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4WMW
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BU of 4wmw by Molmil
The structure of MBP-MCL1 bound to ligand 5 at 1.9A
Descriptor: 1,2-ETHANEDIOL, 2-hydroxy-5-(methylsulfanyl)benzoic acid, FORMIC ACID, ...
Authors:Clifton, M.C, Dranow, D.M.
Deposit date:2014-10-09
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Plos One, 10, 2015
7P3Y
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BU of 7p3y by Molmil
Homology model of the full-length AP-3 complex in an intermediate open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
7P3X
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BU of 7p3x by Molmil
Homology model of the full-length AP-3 complex in a compact open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
7P3Z
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BU of 7p3z by Molmil
Homology model of the full-length AP-3 complex in a stretched open conformation
Descriptor: AP complex subunit sigma, AP-3 complex subunit delta, AP-3 complex subunit mu, ...
Authors:Schubert, E, Raunser, S.
Deposit date:2021-07-09
Release date:2021-09-29
Last modified:2021-12-08
Method:ELECTRON MICROSCOPY (10.5 Å)
Cite:Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi.
J.Biol.Chem., 297, 2021
2RR2
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BU of 2rr2 by Molmil
Structure of O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor
Descriptor: Neurogenic locus notch homolog protein 1, alpha-L-fucopyranose
Authors:Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S.
Deposit date:2010-02-26
Release date:2010-10-13
Last modified:2020-07-29
Method:SOLUTION NMR
Cite:Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
4WRN
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BU of 4wrn by Molmil
Crystal structure of the polymerization region of human uromodulin/Tamm-Horsfall protein
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltose-binding periplasmic protein,Uromodulin, ZINC ION, ...
Authors:Bokhove, M, De Sanctis, D, Jovine, L.
Deposit date:2014-10-24
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A structured interdomain linker directs self-polymerization of human uromodulin.
Proc.Natl.Acad.Sci.USA, 113, 2016
4WVI
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BU of 4wvi by Molmil
Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with a substrate peptide (pep2).
Descriptor: Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, substrate peptide (pep2)
Authors:Young, P.G, Ting, Y.T, Baker, E.N.
Deposit date:2014-11-05
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
IUCrJ, 3, 2016
1ARV
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BU of 1arv by Molmil
CRYSTAL STRUCTURES OF CYANIDE-AND TRIIODIDE-BOUND FORMS OF ARTHROMYCES RAMOSUS PEROXIDASE AT DIFFERENT PH VALUES. PERTURBATIONS OF ACTIVE SITE RESIDUES AND THEIR IMPLICATION IN ENZYME CATALYSIS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYANIDE ION, ...
Authors:Fukuyama, K, Kunishima, N, Amada, F.
Deposit date:1995-04-25
Release date:1996-01-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of cyanide- and triiodide-bound forms of Arthromyces ramosus peroxidase at different pH values. Perturbations of active site residues and their implication in enzyme catalysis.
J.Biol.Chem., 270, 1995
4WMS
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BU of 4wms by Molmil
STRUCTURE OF APO MBP-MCL1 AT 1.9A
Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ...
Authors:Clifton, M.C, Dranow, D.M.
Deposit date:2014-10-09
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Plos One, 10, 2015
7P1G
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BU of 7p1g by Molmil
Structure of the P. aeruginosa ExoY-F-actin complex
Descriptor: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
Authors:Belyy, A, Merino, F, Raunser, S.
Deposit date:2021-07-01
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens.
Nat Commun, 12, 2021
2D2R
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BU of 2d2r by Molmil
Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase
Descriptor: Undecaprenyl Pyrophosphate Synthase
Authors:Kuo, C.J, Guo, R.T, Chen, C.L, Ko, T.P, Cheng, Y.S, Cheng, Y.L, Liang, P.H, Wang, A.H.-J.
Deposit date:2005-09-16
Release date:2006-09-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases.
J.Biomed.Biotechnol., 2008, 2008
7P1H
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BU of 7p1h by Molmil
Structure of the V. vulnificus ExoY-G-actin-profilin complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Belyy, A, Merino, F, Raunser, S.
Deposit date:2021-07-01
Release date:2021-11-17
Last modified:2021-12-01
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Mechanism of actin-dependent activation of nucleotidyl cyclase toxins from bacterial human pathogens.
Nat Commun, 12, 2021
1ARW
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BU of 1arw by Molmil
CRYSTAL STRUCTURES OF CYANIDE-AND TRIIODIDE-BOUND FORMS OF ARTHROMYCES RAMOSUS PEROXIDASE AT DIFFERENT PH VALUES. PERTURBATIONS OF ACTIVE SITE RESIDUES AND THEIR IMPLICATION IN ENZYME CATALYSIS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYANIDE ION, ...
Authors:Fukuyama, K, Kunishima, N, Amada, F.
Deposit date:1995-04-25
Release date:1996-01-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of cyanide- and triiodide-bound forms of Arthromyces ramosus peroxidase at different pH values. Perturbations of active site residues and their implication in enzyme catalysis.
J.Biol.Chem., 270, 1995
2D21
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BU of 2d21 by Molmil
NMR Structure of stereo-array isotope labelled (SAIL) maltodextrin-binding protein (MBP)
Descriptor: Maltose-binding periplasmic protein
Authors:Kainosho, M, Torizawa, T, Iwashita, Y, Terauchi, T, Ono, A.M, Guntert, P.
Deposit date:2005-09-02
Release date:2006-03-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Optimal isotope labelling for NMR protein structure determinations.
