4F38

Crystal structure of geranylgeranylated RhoA in complex with RhoGDI in its active GPPNHP-bound form

Summary for 4F38

Entry DOI	10.2210/pdb4f38/pdb
Descriptor	Transforming protein RhoA, Rho GDP-dissociation inhibitor 1, GERAN-8-YL GERAN, ... (6 entities in total)
Functional Keywords	rhoa, rhogdi, active gppnhp bound form, cell cycle-chaperone complex, cell cycle/chaperone
Biological source	Mus musculus (mouse) More
Total number of polymer chains	2
Total formula weight	46218.89
Authors	Guo, Z.,Tnimov, Z.,Alexandrov, K. (deposition date: 2012-05-09, release date: 2012-05-23, Last modification date: 2023-11-08)
Primary citation	Tnimov, Z.,Guo, Z.,Gambin, Y.,Nguyen, U.T.,Wu, Y.W.,Abankwa, D.,Stigter, A.,Collins, B.M.,Waldmann, H.,Goody, R.S.,Alexandrov, K. Quantitative Analysis of Prenylated RhoA Interaction with Its Chaperone, RhoGDI. J.Biol.Chem., 287:26549-26562, 2012 Cited by PubMed: 22628549 DOI: 10.1074/jbc.M112.371294 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation