5L1T
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2FF2
| Crystal structure of Trypanosoma vivax nucleoside hydrolase co-crystallized with ImmucillinH | Descriptor: | 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, CALCIUM ION, IAG-nucleoside hydrolase, ... | Authors: | Versees, W, Barlow, J, Steyaert, J. | Deposit date: | 2005-12-18 | Release date: | 2006-05-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis. J.Mol.Biol., 359, 2006
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2LB3
| Structure of the WW domain of PIN1 in complex with a human phosphorylated Smad3 derived peptide | Descriptor: | Mothers against decapentaplegic homolog 2, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Macias, M.J, Aragon, E, Goerner, N, Zaromytidou, A, Xi, Q, Escobedo, A, Massague, J. | Deposit date: | 2011-03-22 | Release date: | 2011-07-06 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | A Smad action turnover switch operated by WW domain readers of a phosphoserine code. Genes Dev., 25, 2011
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5IWW
| Crystal structure of RNA editing factor of designer PLS-type PPR/9R protein in complex with MORF9/RIP9 | Descriptor: | Multiple organellar RNA editing factor 9, chloroplastic, PLS9-PPR | Authors: | Yan, J, Zhang, Q, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-03-23 | Release date: | 2017-03-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | MORF9 increases the RNA-binding activity of PLS-type pentatricopeptide repeat protein in plastid RNA editing Nat Plants, 3, 2017
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2FWV
| Crystal Structure of Rv0813 | Descriptor: | 1,4-DIETHYLENE DIOXIDE, GLYCEROL, hypothetical protein MtubF_01000852 | Authors: | Shepard, W, Haouz, A, Grana, M, Buschiazzo, A, Betton, J.M, Cole, S.T, Alzari, P.M, Structural Proteomics in Europe (SPINE) | Deposit date: | 2006-02-03 | Release date: | 2006-08-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of Rv0813c from Mycobacterium tuberculosis Reveals a New Family of Fatty Acid-Binding Protein-Like Proteins in Bacteria J.Bacteriol., 189, 2007
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1OSH
| A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR | Descriptor: | Bile acid receptor, METHYL 3-{3-[(CYCLOHEXYLCARBONYL){[4'-(DIMETHYLAMINO)BIPHENYL-4-YL]METHYL}AMINO]PHENYL}ACRYLATE | Authors: | Downes, M, Verdecia, M.A, Roecker, A.J, Hughes, R, Hogenesch, J.B, Kast-Woelbern, H.R, Bowman, M.E, Ferrer, J.-L, Anisfeld, A.M, Edwards, P.A, Rosenfeld, J.M, Alvarez, J.G.A, Noel, J.P, Nicolaou, K.C, Evans, R.M. | Deposit date: | 2003-03-19 | Release date: | 2003-09-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR Mol.Cell, 11, 2003
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2MDJ
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2LXM
| Lip5-chmp5 | Descriptor: | Charged multivesicular body protein 5, Vacuolar protein sorting-associated protein VTA1 homolog | Authors: | Skalicky, J.J, Sundquist, W.I. | Deposit date: | 2012-08-29 | Release date: | 2012-11-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport. J.Biol.Chem., 287, 2012
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2MDC
| Solution structure of the WW domain of HYPB | Descriptor: | Histone-lysine N-methyltransferase SETD2 | Authors: | Gao, Y.G. | Deposit date: | 2013-09-10 | Release date: | 2014-09-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin Structure, 22, 2014
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2NZ0
| Crystal structure of potassium channel Kv4.3 in complex with its regulatory subunit KChIP1 | Descriptor: | CALCIUM ION, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, ... | Authors: | Wang, H, Yan, Y, Shen, Y, Chen, L, Wang, K. | Deposit date: | 2006-11-22 | Release date: | 2006-12-26 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for modulation of Kv4 K(+) channels by auxiliary KChIP subunits. Nat.Neurosci., 10, 2007
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5OOL
| Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded interfacial rRNA | Descriptor: | 16S ribosomal RNA, 39S ribosomal protein L10, mitochondrial, ... | Authors: | Brown, A, Rathore, S, Kimanius, D, Aibara, S, Bai, X.C, Rorbach, J, Amunts, A, Ramakrishnan, V. | Deposit date: | 2017-08-08 | Release date: | 2017-09-13 | Last modified: | 2023-03-15 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structures of the human mitochondrial ribosome in native states of assembly. Nat. Struct. Mol. Biol., 24, 2017
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2I2R
| Crystal structure of the KChIP1/Kv4.3 T1 complex | Descriptor: | CALCIUM ION, Kv channel-interacting protein 1, Potassium voltage-gated channel subfamily D member 3, ... | Authors: | Findeisen, F, Pioletti, M, Minor Jr, D.L. | Deposit date: | 2006-08-16 | Release date: | 2006-10-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer Nat.Struct.Mol.Biol., 13, 2006
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2MDI
| Solution structure of the PP2WW mutant (KPP2WW) of HYPB | Descriptor: | Histone-lysine N-methyltransferase SETD2 | Authors: | Gao, Y.G, Hu, H.Y. | Deposit date: | 2013-09-10 | Release date: | 2014-09-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin. Structure, 22, 2014
