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6Q0H	Inferred intermediate I-7 (I-7-0) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-01 Release date: 2019-12-18 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q18	Human antibody H1244 in complex with the influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, H1244 Fab heavy chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-03 Release date: 2019-12-18 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q1A	Inferred intermediate mutant (I-6V) of the human antibody lineage 652 Descriptor: Fab heavy chain, Fab lambda chain, GLYCEROL Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-03 Release date: 2019-12-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.001 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q0L	Inferred intermediate I-7 (I-7-1) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-01 Release date: 2019-12-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6W51	Structure of the antibody fragment H2 in complex with HLA-A*02:01/p53R175H Descriptor: Beta-2-microglobulin, Cellular tumor antigen p53 peptide, Immunoglobulin heavy chain H2, ... Authors: Wright, K.M, Gabelli, S.B. Deposit date: 2020-03-12 Release date: 2021-03-17 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.53 Å) Cite: Targeting a neoantigen derived from a common TP53 mutation. Science, 371, 2021
6Q0I	Inferred intermediate I-7 (I-7-6) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-01 Release date: 2019-12-18 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.702 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q1K	Inferred intermediate I-7 of the human antibody lineage 652 Descriptor: Fab heavy chain, Fab lambda light chain, GLYCEROL Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-05 Release date: 2019-12-18 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q0E	Inferred precursor (UCA) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1) Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Fab heavy chain, Fab lambda light chain, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-01 Release date: 2019-12-18 Last modified: 2020-01-01 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
6Q0O	human antibody H2227 lineage 652 in complex with influenza hemagglutinin head domain of A/Solomon Islands/3/2006(H1N1) Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... Authors: McCarthy, K.R, Harrison, S.C. Deposit date: 2019-08-02 Release date: 2019-12-18 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3 Å) Cite: Affinity maturation in a human humoral response to influenza hemagglutinin. Proc.Natl.Acad.Sci.USA, 2019
7EKB	Crystal structure of 4E10 modified with pyrene acetamide Descriptor: ACETATE ION, Fab region of the heavy chain of broadly neutralizing antibody anti-HIV-1 4E10, Fab region of the light chain of the broadly neutralizing anti-HIV-1 antibody 4E10, ... Authors: Caaveiro, J.M.M, Rujas, E, Nieva, J.L. Deposit date: 2021-04-05 Release date: 2021-08-11 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile. Iscience, 24, 2021
5WTG	Crystal structure of the Fab fragment of anti-HAV antibody R10 Descriptor: FAB Heavy chain, FAB Light chain Authors: Wang, X, Zhu, L, Dang, M, Hu, Z, Gao, Q, Yuan, S, Sun, Y, Zhang, B, Ren, J, Walter, T.S, Wang, J, Fry, E.E, Stuart, D.I, Rao, Z. Deposit date: 2016-12-11 Release date: 2017-01-25 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.907 Å) Cite: Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7VMZ	Crystal structure of a human Coronavirus 229E antibody C04 Fab Descriptor: C04 Fab Heavy Chain, C04 Fab Light Chain Authors: Xiang, J.C, Yang, B. Deposit date: 2021-10-10 Release date: 2022-10-12 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.85 Å) Cite: Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein. Commun Biol, 5, 2022
6Y1L	Crystal structure of the paraoxon-modified A.17 antibody FAB fragment - L47R mutant Descriptor: DIETHYL PHOSPHONATE, FAB A.17 L47R mutant HEAVY CHAIN, FAB A.17 L47R mutant Light CHAIN, ... Authors: Chatziefthimiou, S, Mokrushina, Y, Smirnov, I, Gabibov, A, Wilmanns, M. Deposit date: 2020-02-12 Release date: 2020-09-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proc.Natl.Acad.Sci.USA, 117, 2020
