3MH4
 
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3MH5
 | | HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | | Descriptor: | DIISOPROPYL PHOSPHONATE, Protease do | | Authors: | Krojer, T, Sawa, J, Huber, R, Clausen, T. | | Deposit date: | 2010-04-07 | | Release date: | 2010-06-30 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
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3MH7
 | | HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues | | Descriptor: | 5-mer peptide, Protease do | | Authors: | Krojer, T, Sawa, J, Huber, R, Clausen, T. | | Deposit date: | 2010-04-07 | | Release date: | 2010-06-30 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (2.961 Å) | | Cite: | HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
Nat.Struct.Mol.Biol., 17, 2010
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4L8N
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3OU0
 | | re-refined 3CS0 | | Descriptor: | Periplasmic serine endoprotease DegP, heptapeptide, pentapeptide | | Authors: | Sauer, R.T, Grant, R.A, Kim, S. | | Deposit date: | 2010-09-14 | | Release date: | 2011-01-19 | | Last modified: | 2012-02-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Covalent Linkage of Distinct Substrate Degrons Controls Assembly and Disassembly of DegP Proteolytic Cages.
Cell(Cambridge,Mass.), 145, 2011
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3SHW
 | | Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide | | Descriptor: | Gap junction gamma-1 protein, Tight junction protein ZO-1 | | Authors: | Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M. | | Deposit date: | 2011-06-17 | | Release date: | 2011-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
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3STJ
 | | Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli | | Descriptor: | Protease degQ, peptide (UNK) | | Authors: | Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T. | | Deposit date: | 2011-07-11 | | Release date: | 2011-07-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
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3SUZ
 | | Crystal structure of Rat Mint2 PPC | | Descriptor: | Amyloid beta A4 precursor protein-binding family A member 2 | | Authors: | Shen, Y, Long, J, Yan, X, Xie, X. | | Deposit date: | 2011-07-11 | | Release date: | 2012-07-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Open-closed motion of Mint2 regulates APP metabolism
J Mol Cell Biol, 5, 2013
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3TMH
 | | Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1 | | Descriptor: | A-kinase anchor protein 10, mitochondrial, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, ... | | Authors: | Sarma, G.N, Phan, R.H, Sankaran, B, Taylor, S.S. | | Deposit date: | 2011-08-31 | | Release date: | 2012-09-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Differential mode of D-AKAP2 to PKA isoforms: Insights from D-AKAP2 PKA RII PDZK1 ternary complex structure
To be Published
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3TSZ
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3TSW
 | | crystal structure of the PDZ3-SH3-GUK core module of Human ZO-1 | | Descriptor: | SULFATE ION, Tight junction protein ZO-1 | | Authors: | Nomme, J, Lavie, A. | | Deposit date: | 2011-09-13 | | Release date: | 2011-10-12 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.847 Å) | | Cite: | The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1.
J.Biol.Chem., 286, 2011
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3CS0
 | | Crystal structure of DegP24 | | Descriptor: | Periplasmic serine endoprotease DegP, pentapeptide | | Authors: | Krojer, T, Sawa, J, Schaefer, E, Saibil, H.R, Ehrmann, M, Clausen, T. | | Deposit date: | 2008-04-08 | | Release date: | 2008-05-27 | | Last modified: | 2019-11-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural basis for the regulated protease and chaperone function of DegP
Nature, 453, 2008
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4P2A
 | | Structure of mouse VPS26A bound to rat SNX27 PDZ domain | | Descriptor: | MERCURY (II) ION, Sorting nexin-27, Vacuolar protein sorting-associated protein 26A | | Authors: | Clairfeuille, T, Gallon, M, Mas, C, Ghai, R, Teasdale, R, Cullen, P, Collins, B. | | Deposit date: | 2014-03-03 | | Release date: | 2014-09-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4QL6
 | | Structure of C. trachomatis CT441 | | Descriptor: | Carboxy-terminal processing protease | | Authors: | Kohlmann, F, Hilgenfeld, R, Hansen, G. | | Deposit date: | 2014-06-10 | | Release date: | 2014-11-05 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.97 Å) | | Cite: | Structural basis of the proteolytic and chaperone activity of Chlamydia trachomatis CT441
J.Bacteriol., 197, 2015
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1Z87
 | | solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin | | Descriptor: | Alpha-1-syntrophin | | Authors: | Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M. | | Deposit date: | 2005-03-30 | | Release date: | 2006-01-24 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
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1P1D
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2KRG
 | | Solution Structure of human sodium/ hydrogen exchange regulatory factor 1(150-358) | | Descriptor: | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | | Authors: | Bhattacharya, S, Dai, Z, Li, J, Baxter, S, Callaway, D.J.E, Cowburn, D, Bu, Z. | | Deposit date: | 2009-12-17 | | Release date: | 2009-12-29 | | Last modified: | 2023-07-26 | | Method: | SOLUTION NMR | | Cite: | A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation.
J.Biol.Chem., 285, 2010
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2HGA
 | | Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A | | Descriptor: | Conserved protein MTH1368 | | Authors: | Liu, G, Lin, Y, Parish, D, Shen, Y, Sukumaran, D, Yee, A, Semesi, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2006-06-26 | | Release date: | 2006-07-25 | | Last modified: | 2022-12-21 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A
TO BE PUBLISHED
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8T1J
 | | Uncrosslinked nNOS-CaM oxygenase homodimer | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ... | | Authors: | Lee, K, Pospiech, T.H, Southworth, D. | | Deposit date: | 2023-06-02 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry.
J.Biol.Chem., 300, 2023
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8T1K
 | | DSBU crosslinked nNOS-CaM oxygenase homodimer | | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, Nitric oxide synthase 1, ... | | Authors: | Lee, K, Pospiech, T.H, Southworth, D. | | Deposit date: | 2023-06-02 | | Release date: | 2023-11-29 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.14 Å) | | Cite: | Mapping interactions of calmodulin and neuronal NO synthase by crosslinking and mass spectrometry.
J.Biol.Chem., 300, 2023
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5MV9
 | | Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain | | Descriptor: | ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ... | | Authors: | Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. | | Deposit date: | 2017-01-16 | | Release date: | 2017-07-05 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Myosin 7 and its adaptors link cadherins to actin.
Nat Commun, 8, 2017
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5MV8
 | | Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain | | Descriptor: | GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... | | Authors: | Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. | | Deposit date: | 2017-01-16 | | Release date: | 2017-07-05 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Myosin 7 and its adaptors link cadherins to actin.
Nat Commun, 8, 2017
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5N7F
 | | MAGI-1 complexed with a pRSK1 peptide | | Descriptor: | CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... | | Authors: | Gogl, G, Nyitray, L. | | Deposit date: | 2017-02-20 | | Release date: | 2017-11-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Dynamic control of RSK complexes by phosphoswitch-based regulation.
FEBS J., 285, 2018
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5N7G
 | | MAGI-1 complexed with a synthetic pRSK1 peptide | | Descriptor: | CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... | | Authors: | Gogl, G, Nyitray, L. | | Deposit date: | 2017-02-20 | | Release date: | 2017-11-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Dynamic control of RSK complexes by phosphoswitch-based regulation.
FEBS J., 285, 2018
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5N7D
 | | MAGI-1 complexed with a RSK1 peptide | | Descriptor: | CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... | | Authors: | Gogl, G, Nyitray, L. | | Deposit date: | 2017-02-20 | | Release date: | 2017-11-08 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Dynamic control of RSK complexes by phosphoswitch-based regulation.
FEBS J., 285, 2018
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