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7QYD
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BU of 7qyd by Molmil
mosquitocidal Cry11Ba determined at pH 6.5 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Ba
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P, Sawaya, M.R, Schibrowsky, N.A, Cascio, D, Rodriguez, J.A.
Deposit date:2022-01-28
Release date:2022-07-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX4
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BU of 7qx4 by Molmil
mosquitocidal Cry11Aa determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX6
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BU of 7qx6 by Molmil
mosquitocidal Cry11Aa-E583Q determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX5
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BU of 7qx5 by Molmil
mosquitocidal Cry11Aa-Y449F determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
7QX7
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BU of 7qx7 by Molmil
mosquitocidal Cry11Aa-F17Y determined at pH 7 from naturally-occurring nanocrystals by Serial femtosecond crystallography
Descriptor: Pesticidal crystal protein Cry11Aa
Authors:De Zitter, E, Tetreau, G, Andreeva, E.A, Coquelle, N, Colletier, J.-P.
Deposit date:2022-01-26
Release date:2022-07-27
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals.
Nat Commun, 13, 2022
5LTY
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BU of 5lty by Molmil
Homeobox transcription factor CDX2 bound to methylated DNA
Descriptor: DNA (5'-D(P*GP*GP*AP*GP*GP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*CP*CP*TP*CP*C)-3'), Homeobox protein CDX-2
Authors:Morgunova, E, Popov, A, Taipale, J.
Deposit date:2016-09-07
Release date:2017-05-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Impact of cytosine methylation on DNA binding specificities of human transcription factors.
Science, 356, 2017
4YJN
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BU of 4yjn by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1639
Descriptor: 5-amino-1-tert-butyl-3-[2-(cyclobutyloxy)quinolin-6-yl]-1H-pyrazole-4-carboxamide, Calmodulin-domain protein kinase 1
Authors:Merritt, E.A.
Deposit date:2015-03-03
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1.
Acs Med.Chem.Lett., 6, 2015
8C6J
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BU of 8c6j by Molmil
Human spliceosomal PM5 C* complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Dybkov, O, Kastner, B, Luehrmann, R.
Deposit date:2023-01-12
Release date:2023-07-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.
Sci Adv, 9, 2023
7SR6
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BU of 7sr6 by Molmil
Human Endogenous Retrovirus (HERV-K) reverse transcriptase ternary complex with dsDNA template Primer and dNTP
Descriptor: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, ...
Authors:Baldwin, E.T, Nichols, C.
Deposit date:2021-11-08
Release date:2022-07-20
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Human endogenous retrovirus-K (HERV-K) reverse transcriptase (RT) structure and biochemistry reveals remarkable similarities to HIV-1 RT and opportunities for HERV-K-specific inhibition.
Proc.Natl.Acad.Sci.USA, 119, 2022
5N8J
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BU of 5n8j by Molmil
CRYSTAL STRUCTURE OF STREPTAVIDIN WITH PEPTIDE D-amino acid containing peptide GyGlanvdessG
Descriptor: GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY, ISOPROPYL ALCOHOL, Streptavidin
Authors:Lyamichev, V, Goodrich, L, Sullivan, E, Bannen, R, Benz, J, Albert, T, Patel, J.
Deposit date:2017-02-23
Release date:2017-10-25
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target.
Sci Rep, 7, 2017
5HLF
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BU of 5hlf by Molmil
STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE In COMPLEX WITH A 38-MER HAIRPIN TEMPLATE-PRIMER DNA APTAMER AND AN ALPHA-CARBOXYPHOSPHONATE INHIBITOR
Descriptor: DNA (38-MER), GLYCEROL, HIV-1 REVERSE TRANSCRIPTASE P51 SUBUNIT, ...
Authors:Das, K, Arnold, E.
Deposit date:2016-01-15
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Exploring the role of the alpha-carboxyphosphonate moiety in the HIV-RT activity of alpha-carboxy nucleoside phosphonates.
Org.Biomol.Chem., 14, 2016
6NFJ
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BU of 6nfj by Molmil
Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide
Descriptor: Beta-klotho, Fibroblast growth factor 19, Nanobody 30
Authors:Kuzina, E, Schlessinger, J, Lee, S.
Deposit date:2018-12-20
Release date:2019-04-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structures of ligand-occupied beta-Klotho complexes reveal a molecular mechanism underlying endocrine FGF specificity and activity.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6NJU
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BU of 6nju by Molmil
Mouse endonuclease G mutant H97A bound to A-DNA
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DNA (5'-D(CCGGCGCCGG)-3'), ...
Authors:Vander Zanden, C.M, Ho, E.N, Czarny, R.S, Robertson, A.B, Ho, P.S.
