7SGZ

Structure of the yeast Rad24-RFC loader bound to DNA and the closed 9-1-1 clamp

Summary for 7SGZ

• Entry DOI: 10.2210/pdb7sgz/pdb
• EMDB information: 25121 25122
• Descriptor: Checkpoint protein RAD24, Crick strand, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (14 entities in total)
• Functional Keywords: dna damage repair, rad24-rfc, 9-1-1 clamp, dna clamp, alternative clamp loader, dna damage signaling, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 10
• Total formula weight: 415760.75

Authors

Zheng, F.,Georgescu, R.,Yao, Y.N.,O'Donnell, M.E.,Li, H. (deposition date: 2021-10-07, release date: 2022-03-23, Last modification date: 2022-04-27)

• Primary citation: Zheng, F.,Georgescu, R.E.,Yao, N.Y.,O'Donnell, M.E.,Li, H.; DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp.; Nat.Struct.Mol.Biol., 29:376-385, 2022; PubMed: 35314830; DOI: 10.1038/s41594-022-00742-6

Experimental method

ELECTRON MICROSCOPY (3.17 Å)