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2LXL
| Lip5(mit)2 | Descriptor: | Vacuolar protein sorting-associated protein VTA1 homolog | Authors: | Skalicky, J.J, Sundquist, W.I. | Deposit date: | 2012-08-29 | Release date: | 2012-11-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Interactions of the Human LIP5 Regulatory Protein with Endosomal Sorting Complexes Required for Transport. J.Biol.Chem., 287, 2012
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2LEH
| Solution structure of the core SMN-Gemin2 complex | Descriptor: | Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1 | Authors: | Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G. | Deposit date: | 2011-06-15 | Release date: | 2012-06-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the core SMN-Gemin2 complex. Biochem.J., 445, 2012
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2N1O
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2Q5A
| human Pin1 bound to L-PEPTIDE | Descriptor: | 3,6,9,12,15,18-HEXAOXAICOSANE, Five residue peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Noel, J.P, Zhang, Y. | Deposit date: | 2007-05-31 | Release date: | 2007-06-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for high-affinity peptide inhibition of human Pin1. Acs Chem.Biol., 2, 2007
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7U0H
| State NE1 nucleolar 60S ribosome biogenesis intermediate - Overall model | Descriptor: | 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... | Authors: | Cruz, V.E, Sekulski, K, Peddada, N, Erzberger, J.P. | Deposit date: | 2022-02-18 | Release date: | 2022-12-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Sequence-specific remodeling of a topologically complex RNP substrate by Spb4. Nat.Struct.Mol.Biol., 29, 2022
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6P5W
| Structure of DCN1 bound to 3-methyl-N-((4S,5S)-3-methyl-6-oxo-1-phenyl-4-(p-tolyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide | Descriptor: | 3-methyl-N-[(4S,5S)-3-methyl-4-(4-methylphenyl)-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]benzamide, Lysozyme,DCN1-like protein 1 chimera | Authors: | Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A. | Deposit date: | 2019-05-31 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. J.Med.Chem., 62, 2019
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6P5V
| Structure of DCN1 bound to N-((4S,5S)-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-methylbenzamide | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Lysozyme,DCN1-like protein 1 fusion, N-[(4S,5S)-1-[(1S)-cyclohex-3-en-1-yl]-7-ethyl-4-(4-fluorophenyl)-3-methyl-6-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-3-methylbenzamide | Authors: | Guy, R.K, Kim, H.S, Hammill, J.T, Scott, D.C, Schulman, B.A. | Deposit date: | 2019-05-31 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.398 Å) | Cite: | Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation. J.Med.Chem., 62, 2019
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7P71
| The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6 | Descriptor: | CALCIUM ION, CITRIC ACID, GLYCEROL, ... | Authors: | Gogl, G, Cousido-Siah, A, Trave, G. | Deposit date: | 2021-07-19 | Release date: | 2022-07-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Quantitative fragmentomics allow affinity mapping of interactomes. Nat Commun, 13, 2022
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7X3X
| Cryo-EM structure of N1 nucleosome-RA | Descriptor: | DNA (146-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Lifei, L, Kangjing, C, Chen, Z. | Deposit date: | 2022-03-01 | Release date: | 2023-09-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of the ISW1a complex bound to the dinucleosome. Nat.Struct.Mol.Biol., 31, 2024
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7X3T
| Cryo-EM structure of ISW1a-dinucleosome | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (343-MER), ... | Authors: | Lifei, L, Kangjing, C, Chen, Z. | Deposit date: | 2022-03-01 | Release date: | 2023-09-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (5.4 Å) | Cite: | Structure of the ISW1a complex bound to the dinucleosome. Nat.Struct.Mol.Biol., 31, 2024
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7X3W
| Cryo-EM structure of ISW1-N1 nucleosome | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA (146-MER), ... | Authors: | Lifei, L, Kangjing, C, Chen, Z. | Deposit date: | 2022-03-01 | Release date: | 2023-09-20 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure of the ISW1a complex bound to the dinucleosome. Nat.Struct.Mol.Biol., 31, 2024
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4P0A
| Crystal structure of HOIP PUB domain in complex with p97 PIM | Descriptor: | E3 ubiquitin-protein ligase RNF31, Transitional endoplasmic reticulum ATPase | Authors: | Akutsu, M, Schaeffer, V, Olma, M.H, Gomes, L.C, Kawasaki, M, Dikic, I. | Deposit date: | 2014-02-20 | Release date: | 2014-05-07 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3001 Å) | Cite: | Binding of OTULIN to the PUB domain of HOIP controls NF-kappa B signaling. Mol.Cell, 54, 2014
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