djq by Molmil](/molmil-images/mine/8djq) | Sliding-clamp-DnaE1 peptide | Descriptor: | ACETYL GROUP, AMINO GROUP, Beta sliding clamp, ... | Authors: | Kapur, M.K, Gray, O.J, Honzatko, R.H, Nelson, S.N. | Deposit date: | 2022-07-01 | Release date: | 2023-01-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Interaction of the sliding clamp with mycobacterial polymerases To Be Published
|
|
7SH2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sh2 by Molmil](/molmil-images/mine/7sh2) | Structure of the yeast Rad24-RFC loader bound to DNA and the open 9-1-1 clamp | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2021-10-07 | Release date: | 2022-03-23 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp. Nat.Struct.Mol.Biol., 29, 2022
|
|
7SGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sgz by Molmil](/molmil-images/mine/7sgz) | Structure of the yeast Rad24-RFC loader bound to DNA and the closed 9-1-1 clamp | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ... | Authors: | Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. | Deposit date: | 2021-10-07 | Release date: | 2022-03-23 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.17 Å) | Cite: | DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp. Nat.Struct.Mol.Biol., 29, 2022
|
|
7Z6H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z6h by Molmil](/molmil-images/mine/7z6h) | Structure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp | Descriptor: | Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1,Cell cycle checkpoint protein RAD17, Checkpoint protein HUS1, ... | Authors: | Day, M, Oliver, A.W, Pearl, L.H. | Deposit date: | 2022-03-11 | Release date: | 2022-05-04 | Last modified: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (3.59 Å) | Cite: | Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction. Nucleic Acids Res., 50, 2022
|
|
4S3I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4s3i by Molmil](/molmil-images/mine/4s3i) | |
4RKI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rki by Molmil](/molmil-images/mine/4rki) | |
3D1F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d1f by Molmil](/molmil-images/mine/3d1f) | Crystal structure of E. coli sliding clamp (beta) bound to a polymerase III peptide | Descriptor: | 2-[3,6-bis(dimethylamino)xanthen-9-yl]-5-methanoyl-benzoate, DI(HYDROXYETHYL)ETHER, DNA polymerase III subunit beta, ... | Authors: | Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M. | Deposit date: | 2008-05-05 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
1B8H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1b8h by Molmil](/molmil-images/mine/1b8h) | SLIDING CLAMP, DNA POLYMERASE | Descriptor: | DNA POLYMERASE PROCESSIVITY COMPONENT, DNA POLYMERASE fragment | Authors: | Shamoo, Y, Steitz, T.A. | Deposit date: | 1999-02-01 | Release date: | 1999-02-09 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex. Cell(Cambridge,Mass.), 99, 1999
|
|
3D1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d1g by Molmil](/molmil-images/mine/3d1g) | Structure of a small molecule inhibitor bound to a DNA sliding clamp | Descriptor: | DNA polymerase III subunit beta, [(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid | Authors: | Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M. | Deposit date: | 2008-05-05 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
3D1E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d1e by Molmil](/molmil-images/mine/3d1e) | Crystal structure of E. coli sliding clamp (beta) bound to a polymerase II peptide | Descriptor: | DNA polymerase III subunit beta, decamer from polymerase II C-terminal | Authors: | Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M. | Deposit date: | 2008-05-05 | Release date: | 2008-07-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
7KC0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kc0 by Molmil](/molmil-images/mine/7kc0) | Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ... | Authors: | Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E. | Deposit date: | 2020-10-04 | Release date: | 2020-12-02 | Last modified: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
1A5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1a5t by Molmil](/molmil-images/mine/1a5t) | CRYSTAL STRUCTURE OF THE DELTA PRIME SUBUNIT OF THE CLAMP-LOADER COMPLEX OF ESCHERICHIA COLI DNA POLYMERASE III | Descriptor: | DELTA PRIME, ZINC ION | Authors: | Guenther, B, Onrust, R, Sali, A, O'Donnell, M, Kuriyan, J. | Deposit date: | 1998-02-18 | Release date: | 1998-05-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the delta' subunit of the clamp-loader complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 91, 1997
