8PMD

Nucleotide-bound BSEP in nanodiscs

Summary for 8PMD

Entry DOI	10.2210/pdb8pmd/pdb
EMDB information	17759
Descriptor	Bile salt export pump, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	transport, nucleotide, nanodiscs, protein transport
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	147619.38
Authors	Liu, H.,Irobalieva, R.N.,Kowal, J.,Ni, D.,Nosol, K.,Bang-Sorensen, R.,Lancien, L.,Stahlberg, H.,Stieger, B.,Locher, K.P. (deposition date: 2023-06-28, release date: 2023-11-22)
Primary citation	Liu, H.,Irobalieva, R.N.,Kowal, J.,Ni, D.,Nosol, K.,Bang-Sorensen, R.,Lancien, L.,Stahlberg, H.,Stieger, B.,Locher, K.P. Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP. Nat Commun, 14:7296-7296, 2023 Cited by PubMed: 37949847 DOI: 10.1038/s41467-023-43109-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.95 Å)

Structure validation