5P0S
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1L8Y
| Solution structure of HMG box 5 in human upstream binding factor | Descriptor: | upstream binding factor 1 | Authors: | Yang, W, Xu, Y, Wu, J, Zeng, W, Shi, Y. | Deposit date: | 2002-03-22 | Release date: | 2002-06-05 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure and DNA binding property of the fifth HMG box domain in comparison with the first HMG box domain in human upstream binding factor Biochemistry, 42, 2003
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1L3R
| Crystal Structure of a Transition State Mimic of the Catalytic Subunit of cAMP-dependent Protein Kinase | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ... | Authors: | Madhusudan, Akamine, P, Xuong, N.-H, Taylor, S.S. | Deposit date: | 2002-02-28 | Release date: | 2002-03-20 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase. Nat.Struct.Biol., 9, 2002
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4F38
| Crystal structure of geranylgeranylated RhoA in complex with RhoGDI in its active GPPNHP-bound form | Descriptor: | GERAN-8-YL GERAN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Guo, Z, Tnimov, Z, Alexandrov, K. | Deposit date: | 2012-05-09 | Release date: | 2012-05-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Quantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDI. J.Biol.Chem., 287, 2012
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6RFQ
| Cryo-EM structure of a respiratory complex I assembly intermediate with NDUFAF2 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | Authors: | Parey, K, Vonck, J. | Deposit date: | 2019-04-16 | Release date: | 2019-12-11 | Last modified: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease. Sci Adv, 5, 2019
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6RS6
| X-ray crystal structure of LsAA9B | Descriptor: | AA9, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Frandsen, K.E.H, Tovborg, M, Poulsen, J.C.N, Johansen, K.S, Lo Leggio, L. | Deposit date: | 2019-05-21 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases. J.Biol.Chem., 294, 2019
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1HLS
| NMR STRUCTURE OF THE HUMAN INSULIN-HIS(B16) | Descriptor: | INSULIN | Authors: | Ludvigsen, S, Kaarsholm, N.C. | Deposit date: | 1995-06-28 | Release date: | 1995-09-15 | Last modified: | 2017-11-29 | Method: | SOLUTION NMR | Cite: | High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr-->His, as determined by nuclear magnetic resonance spectroscopy. Biochemistry, 33, 1994
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6S6Y
| X-ray crystal structure of the formyltransferase/hydrolase complex (FhcABCD) from Methylorubrum extorquens in complex with methylofuran | Descriptor: | (2~{S})-3-[4-[[5-(aminomethyl)furan-3-yl]methoxy]phenyl]-2-(methylamino)propanoic acid, 1,2-ETHANEDIOL, AMINO GROUP, ... | Authors: | Wagner, T, Hemmann, J.L, Shima, S, Vorholt, J. | Deposit date: | 2019-07-04 | Release date: | 2019-12-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Methylofuran is a prosthetic group of the formyltransferase/hydrolase complex and shuttles one-carbon units between two active sites. Proc.Natl.Acad.Sci.USA, 116, 2019
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6RGO
| Complex of KlAtg21 with coiled-coil of AgAtg16 | Descriptor: | Autophagy protein 16, Autophagy-related protein 21 | Authors: | Thumm, M, Neumann, P. | Deposit date: | 2019-04-17 | Release date: | 2020-05-13 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.701 Å) | Cite: | Atg21 organizes Atg8 lipidation at the contact of the vacuole with the phagophore. Autophagy, 2020
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7YTE
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7YTD
| Cryo-EM structure of four human FcmR bound to IgM-Fc/J | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | Authors: | Li, Y, Shen, H, Xiao, J. | Deposit date: | 2022-08-14 | Release date: | 2023-02-01 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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7YTC
| Cryo-EM structure of human FcmR bound to IgM-Fc/J | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | Authors: | Li, Y, Shen, H, Xiao, J. | Deposit date: | 2022-08-14 | Release date: | 2023-02-01 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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7YSG
| Cryo-EM structure of human FcmR bound to sIgM | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | Authors: | Li, Y, Shen, H, Xiao, J. | Deposit date: | 2022-08-12 | Release date: | 2023-02-01 | Last modified: | 2023-05-03 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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6RQ4