|
|
1JQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jqj by Molmil](/molmil-images/mine/1jqj) | Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of the beta-delta complex | Descriptor: | DNA polymerase III, beta chain, delta subunit | Authors: | Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J. | Deposit date: | 2001-08-07 | Release date: | 2001-11-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 106, 2001
|
|
7DTA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7dta by Molmil](/molmil-images/mine/7dta) | |
1JQL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jql by Molmil](/molmil-images/mine/1jql) | Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of E. coli DNA Polymerase III: Structure of beta-delta (1-140) | Descriptor: | DNA Polymerase III, BETA CHAIN, DELTA SUBUNIT | Authors: | Jeruzalmi, D, Yurieva, O, Zhao, Y, Young, M, Stewart, J, Hingorani, M, O'Donnell, M, Kuriyan, J. | Deposit date: | 2001-08-07 | Release date: | 2001-09-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 106, 2001
|
|
8GJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gj1 by Molmil](/molmil-images/mine/8gj1) | |
8GIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8giy by Molmil](/molmil-images/mine/8giy) | E. coli clamp loader with closed clamp | Descriptor: | Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ... | Authors: | Oakley, A.J, Xu, Z.-Q, Dixon, N.E. | Deposit date: | 2023-03-14 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural characterisation of the complete cycle of sliding clamp loading in E. coli To Be Published
|
|
8GJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gj0 by Molmil](/molmil-images/mine/8gj0) | |
1SXJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sxj by Molmil](/molmil-images/mine/1sxj) | Crystal Structure of the Eukaryotic Clamp Loader (Replication Factor C, RFC) Bound to the DNA Sliding Clamp (Proliferating Cell Nuclear Antigen, PCNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Activator 1 37 kDa subunit, Activator 1 40 kDa subunit, ... | Authors: | Bowman, G.D, O'Donnell, M, Kuriyan, J. | Deposit date: | 2004-03-30 | Release date: | 2004-06-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex. Nature, 429, 2004
|
|
3BEP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bep by Molmil](/molmil-images/mine/3bep) | Structure of a sliding clamp on DNA | Descriptor: | 1-(3-hydroxypropyl)-2-{(1E,3E,5E)-5-[1-(3-hydroxypropyl)-3,3-dimethyl-1,3-dihydro-2H-indol-2-ylidene]penta-1,3-dien-1-y l}-3,3-dimethyl-3H-indolium, DNA (5'-D(*DTP*DTP*DTP*DTP*DAP*DTP*DAP*DCP*DGP*DAP*DTP*DGP*DGP*DG)-3'), DNA (5'-D(P*DCP*DCP*DCP*DAP*DTP*DCP*DGP*DTP*DAP*DT)-3'), ... | Authors: | Georgescu, R.E, Kim, S.S, Yurieva, O, Kuriyan, J, Kong, X.-P, O'Donnell, M. | Deposit date: | 2007-11-19 | Release date: | 2008-01-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structure of a sliding clamp on DNA Cell(Cambridge,Mass.), 132, 2008
|
|
8GIZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8giz by Molmil](/molmil-images/mine/8giz) | E. coli clamp loader with open clamp | Descriptor: | Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ... | Authors: | Oakley, A.J, Xu, Z.-Q, Dixon, N.E. | Deposit date: | 2023-03-14 | Release date: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural characterisation of the complete cycle of sliding clamp loading in E. coli To Be Published
|
|
8GJ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gj2 by Molmil](/molmil-images/mine/8gj2) | |
1OK7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ok7 by Molmil](/molmil-images/mine/1ok7) | A Conserved protein binding-site on Bacterial Sliding Clamps | Descriptor: | DNA POLYMERASE III, DNA POLYMERASE IV | Authors: | Burnouf, D.Y, Olieric, V, Wagner, J, Fujii, S, Reinbolt, J, Fuchs, R.P.P, Dumas, P. | Deposit date: | 2003-07-18 | Release date: | 2004-07-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and Biochemical Analysis of Sliding Clamp/Ligand Interactions Suggest a Competition between Replicative and Translesion DNA Polymerases J.Mol.Biol., 335, 2004
|
|
3U61
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3u61 by Molmil](/molmil-images/mine/3u61) | Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... | Authors: | Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. | Deposit date: | 2011-10-11 | Release date: | 2012-01-04 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
|
|