8P03
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![BU of 8p03 by Molmil](/molmil-images/mine/8p03) | 48S late-stage initiation complex with m6A mRNA | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | Authors: | Guca, E, Lima, L.H.F, Boissier, F, Hashem, Y. | Deposit date: | 2023-05-09 | Release date: | 2024-03-20 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | N 6 -methyladenosine in 5' UTR does not promote translation initiation. Mol.Cell, 84, 2024
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8PEE
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![BU of 8pee by Molmil](/molmil-images/mine/8pee) | ABCB1 L335C mutant (mABCB1) in the inward facing state bound to AAC | Descriptor: | (4S,11S,18S)-4-[[(2,4-dinitrophenyl)disulfanyl]methyl]-11,18-dimethyl-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, ATP-dependent translocase ABCB1, ... | Authors: | Parey, K, Januliene, D, Gewering, T, Moeller, A. | Deposit date: | 2023-06-13 | Release date: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Tracing the substrate translocation mechanism in P-glycoprotein. Elife, 12, 2024
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7PRO
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7PR1
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![BU of 7pr1 by Molmil](/molmil-images/mine/7pr1) | |
7PRU
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8PMJ
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![BU of 8pmj by Molmil](/molmil-images/mine/8pmj) | Vanadate-trapped BSEP in nanodiscs | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Bile salt export pump, ... | Authors: | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | Deposit date: | 2023-06-28 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.81 Å) | Cite: | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP. Nat Commun, 14, 2023
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8PMD
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![BU of 8pmd by Molmil](/molmil-images/mine/8pmd) | Nucleotide-bound BSEP in nanodiscs | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Bile salt export pump, MAGNESIUM ION | Authors: | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | Deposit date: | 2023-06-28 | Release date: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP. Nat Commun, 14, 2023
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7QKS
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7QKR
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![BU of 7qkr by Molmil](/molmil-images/mine/7qkr) | Cryo-EM structure of ABC transporter STE6-2p from Pichia pastoris with Verapamil at 3.2 A resolution | Descriptor: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, Dexverapamil, MAGNESIUM ION, ... | Authors: | Schleker, E.S.M, Reinhart, C. | Deposit date: | 2021-12-18 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural and functional investigation of ABC transporter STE6-2p from Pichia pastoris reveals unexpected interaction with sterol molecules. Proc.Natl.Acad.Sci.USA, 119, 2022
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7QBA
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![BU of 7qba by Molmil](/molmil-images/mine/7qba) | CryoEM structure of the ABC transporter NosDFY complexed with nitrous oxide reductase NosZ | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Zipfel, S, Mueller, C, Topitsch, A, Lutz, M, Zhang, L, Einsle, O. | Deposit date: | 2021-11-18 | Release date: | 2022-08-03 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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8QOE
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![BU of 8qoe by Molmil](/molmil-images/mine/8qoe) | Inward-facing conformation of the ABC transporter BmrA | Descriptor: | Multidrug resistance ABC transporter ATP-binding/permease protein BmrA | Authors: | Di Cesare, M, Kaplan, E, Valimehr, S, Hanssen, E, Orelle, C, Jault, J.M. | Deposit date: | 2023-09-28 | Release date: | 2023-12-20 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | The transport activity of the multidrug ABC transporter BmrA does not require a wide separation of the nucleotide-binding domains. J.Biol.Chem., 300, 2023
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8P8A
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![BU of 8p8a by Molmil](/molmil-images/mine/8p8a) | Structure of 5D3-Fab and nanobody(Nb17)-bound ABCG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5D3(Fab) heavy chain variable domain, 5D3(Fab) light chain variable domain, ... | Authors: | Irobalieva, R.N, Manolaridis, I, Jackson, S.M, Ni, D, Pardon, E, Stahlberg, H, Steyaert, J, Locher, K.P. | Deposit date: | 2023-05-31 | Release date: | 2023-08-30 | Last modified: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies. J.Mol.Biol., 435, 2023
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8SCB
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![BU of 8scb by Molmil](/molmil-images/mine/8scb) | Terminating ribosome with SRI-41315 | Descriptor: | (2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione, 18S_rRNA, 28S_rRNA, ... | Authors: | Yip, M.C.J, Coelho, J.P.L, Oltion, K, Tauton, J, Shao, S. | Deposit date: | 2023-04-05 | Release date: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structure and consequences of eRF1 glued to the ribosomal decoding center To Be Published
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8RQ4
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8RQ3
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7CGE
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![BU of 7cge by Molmil](/molmil-images/mine/7cge) | The overall structure of nucleotide free MlaFEDB complex | Descriptor: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | Authors: | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | Deposit date: | 2020-07-01 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
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7CGN
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![BU of 7cgn by Molmil](/molmil-images/mine/7cgn) | The overall structure of the MlaFEDB complex in ATP-bound EQtall conformation (Mutation of E170Q on MlaF) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | Authors: | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | Deposit date: | 2020-07-01 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
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7CAF
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![BU of 7caf by Molmil](/molmil-images/mine/7caf) | Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CAG
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![BU of 7cag by Molmil](/molmil-images/mine/7cag) | Mycobacterium smegmatis LpqY-SugABC complex in the catalytic intermediate state | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.78 Å) | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CAD
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![BU of 7cad by Molmil](/molmil-images/mine/7cad) | Mycobacterium smegmatis SugABC complex | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CH0
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![BU of 7ch0 by Molmil](/molmil-images/mine/7ch0) | The overall structure of the MlaFEDB complex in ATP-bound EQclose conformation (Mutation of E170Q on MlaF) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, ... | Authors: | Chi, X.M, Fan, Q.X, Zhang, Y.Y, Liang, K, Zhou, Q, Li, Y.Y. | Deposit date: | 2020-07-03 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural mechanism of phospholipids translocation by MlaFEDB complex. Cell Res., 30, 2020
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7CAE
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![BU of 7cae by Molmil](/molmil-images/mine/7cae) | Mycobacterium smegmatis LpqY-SugABC complex in the resting state | Descriptor: | ABC sugar transporter, permease component, ABC transporter, ... | Authors: | Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z. | Deposit date: | 2020-06-08 | Release date: | 2020-12-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC. Sci Adv, 6, 2020
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7CHA
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![BU of 7cha by Molmil](/molmil-images/mine/7cha) | Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-05-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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7SHN
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![BU of 7shn by Molmil](/molmil-images/mine/7shn) | Cryo-EM structure of oleoyl-CoA-bound human peroxisomal fatty acid transporter ABCD1 | Descriptor: | ATP-binding cassette sub-family D member 1, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name) | Authors: | Wang, R, Li, X. | Deposit date: | 2021-10-09 | Release date: | 2021-11-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of acyl-CoA transport across the peroxisomal membrane by human ABCD1. Cell Res., 32, 2022
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7SHM
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