| Inhibitor of ERK2 | Descriptor: | 6,6-dimethyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5-(2-morpholin-4-ylethyl)thieno[2,3-c]pyrrol-4-one, Mitogen-activated protein kinase 1, SULFATE ION | Authors: | O'Reilly, M. | Deposit date: | 2019-05-15 | Release date: | 2019-12-04 | Last modified: | 2020-02-19 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2. Mol.Cancer Ther., 19, 2020
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7YON
| Complex structure of Neuropeptide Y Y2 receptor in complex with PYY(3-36) and Gi | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Kang, H, Park, C, Kim, J, Choi, H.-J. | Deposit date: | 2022-08-01 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
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7YOO
| Complex structure of Neuropeptide Y Y2 receptor in complex with NPY and Gi | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Kang, H, Park, C, Kim, J, Choi, H.-J. | Deposit date: | 2022-08-01 | Release date: | 2023-03-22 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis for Y2 receptor-mediated neuropeptide Y and peptide YY signaling. Structure, 31, 2023
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6RS7
| X-ray crystal structure of LsAA9B (deglycosylated form) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AA9, ... | Authors: | Frandsen, K.E.H, Tovborg, M, Poulsen, J.C.N, Johansen, K.S, Lo Leggio, L. | Deposit date: | 2019-05-21 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases. J.Biol.Chem., 294, 2019
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7YV4
| Crystal structure of human UCHL3 in complex with Farrerol | Descriptor: | (2~{S})-2-(4-hydroxyphenyl)-6,8-dimethyl-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, Ubiquitin carboxyl-terminal hydrolase isozyme L3 | Authors: | Mao, Z.Y, Xu, X.J, Zhang, W.T. | Deposit date: | 2022-08-18 | Release date: | 2023-04-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Farrerol directly activates the deubiqutinase UCHL3 to promote DNA repair and reprogramming when mediated by somatic cell nuclear transfer. Nat Commun, 14, 2023
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6RFR
| Cryo-EM structure of respiratory complex I from Yarrowia lipolytica at 3.2 A resolution | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | Authors: | Parey, K, Vonck, J. | Deposit date: | 2019-04-16 | Release date: | 2019-12-11 | Last modified: | 2021-06-02 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease. Sci Adv, 5, 2019
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7YQB
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6RS9
| X-ray crystal structure of LsAA9B (xylotetraose soak) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AA9, BICINE, ... | Authors: | Frandsen, K.E.H, Tovborg, M, Poulsen, J.C.N, Johansen, K.S, Lo Leggio, L. | Deposit date: | 2019-05-21 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases. J.Biol.Chem., 294, 2019
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6RNK
| Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex with a nanobody and antagonist NF-56-EJ40. | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[2-[[3-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]carbonylamino]phenyl]ethanoic acid, GLYCEROL, ... | Authors: | Haffke, M, Jaakola, V.-P. | Deposit date: | 2019-05-08 | Release date: | 2019-08-14 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structural basis of species-selective antagonist binding to the succinate receptor. Nature, 574, 2019
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8SH5
| Crystal structure of 3'cap-independent translation enhancers (CITE) from Pea enation mosaic virus RNA 2 (PEMV2) with Fab BL3-6K170A | Descriptor: | Fab BL3-6K170A heavy chain, Fab BL3-6K170A light chain, RNA (88-MER) | Authors: | Lewicka, A, Roman, C, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2023-04-13 | Release date: | 2023-08-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structure of a cap-independent translation enhancer RNA. Nucleic Acids Res., 51, 2023
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6RFS
| Cryo-EM structure of a respiratory complex I mutant lacking NDUFS4 | Descriptor: | Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I), FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Parey, K, Vonck, J. | Deposit date: | 2019-04-16 | Release date: | 2019-12-11 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (4.04 Å) | Cite: | High-resolution cryo-EM structures of respiratory complex I: Mechanism, assembly, and disease. Sci Adv, 5, 2019
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6RS8
| X-ray crystal structure of LsAA9B (transition metals soak) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Frandsen, K.E.H, Tovborg, M, Poulsen, J.C.N, Johansen, K.S, Lo Leggio, L. | Deposit date: | 2019-05-21 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Insights into an unusual Auxiliary Activity 9 family member lacking the histidine brace motif of lytic polysaccharide monooxygenases. J.Biol.Chem., 294, 2019
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