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8QMH
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Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77
Descriptor: 3-(7-azanyl-1,8-naphthyridin-2-yl)-2-[(7-azanyl-1,8-naphthyridin-2-yl)methyl]-~{N}-(3-azanylpropyl)propanamide, CHLORIDE ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3')
Authors:Kiliszek, A, Ryczek, M, Blaszczyk, L.
Deposit date:2023-09-22
Release date:2024-05-01
Last modified:2024-07-03
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand.
Nucleic Acids Res., 52, 2024
5T3K
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BU of 5t3k by Molmil
Fluorescence detection of RNA-ligand binding and crystal structure determination of ribosomal decoding site RNA using a heavy atom containing fluorescent ribonucleoside
Descriptor: MAGNESIUM ION, RNA (5'-R(*CP*AP*GP*CP*GP*(75B)P*CP*AP*CP*AP*CP*CP*AP*CP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*UP*GP*G)-3')
Authors:Hermann, T, Boerneke, M.A.
Deposit date:2016-08-25
Release date:2017-07-05
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.142 Å)
Cite:Structure of the Ribosomal RNA Decoding Site Containing a Selenium-Modified Responsive Fluorescent Ribonucleoside Probe.
Angew. Chem. Int. Ed. Engl., 56, 2017
1EC4
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BU of 1ec4 by Molmil
SOLUTION STRUCTURE OF A HEXITOL NUCLEIC ACID DUPLEX WITH FOUR CONSECUTIVE T:T BASE PAIRS
Descriptor: HEXITOL DODECANUCLEOTIDE
Authors:Lescrinier, E, Esnouf, R.M, Schraml, J, Busson, R, Herdewijn, P.
Deposit date:2000-01-25
Release date:2003-04-22
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a HNA-RNA hybrid
Chem.Biol., 7, 2000
1TFY
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BU of 1tfy by Molmil
How CCA is added to the 3' end of immature tRNA without the use of an oligonucleotide template
Descriptor: 5'-R(*CP*GP*CP*GP*GP*AP*UP*C)-3', 5'-R(*CP*GP*GP*AP*UP*CP*CP*GP*CP*AP*C)-3', 5'-R(*GP*CP*GP*GP*AP*UP*AP*UP*CP*CP*GP*CP*AP*C)-3', ...
Authors:Xiong, Y, Steitz, T.A.
Deposit date:2004-05-27
Release date:2004-08-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Mechanism of transfer RNA maturation by CCA-adding enzyme without using an oligonucleotide template.
Nature, 430, 2004
3LOA
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BU of 3loa by Molmil
Crystal Structure Analysis of the RNA construct with two adjacent ligand binding sites of helix h44 in 16S ribosomal RNA
Descriptor: 5'-R(*CP*CP*GP*CP*GP*CP*CP*CP*GP*(5BU)P*CP*AP*CP*AP*CP*CP*AP*CP*CP*CP*G)-3', 5'-R(*GP*GP*GP*(5BU)P*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*UP*AP*AP*CP*GP*CP*GP*GP*C)-3', MAGNESIUM ION, ...
Authors:Dibrov, S.
Deposit date:2010-02-03
Release date:2010-08-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:A model for the study of ligand binding to the ribosomal RNA helix h44.
Nucleic Acids Res., 38, 2010
1N93
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BU of 1n93 by Molmil
Crystal Structure of the Borna Disease Virus Nucleoprotein
Descriptor: p40 nucleoprotein
Authors:Rudolph, M.G, Kraus, I, Dickmanns, A, Garten, W, Ficner, R.
Deposit date:2002-11-22
Release date:2003-10-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of the Borna Disease Virus nucleoprotein
Structure, 11, 2003
6WTR
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BU of 6wtr by Molmil
Structure of Human pir-miRNA-300 Apical Loop Fused to the YdaO Riboswitch Scaffold
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, POTASSIUM ION, ...
Authors:Shoffner, G.M, Peng, Z, Guo, F.