6Y1N	Crystal structure of the phosphonate-modified A.5 antibody FAB fragment Descriptor: 8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-YL PHENYLPHOSPHONATE, FAB A.5 Heavy chain, FAB A.5 Light Chain Authors: Chatziefthimiou, S, Mokrushina, Y, Smirnov, I, Gabibov, A, Wilmanns, M. Deposit date: 2020-02-12 Release date: 2020-09-23 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proc.Natl.Acad.Sci.USA, 117, 2020
6Y1K	Crystal structure of the unmodified A.17 antibody FAB fragment - L47R mutant Descriptor: FAB A.17 L47R mutant Heavy Chain, FAB A.17 L47R mutant Light Chain Authors: Chatziefthimiou, S, Stepanova, A, Mokrushina, Y, Smirnov, I, Gabibov, A, Wilmanns, M. Deposit date: 2020-02-12 Release date: 2020-09-16 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proc.Natl.Acad.Sci.USA, 117, 2020
7UAP	Structure of the SARS-CoV-2 S 6P trimer in complex with the neutralizing antibody Fab fragment, C1520 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C1520 Fab Heavy Chain, ... Authors: Barnes, C.O. Deposit date: 2022-03-13 Release date: 2022-04-27 Last modified: 2022-06-22 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins. Immunity, 55, 2022
7UAR	Structure of the SARS-CoV-2 S 6P trimer in complex with the neutralizing antibody Fab fragment, C1717 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C1717 Fab Heavy Chain, ... Authors: Barnes, C.O. Deposit date: 2022-03-13 Release date: 2022-04-27 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins. Immunity, 55, 2022
6Y1M	Crystal structure of the paraoxon-modified A.17 antibody FAB fragment - L47K mutant Descriptor: DIETHYL PHOSPHONATE, FAB A.17 L47K mutant HEAVY CHAIN, FAB A.17 L47K mutant Light CHAIN Authors: Chatziefthimiou, S, Mokrushina, Y, Smirnov, I, Gabibov, A, Wilmanns, M. Deposit date: 2020-02-12 Release date: 2020-09-16 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers. Proc.Natl.Acad.Sci.USA, 117, 2020
7BM5	Crystal structure of Fab1, the Fab fragment of the anti-BamA monoclonal antibody MAB1 Descriptor: Fab1 heavy chain, Fab1 light chain Authors: White, P, Storek, K.M, Rutherford, S.T, Radford, S.E. Deposit date: 2021-01-19 Release date: 2021-06-02 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.95 Å) Cite: The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding. Nat Commun, 12, 2021
7U2E	Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody ADI-55688 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-55688 heavy chain, ADI-55688 light chain, ... Authors: Yuan, M, Zhu, X, Wilson, I.A. Deposit date: 2022-02-23 Release date: 2022-05-04 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (2.85 Å) Cite: A broad and potent neutralization epitope in SARS-related coronaviruses. Proc.Natl.Acad.Sci.USA, 119, 2022
8T58	Structure of VHH-Fab complex with engineered FNQIKG elbow region Descriptor: CHLORIDE ION, Fab heavy chain, Fab light chain, ... Authors: Filippova, E.V, Kossiakoff, A.A. Deposit date: 2023-06-12 Release date: 2023-11-29 Last modified: 2024-01-03 Method: X-RAY DIFFRACTION (2.23 Å) Cite: Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes. Protein Sci., 33, 2024
7JZK	Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_0401300) V2 domain Descriptor: LAIR1 ecotodomain from MGD21 antibody, Rifin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Xu, K, Kwong, P.D. Deposit date: 2020-09-02 Release date: 2021-05-26 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.457 Å) Cite: Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021
7JZ4	Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MGD21 heavy chain, MGD21 light chain, ... Authors: Xu, K, Kwong, P.D. Deposit date: 2020-09-01 Release date: 2021-05-26 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.747 Å) Cite: Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021
7JZI	Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain Descriptor: LAIR1 ectodomain from antibody MGD21, PLATINUM (II) ION, Rifin Authors: Xu, K, Kwong, P.D. Deposit date: 2020-09-02 Release date: 2021-05-26 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.707 Å) Cite: Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021
7JZ1	Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34 Descriptor: MGC34 heavy chain, MGC34 light chain Authors: Xu, K, Kwong, P.D. Deposit date: 2020-09-01 Release date: 2021-05-26 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.37 Å) Cite: Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021

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