Deposit date:2019-01-04
Release date:2020-01-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function.
Nucleic Acids Res., 48, 2020
6O0J
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BU of 6o0j by Molmil
M.tb MenD with ThDP and Inhibitor bound
Descriptor: 1,4-dihydroxy-2-naphthoic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, ACETATE ION, ...
Authors:Johnston, J.M, Bashiri, G, Bulloch, E.M.M, Jirgis, E.M.N, Nigon, L.V, Chuang, H, Ho, N.A.T, Baker, E.N.
Deposit date:2019-02-16
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Allosteric regulation of menaquinone (vitamin K2) biosynthesis in the human pathogenMycobacterium tuberculosis.
J.Biol.Chem., 295, 2020
4TXD
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BU of 4txd by Molmil
Crystal structure of Thermofilum pendens Csc2
Descriptor: Csc2, ZINC ION
Authors:Hrle, A, Conti, E.
Deposit date:2014-07-03
Release date:2014-08-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.818 Å)
Cite:Structural analyses of the CRISPR protein Csc2 reveal the RNA-binding interface of the type I-D Cas7 family.
Rna Biol., 11, 2014
4TZI
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BU of 4tzi by Molmil
Structure of unliganded Lyn SH2 domain
Descriptor: Tyrosine-protein kinase Lyn
Authors:Wybenga-Groot, L.E.
Deposit date:2014-07-10
Release date:2015-01-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity.
Mol.Cell Proteomics, 14, 2015
4U28
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BU of 4u28 by Molmil
Crystal structure of apo Phosphoribosyl isomerase A from Streptomyces sviceus ATCC 29083
Descriptor: PHOSPHATE ION, Phosphoribosyl isomerase A
Authors:Chang, C, Verduzco-Castro, E.A, Endres, M, Barona-Gomez, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop.
Biochem. J., 473, 2016
4U7E
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BU of 4u7e by Molmil
The crystal structure of the complex of LIP5 NTD and IST1 MIM
Descriptor: IST1 homolog, Vacuolar protein sorting-associated protein VTA1 homolog
Authors:Guo, E.Z, Xu, Z.
Deposit date:2014-07-30
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
8F2P
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BU of 8f2p by Molmil
Nef SF2 dimerization mutant bound to Hck SH3
Descriptor: C-terminal core protein, Tyrosine-protein kinase HCK
Authors:Thomas, C.E, Alvarado, J.J, Smithgall, T.E.
Deposit date:2022-11-08
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Neutron Reflectometry and Molecular Simulations Demonstrate HIV-1 Nef Homodimer Formation on Model Lipid Bilayers.
J.Mol.Biol., 435, 2023
8F94
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BU of 8f94 by Molmil
Structure of an alternating AT 16-mer: 5'-GCTGGATATATCCAGC-3
Descriptor: CALCIUM ION, DNA 16-mer
Authors:Terrell, J.R, Ogbonna, E.N, Wilson, W.D.
Deposit date:2022-11-23
Release date:2023-02-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
8EGX
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BU of 8egx by Molmil
Complex of Fat4(EC1-4) bound to Dchs1(EC1-4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Medina, E, Luca, V.C.
Deposit date:2022-09-13
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.688 Å)
Cite:Structure of the planar cell polarity cadherins Fat4 and Dachsous1.
Nat Commun, 14, 2023
8F1S
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BU of 8f1s by Molmil
A benzimidazole (DB1476) sequence-specific recognition of 5'-CGCAAAAAAGCG-3' in A-orientation
Descriptor: 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*TP*TP*TP*TP*GP*CP*G)-3'), ...
Authors:Ogbonna, E.N, Wilson, W.D.
Deposit date:2022-11-06
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
4WG3
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BU of 4wg3 by Molmil
Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1610
Descriptor: 3-(7-ethoxynaphthalen-2-yl)-1-(2-methylpropyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:Merritt, E.A.
Deposit date:2014-09-17
Release date:2014-10-15
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1610
to be published
8F1V
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BU of 8f1v by Molmil
A benzimidazole (DB1476) sequence-specific recognition of 5'-CGCAAAAAAGCG-3' in B-orientation
Descriptor: 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*AP*AP*AP*AP*AP*AP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*TP*TP*TP*TP*TP*TP*GP*CP*G)-3'), ...
Authors:Ogbonna, E.N, Wilson, W.D.
Deposit date:2022-11-06
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
8F2Y
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BU of 8f2y by Molmil
Structure of an alternating AT dodecamer: 5'-CGCGATATCGCG-3
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*TP*AP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Ogbonna, E.N, Wilson, W.D.
Deposit date:2022-11-09
Release date:2023-02-22
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023

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