Deposit date:2020-05-03
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.082 Å)
Cite:Structures of microRNA-precursor apical junctions and loops revealed by scaffold-directed crystallography: importance of non-canonical base pairs in processing
To Be Published
1X1L
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BU of 1x1l by Molmil
Interaction of ERA,a GTPase protein, with the 3'minor domain of the 16S rRNA within the THERMUS THERMOPHILUS 30S subunit.
Descriptor: GTP-binding protein era, RNA (130-MER)
Authors:Sharma, M.R, Barat, C, Agrawal, R.K.
Deposit date:2005-04-06
Release date:2005-05-17
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (13.5 Å)
Cite:Interaction of Era with the 30S Ribosomal Subunit Implications for 30S Subunit Assembly
Mol.Cell, 18, 2005
5NKM
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BU of 5nkm by Molmil
SMG8-SMG9 complex
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
Authors:Li, L, Basquin, J, Conti, E.
Deposit date:2017-03-31
Release date:2017-04-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.493 Å)
Cite:Structure of a SMG8-SMG9 complex identifies a G-domain heterodimer in the NMD effector proteins.
RNA, 23, 2017
5NG6
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BU of 5ng6 by Molmil
Crystal structure of FnCas12a bound to a crRNA
Descriptor: CRISPR-associated endonuclease Cpf1, MAGNESIUM ION, crRNA
Authors:Swarts, D.C, van der Oost, J, Jinek, M.
Deposit date:2017-03-16
Release date:2017-06-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.342 Å)
Cite:Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a.
Mol. Cell, 66, 2017
1JBS
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BU of 1jbs by Molmil
Crystal structure of ribotoxin restrictocin and a 29-mer SRD RNA analog
Descriptor: 29-mer sarcin/ricin domain RNA analog, POTASSIUM ION, restrictocin
Authors:Yang, X, Gerczei, T, Glover, L, Correll, C.C.
Deposit date:2001-06-06
Release date:2001-10-26
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystal structures of restrictocin-inhibitor complexes with implications for RNA recognition and base flipping.
Nat.Struct.Biol., 8, 2001
3AX1
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BU of 3ax1 by Molmil
Molecular insights into miRNA processing by Arabidopsis Serrate
Descriptor: Serrate RNA effector molecule, ZINC ION
Authors:Yuan, Y.A, Machida, S, Chen, H.Y.
Deposit date:2011-03-28
Release date:2011-07-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Molecular insights into miRNA processing by Arabidopsis thaliana SERRATE
Nucleic Acids Res., 39, 2011
4GV3
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BU of 4gv3 by Molmil
Structures of Lassa and Tacaribe viral nucleoproteins with or without 5 triphosphate dsRNA substrate reveal a unique 3 -5 exoribonuclease mechanism to suppress type I interferon production
Descriptor: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
Authors:Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4JZV
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BU of 4jzv by Molmil
Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - second guanosine residue in guanosine binding pocket
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, RNA (5'-R(*(GCP)P*G)-3'), ...
Authors:Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C.
Deposit date:2013-04-03
Release date:2013-05-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
1IQT
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BU of 1iqt by Molmil
Solution structure of the C-terminal RNA-binding domain of heterogeneous nuclear ribonucleoprotein D0 (AUF1)
Descriptor: heterogeneous nuclear ribonucleoprotein D0
Authors:Katahira, M, Miyanoiri, Y, Enokizono, Y, Matsuda, G, Nagata, T, Ishikawa, F, Uesugi, S.
Deposit date:2001-08-01
Release date:2002-08-07
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structure of the C-terminal RNA-binding domain of hnRNP D0 (AUF1), its interactions with RNA and DNA, and change in backbone dynamics upon complex formation with DNA.
J.Mol.Biol., 311, 2001
4JZU
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BU of 4jzu by Molmil
Crystal structure of the Bacillus subtilis pyrophosphohydrolase BsRppH bound to a non-hydrolysable triphosphorylated dinucleotide RNA (pcp-pGpG) - first guanosine residue in guanosine binding pocket
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, RNA (5'-R(*(GCP)P*G)-3'), RNA PYROPHOSPHOHYDROLASE
Authors:Piton, J, Larue, V, Thillier, Y, Dorleans, A, Pellegrini, O, Li de la Sierra-Gallay, I, Vasseur, J.J, Debart, F, Tisne, C, Condon, C.
