PDB: 36840 resultsInfo pagesStatus searchChemie searchBIRD

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4NNT	Crystal structure of FABP4 in complex with novel inhibitor Descriptor: 2,4,6-tri(propan-2-yl)benzoic acid, Fatty acid-binding protein, adipocyte Authors: Liu, Q.F, Chen, T.T, Xu, Y.C. Deposit date: 2013-11-19 Release date: 2014-11-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.53 Å) Cite: The complex structure of FABP4 with novel inhibitors To be Published
8GQ1	HyHEL10 Fab complexed with hen egg lysozyme carrying arginine cluster in framework region of light chain. Descriptor: Heavy Chain of HyHel10 Antibody Fragment (Fab), Light Chain of HyHel10 Antibody Fragment (Fab), Lysozyme C, ... Authors: Matsuura, H, Hirata, K, Sakai, N, Nakakido, M, Tsumoto, K. Deposit date: 2022-08-28 Release date: 2023-08-30 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.13 Å) Cite: Arginine cluster introduction on framework region in anti-lysozyme antibody improved association rate constant by changing conformational diversity of CDR loops. Protein Sci., 32, 2023
5WDQ	H-Ras mutant L120A bound to GMP-PNP at 100K Descriptor: ACETATE ION, CALCIUM ION, GTPase HRas, ... Authors: Bandaru, P, Gee, C.L, Kuriyan, J. Deposit date: 2017-07-05 Release date: 2017-07-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.25 Å) Cite: Deconstruction of the Ras switching cycle through saturation mutagenesis. Elife, 6, 2017
8GH6	Bombyx mori R2 retrotransposon initiating target-primed reverse transcription Descriptor: 28S DNA bottom strand, 3' side, 5' side (priming strand), ... Authors: Wilkinson, M.E, Zhang, F. Deposit date: 2023-03-09 Release date: 2023-04-05 Last modified: 2023-08-16 Method: ELECTRON MICROSCOPY (3.08 Å) Cite: Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription. Science, 380, 2023
8GN7	structure of human connexin 40.1 intercellular gap junction channel by cryoEM Descriptor: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, Gap junction delta-4 protein, ... Authors: Zhang, H, Wang, D.P. Deposit date: 2022-08-23 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3 Å) Cite: structure of human connexin 40.1 intercellular gap junction channel by cryoEM To Be Published
4NSH	Carboplatin binding to HEWL in 0.2M NH4SO4, 0.1M NaAc in 25% PEG 4000 at pH 4.6 Descriptor: ACETATE ION, DIMETHYL SULFOXIDE, Lysozyme C, ... Authors: Tanley, S.W.M, Diederichs, K, Kroon-Batenburg, L.M.J, Levy, C, Schreurs, A.M.M, Helliwell, J.R. Deposit date: 2013-11-28 Release date: 2014-10-15 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Carboplatin binding to histidine. Acta Crystallogr F Struct Biol Commun, 70, 2014
8GNB	structure of human connexin 40.1 side-by-side decamer channel by cryoEM Descriptor: Gap junction delta-4 protein Authors: Zhang, H, Wang, D.P. Deposit date: 2022-08-23 Release date: 2023-08-30 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: structure of human connexin 40.1 side-by-side decamer channel by cryoEM To Be Published
5WHD	Crystal structure of KRas G12V/D38P, bound to GDP Descriptor: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE Authors: Shim, S.Y, McGee, J.H, Lee, S.-J, Verdine, G.L. Deposit date: 2017-07-16 Release date: 2018-01-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.641 Å) Cite: Exceptionally high-affinity Ras binders that remodel its effector domain. J. Biol. Chem., 293, 2018
6BXU	Crystal Structure of Mouse Protocadherin-15 EC5-7 I582T Descriptor: CALCIUM ION, Protocadherin-15 Authors: Neel, B.L, Sotomayor, M. Deposit date: 2017-12-19 Release date: 2018-12-26 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.79 Å) Cite: Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception. Proc.Natl.Acad.Sci.USA, 2020
4NKY	Human steroidogenic cytochrome P450 17A1 mutant A105L with substrate 17alpha-hydroxyprogesterone Descriptor: (9beta)-17-hydroxypregn-4-ene-3,20-dione, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase Authors: Scott, E.E, Petrunak, E.M. Deposit date: 2013-11-13 Release date: 2014-10-22 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Structures of Human Steroidogenic Cytochrome P450 17A1 with Substrates. J.Biol.Chem., 289, 2014
4NCT	Human DYRK1A in complex with PKC412 Descriptor: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, PKC412 Authors: Alexeeva, M.O, Rothweiler, U. Deposit date: 2013-10-25 Release date: 2015-04-01 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.597 Å) Cite: The structure of a dual-specificity tyrosine phosphorylation-regulated kinase 1A-PKC412 complex reveals disulfide-bridge formation with the anomalous catalytic loop HRD(HCD) cysteine. Acta Crystallogr.,Sect.D, 71, 2015
6C4S	Human cSrc SH3 Domain in complex with Choline Kinase fragment 60-69 Descriptor: Proto-oncogene tyrosine-protein kinase Src,cSrc SH3 Domain, ZINC ION Authors: Kall, S.L, Lavie, A. Deposit date: 2018-01-12 Release date: 2019-01-23 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase. Sci Rep, 9, 2019
