1A7N
 
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1A7Q
 | | FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) HIGH AFFINITY EXPRESSED VARIANT CONTAINING SER26L->GLY, ILE29L->THR, GLU81L->ASP, THR97L->SER, PRO240H->LEU, ASP258H->ALA, LYS281H->GLU, ASN283H->ASP AND LEU312H->VAL | | Descriptor: | IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN) | | Authors: | Marks, C, Henrick, K, Winter, G. | | Deposit date: | 1998-03-16 | | Release date: | 1998-04-29 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-Ray Structures of D1.3 Fv Mutants
To be Published
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1A7O
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5KJR
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5DQJ
 | | Structure of unliganded S55-5 Fab | | Descriptor: | S55-5 Fab (IgG1 kappa) light chain, S55-5 Fab (IgG1) heavy chain | | Authors: | Haji-Ghassemi, O, Evans, S.V. | | Deposit date: | 2015-09-14 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Lipid A-antibody structures reveal a widely-utilized pocket specific for negatively charged groups derived from unrelated V-genes
J.Biol.Chem., 2015
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1A7R
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5DQ9
 | | Structure of S55-3 Fab in complex with Lipid A | | Descriptor: | 2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, MAb 44B1 light chain, ... | | Authors: | Haji-Ghassemi, O, Evans, S.V. | | Deposit date: | 2015-09-14 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Lipid A-antibody structures reveal a widely-utilized pocket specific for negatively charged groups derived from from unrelated V-genes
J.Biol.Chem., 2015
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5DQD
 | | Structure of S55-5 Fab in complex with lipid A carbohydrate backbone | | Descriptor: | 2-acetamido-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, S55-5 Fab (IgG1 kappa) light chain, ... | | Authors: | Haji-Ghassemi, O, Evans, S.V. | | Deposit date: | 2015-09-14 | | Release date: | 2016-03-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Lipid A-antibody structures reveal a widely-utilized pocket specific for negatively charged groups derived from unrelated V-genes
J.Biol.Chem., 2015
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1A7P
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3IDY
 | | Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab b13 heavy chain, Fab b13 light chain, ... | | Authors: | Chen, L, Kwon, Y.D, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z.Y, Zhang, M.Y, Arthos, J, Burton, D.R, Dimitrov, D.S, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D. | | Deposit date: | 2009-07-22 | | Release date: | 2009-11-17 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120.
Science, 326, 2009
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1FOR
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3QSK
 | | 5 Histidine Variant of the anti-RNase A VHH in Complex with RNAse A | | Descriptor: | Engineered 5 Histidine anti-RNase A Camelid VHH Antibody Domain Variant, Ribonuclease pancreatic | | Authors: | Murtaugh, M.L, Fanning, S.W, Sharma, T.M, Terry, A.M, Horn, J.R. | | Deposit date: | 2011-02-21 | | Release date: | 2011-08-10 | | Last modified: | 2011-11-30 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A combinatorial histidine scanning library approach to engineer highly pH-dependent protein switches.
Protein Sci., 20, 2011
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8VK2
 | | X-ray crystal structure of human IgE 4C8 Fab | | Descriptor: | IgE 4C8 heavy chain, IgE 4C8 light chain | | Authors: | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | | Deposit date: | 2024-01-08 | | Release date: | 2024-06-19 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (2.508 Å) | | Cite: | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2.
J.Allergy Clin.Immunol., 154, 2024
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2IMM
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1F6L
 | | VARIABLE LIGHT CHAIN DIMER OF ANTI-FERRITIN ANTIBODY | | Descriptor: | ANTI-FERRITIN IMMUNOGLOBULIN LIGHT CHAIN | | Authors: | Nymalm, Y, Kravchuk, Z, Salminen, T, Chumanevich, A.A, Dubnovitsky, A.P, Kankare, J, Pentikainen, O, Lehtonen, J, Arosio, P, Martsev, S, Johnson, M.S. | | Deposit date: | 2000-06-22 | | Release date: | 2002-10-23 | | Last modified: | 2018-04-04 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Antiferritin VL homodimer binds human spleen ferritin with high specificity
J.STRUCT.BIOL., 138, 2002
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4H0I
 | | Crystal Structure of Scfv-2D10 in Complex with Methyl Alpha-D-Mannopyranoside | | Descriptor: | 2D10 scFv, MAGNESIUM ION, methyl alpha-D-mannopyranoside | | Authors: | Tapryal, S, Gaur, V, Kaur, K.J, Salunke, D.M. | | Deposit date: | 2012-09-08 | | Release date: | 2013-06-19 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural evaluation of a mimicry-recognizing paratope: plasticity in antigen-antibody interactions manifests in molecular mimicry.