Deposit date:2013-04-03
Release date:2013-05-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GV6
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BU of 4gv6 by Molmil
Structures of Lassa and Tacaribe viral nucleoproteins with or without 5 triphosphate dsRNA substrate reveal a unique 3 -5 exoribonuclease mechanism to suppress type I interferon production
Descriptor: MANGANESE (II) ION, Nucleoprotein, RNA (5'-R(*(GTP)P*GP*GP*C)-3'), ...
Authors:Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
6D2U
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BU of 6d2u by Molmil
Solution structure of a ultra-high affinity macrocycle bound to HIV-1 TAR RNA
Descriptor: DAB-VAL-ARG-THR-ARG-LYS-GLY-ARG-ARG-ILE-NOR-ILE-DPR-PRO, RNA (29-MER)
Authors:Shortridge, M.D, Varani, G.
Deposit date:2018-04-13
Release date:2018-12-12
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb.
Nucleic Acids Res., 47, 2019
1PP1
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BU of 1pp1 by Molmil
Crystal structure of the Borna Disease Virus Nucleoprotein
Descriptor: p40 nucleoprotein
Authors:Rudolph, M.G, Kraus, I, Dickmanns, A, Garten, W, Ficner, R.
Deposit date:2003-06-16
Release date:2003-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the Borna Disease Virus nucleoprotein
Structure, 11, 2003
4TZ0
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BU of 4tz0 by Molmil
DEAD-box helicase Mss116 bound to ssRNA and GDP-BeF
Descriptor: ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Mallam, A.L, Sidote, D.J, Lambowitz, A.M.
Deposit date:2014-07-09
Release date:2014-12-31
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Elife, 3, 2014
1MFQ
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BU of 1mfq by Molmil
Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle
Descriptor: 7S RNA of human SRP, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Kuglstatter, A, Oubridge, C, Nagai, K.
Deposit date:2002-08-13
Release date:2002-09-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Induced structural changes of 7SL RNA during the assembly of human signal recognition particle
Nat.Struct.Biol., 9, 2002
4G9Z
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BU of 4g9z by Molmil
Lassa nucleoprotein with dsRNA reveals novel mechanism for immune suppression
Descriptor: Nucleoprotein, RNA (5'-R(P*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*C)-3'), ...
Authors:Jiang, X, Huang, Q, Wang, W, Dong, H, Ly, H, Liang, Y, Dong, C, Scottish Structural Proteomics Facility (SSPF)
Deposit date:2012-07-24
Release date:2013-04-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4ZT9
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BU of 4zt9 by Molmil
Nuclease-inactive Streptococcus pyogenes Cas9 (D10A/H840A, dCas9) in complex with single-guide RNA at 3.1 Angstrom resolution
Descriptor: CRISPR-associated endonuclease Cas9, single-guide RNA
Authors:Jiang, F, Doudna, J.A.
Deposit date:2015-05-14
Release date:2015-07-08
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:A Cas9-guide RNA complex preorganized for target DNA recognition.
Science, 348, 2015
3JB6
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BU of 3jb6 by Molmil
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ...
Authors:Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H.
Deposit date:2015-08-02
Release date:2015-10-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
8SH5
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BU of 8sh5 by Molmil
Crystal structure of 3'cap-independent translation enhancers (CITE) from Pea enation mosaic virus RNA 2 (PEMV2) with Fab BL3-6K170A
Descriptor: Fab BL3-6K170A heavy chain, Fab BL3-6K170A light chain, RNA (88-MER)
Authors:Lewicka, A, Roman, C, Rice, P.A, Piccirilli, J.A.
Deposit date:2023-04-13
Release date:2023-08-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of a cap-independent translation enhancer RNA.
Nucleic Acids Res., 51, 2023

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