6C4W	Structure of the yeast Pichia membranifaciens cytochrome c Descriptor: HEME C, cytochrome c Authors: McPherson, A. Deposit date: 2018-01-13 Release date: 2018-02-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Characterization of two crystal forms of cytochrome c from Valida membranifaciens to be published
5WJQ	mouseZFP568-ZnF2-11 in complex with DNA Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (28-MER), ZINC ION, ... Authors: Patel, A, Cheng, X. Deposit date: 2017-07-24 Release date: 2018-03-07 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.794 Å) Cite: DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins. Cell, 173, 2018
4NNS	Crystal structure of FABP4 in complex with novel inhibitor Descriptor: 2,4,6-tri(propan-2-yl)benzenesulfonic acid, Fatty acid-binding protein, adipocyte Authors: Liu, Q.F, Chen, T.T, Xu, Y.C. Deposit date: 2013-11-19 Release date: 2014-11-19 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.53 Å) Cite: The complex structure of FABP4 with novel inhibitors To be Published
5YVA	Structure of CaMKK2 in complex with CKI-010 Descriptor: 3-(1H-tetrazol-5-yl)-10lambda~6~-thioxanthene-9,10,10-trione, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... Authors: Niwa, H, Handa, N, Yokoyama, S. Deposit date: 2017-11-24 Release date: 2018-12-05 Last modified: 2020-06-10 Method: X-RAY DIFFRACTION (2.574 Å) Cite: Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99, 2020
8GQQ	The three-dimensional structure of Cystatin A2, a cysteine protease inhibitor from Dictyostelium discoideum Descriptor: Cystatin-A2 Authors: Dinh, T.T, Dao, O, Lee, K.H. Deposit date: 2022-08-30 Release date: 2023-09-06 Method: X-RAY DIFFRACTION (1.069 Å) Cite: The three-dimensional structure of Cystatin A2, a cysteine protease inhibitor from Dictyostelium discoideum To Be Published
6CL9	2.20 A MicroED structure of proteinase K at 4.3 e- / A^2 Descriptor: Proteinase K Authors: Hattne, J, Shi, D, Glynn, C, Zee, C.-T, Gallagher-Jones, M, Martynowycz, M.W, Rodriguez, J.A, Gonen, T. Deposit date: 2018-03-02 Release date: 2018-05-16 Last modified: 2023-10-04 Method: ELECTRON CRYSTALLOGRAPHY (2.2 Å) Cite: Analysis of Global and Site-Specific Radiation Damage in Cryo-EM. Structure, 26, 2018
6LAP	Cryo-EM structure of echovirus 11 A-particle at pH 7.4 Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3 Authors: Liu, S, Gao, F.G. Deposit date: 2019-11-13 Release date: 2020-10-07 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (2.49 Å) Cite: Molecular and structural basis of Echovirus 11 infection by using the dual-receptor system of CD55 and FcRn. Chin.Sci.Bull., 2020
7NET	Crystal structure of the v-Src SH3 domain W95R-I96T mutant Descriptor: DI(HYDROXYETHYL)ETHER, SULFATE ION, TRIETHYLENE GLYCOL, ... Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.5 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
8GRZ	X-ray crystal structure of V71C human neuroglobin mutant Descriptor: Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE Authors: Lin, Y.W. Deposit date: 2022-09-03 Release date: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: X-ray crystal structure of V71C human neuroglobin mutant To Be Published
4NGK	Previously de-ionized HEW lysozyme batch crystallized in 0.2 M CoCl2 Descriptor: CHLORIDE ION, COBALT (II) ION, Lysozyme C Authors: Benas, P, Legrand, L, Ries-Kautt, M. Deposit date: 2013-11-02 Release date: 2014-05-28 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Weak protein-cationic co-ion interactions addressed by X-ray crystallography and mass spectrometry. Acta Crystallogr.,Sect.D, 70, 2014
7UGB	Crystal structure of rat ERK2 complexed with docking peptide from ISG20 Descriptor: Interferon-stimulated gene 20 kDa protein, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Torres Robles, J, Stiegler, A.L, Boggon, T.J, Turk, B.E. Deposit date: 2022-03-24 Release date: 2023-03-29 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.9 Å) Cite: To be determined To Be Published
7NER	Crystal structure of the v-Src SH3 domain Q128R mutant Descriptor: SULFATE ION, TETRAETHYLENE GLYCOL, v-Src SH3 domain Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.55 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
5WNH	X-RAY CO-STRUCTURE OF RHO-ASSOCIATED PROTEIN KINASE (ROCK1) WITH A HIGHLY SELECTIVE INHIBITOR Descriptor: (2R)-N-(3-cyanophenyl)-2-{3-[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)carbamoyl]phenyl}pyrrolidine-1-carboxamide, Rho-associated protein kinase 1 Authors: Li, X. Deposit date: 2017-07-31 Release date: 2018-08-01 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Novel mechanism of Rho kinase selectivity: beyond the ATP pocket To Be Published

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