J.Immunol., 191, 2013
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7JTR
 | | Complex of maltose-binding protein (MBP) with single-chain Fv (scFv) | | Descriptor: | CHLORIDE ION, Maltose/maltodextrin-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | Authors: | Loll, P.J. | | Deposit date: | 2020-08-18 | | Release date: | 2021-05-05 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A useful epitope tag derived from maltose binding protein.
Protein Sci., 30, 2021
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6ORN
 | | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074 | | Descriptor: | 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | | Deposit date: | 2019-04-30 | | Release date: | 2019-06-12 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (4.05 Å) | | Cite: | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
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4HGW
 | | Crystal structure of S25-2 in complex with a 5,6-dehydro-Kdo disaccharide | | Descriptor: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3,5-dideoxy-alpha-D-threo-oct-5-en-2-ulopyranosidonic acid, Antibody Fab fragment, heavy chain, ... | | Authors: | Brooks, C.L, Evans, S.V. | | Deposit date: | 2012-10-08 | | Release date: | 2013-01-09 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide.
Acta Crystallogr.,Sect.F, 69, 2013
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8VK1
 | | X-ray crystal structure of human IgE 4C8 Fab complex with Der p 2.0103 | | Descriptor: | Der p 2 variant 3, IgE 4C8 heavy chain, IgE 4C8 light chain | | Authors: | Khatri, K, Ball, A, Smith, S.A, Champan, M.D, Pomes, A, Chruszcz, M. | | Deposit date: | 2024-01-08 | | Release date: | 2024-06-19 | | Last modified: | 2024-08-21 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2.
J.Allergy Clin.Immunol., 154, 2024
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1K4C
 | | Potassium Channel KcsA-Fab complex in high concentration of K+ | | Descriptor: | DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... | | Authors: | Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R. | | Deposit date: | 2001-10-07 | | Release date: | 2001-11-14 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution.
Nature, 414, 2001
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1K4D
 | | Potassium Channel KcsA-Fab complex in low concentration of K+ | | Descriptor: | DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... | | Authors: | Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R. | | Deposit date: | 2001-10-07 | | Release date: | 2001-11-14 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution.
Nature, 414, 2001
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4KZE
 | | Crystal structure of an RNA aptamer in complex with Fab | | Descriptor: | BL3-6 Fab antibody, heavy chain, light chain, ... | | Authors: | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | | Deposit date: | 2013-05-29 | | Release date: | 2014-06-18 | | Last modified: | 2014-07-30 | | Method: | X-RAY DIFFRACTION (2.404 Å) | | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Nat.Chem.Biol., 10, 2014
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6ZEC
 | | Crystal Structure of the Fab Fragment of a Glycosylated Lymphoma Antibody | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment heavy chain, Fab fragment light chain, ... | | Authors: | Allen, J.D, Watanabe, Y, Crispin, M, Bowden, T.A. | | Deposit date: | 2020-06-16 | | Release date: | 2021-06-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behavior.
Blood, 138, 2021
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7KCR
 | | Cryo-EM structure of Zika virus in complex with E protein cross-linking human monoclonal antibody ADI30056 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADI30056 Fab heavy chain variable region, ADI30056 Fab light chain variable region, ... | | Authors: | Sevvana, M, Rogers, T.F, Miller, A.S, Long, F, Klose, T, Beutler, N, Lai, Y.C, Parren, M, Walker, L.M, Buda, G, Burton, D.R, Rossmann, M.G, Kuhn, R.J. | | Deposit date: | 2020-10-07 | | Release date: | 2020-12-16 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections.
Viruses, 12, 2020
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