Nature, 440, 2006
6NEW
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BU of 6new by Molmil
Apo structure of the activated truncation of Vav1
Descriptor: Proto-oncogene vav, ZINC ION
Authors:Knapp, M.S, Elling, R.A, Ornelas, E.
Deposit date:2018-12-18
Release date:2019-12-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity
To Be Published
4WMX
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BU of 4wmx by Molmil
The structure of MBP-MCL1 bound to ligand 6 at 2.0A
Descriptor: 4-ethenyl-2-[(phenylsulfonyl)amino]benzoic acid, FORMIC ACID, MAGNESIUM ION, ...
Authors:Clifton, M.C, Dranow, D.M.
Deposit date:2014-10-09
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Plos One, 10, 2015
1ARU
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BU of 1aru by Molmil
CRYSTAL STRUCTURES OF CYANIDE-AND TRIIODIDE-BOUND FORMS OF ARTHROMYCES RAMOSUS PEROXIDASE AT DIFFERENT PH VALUES. PERTURBATIONS OF ACTIVE SITE RESIDUES AND THEIR IMPLICATION IN ENZYME CATALYSIS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYANIDE ION, ...
Authors:Fukuyama, K, Kunishima, N, Amada, F.
Deposit date:1995-04-25
Release date:1996-01-29
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of cyanide- and triiodide-bound forms of Arthromyces ramosus peroxidase at different pH values. Perturbations of active site residues and their implication in enzyme catalysis.
J.Biol.Chem., 270, 1995
1AVR
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BU of 1avr by Molmil
CRYSTAL AND MOLECULAR STRUCTURE OF HUMAN ANNEXIN V AFTER REFINEMENT. IMPLICATIONS FOR STRUCTURE, MEMBRANE BINDING AND ION CHANNEL FORMATION OF THE ANNEXIN FAMILY OF PROTEINS
Descriptor: ANNEXIN V, CALCIUM ION, SULFATE ION
Authors:Huber, R, Berendes, R, Burger, A, Schneider, M, Karshikov, A, Luecke, H, Roemisch, J, Paques, E.
Deposit date:1991-10-17
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins.
J.Mol.Biol., 223, 1992
6NF1
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BU of 6nf1 by Molmil
Vav1 inhibited by an allosteric inhibitor: Vav1 inhibitors block GEF activity
Descriptor: (2S)-3-[(3S)-1-(ethylsulfonyl)piperidin-3-yl]-2-{[3-(4-methylphenyl)imidazo[1,2-a]pyrazin-8-yl]amino}propan-1-ol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proto-oncogene vav, ...
Authors:Knapp, M.S, Elling, R.A, Ornelas, E.
Deposit date:2018-12-18
Release date:2019-12-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric Inhibitors of VAV1 Block Guanine Nucleotide Exchange Activity
To Be Published
4PE2
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BU of 4pe2 by Molmil
MBP PilA1 CD160
Descriptor: MALONATE ION, Maltose ABC transporter periplasmic protein,Prepilin-type N-terminal cleavage/methylation domain protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Piepenbrink, K.H, Sundberg, E.J.
Deposit date:2014-04-22
Release date:2015-01-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.724 Å)
Cite:Structural and Evolutionary Analyses Show Unique Stabilization Strategies in the Type IV Pili of Clostridium difficile.
Structure, 23, 2015
4WMV
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BU of 4wmv by Molmil
STRUCTURE OF MBP-MCL1 BOUND TO ligand 4 AT 2.4A
Descriptor: 3-chloro-6-fluoro-1-benzothiophene-2-carboxylic acid, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Clifton, M.C, Moulin, A.
Deposit date:2014-10-09
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Plos One, 10, 2015
4WVJ
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BU of 4wvj by Molmil
Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with an inhibitor peptide (pep3).
Descriptor: Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, inhibitor peptide (PEP3)
Authors:Young, P.G, Ting, Y.T, Baker, E.N.
Deposit date:2014-11-05
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization.
IUCrJ, 3, 2016
1A7L
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BU of 1a7l by Molmil
DOMINANT B-CELL EPITOPE FROM THE PRES2 REGION OF HEPATITIS B VIRUS IN THE FORM OF AN INSERTED PEPTIDE SEGMENT IN MALTODEXTRIN-BINDING PROTEIN
Descriptor: MALE-B363, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Saul, F.A, Vulliez-Lenormand, B, Lema, F, Bentley, G.A.
Deposit date:1998-03-16
Release date:1998-06-17
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a dominant B-cell epitope from the preS2 region of hepatitis B virus in the form of an inserted peptide segment in maltodextrin-binding protein.
J.Mol.Biol., 280, 1998
1ANX
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BU of 1anx by Molmil
THE CRYSTAL STRUCTURE OF A NEW HIGH-CALCIUM FORM OF ANNEXIN V
Descriptor: ANNEXIN V, CALCIUM ION, SULFATE ION
Authors:Sopkova, J, Renouard, M, Lewit-Bentley, A.
Deposit date:1993-10-26
Release date:1994-12-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of a new high-calcium form of annexin V.
J.Mol.Biol., 234, 1993
4WMT
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BU of 4wmt by Molmil
STRUCTURE OF MBP-MCL1 BOUND TO ligand 1 AT 2.35A
Descriptor: 1,2-ETHANEDIOL, 7-[2-(1H-imidazol-1-yl)-4-methylpyridin-3-yl]-3-[3-(naphthalen-1-yloxy)propyl]-1-[2-oxo-2-(piperazin-1-yl)ethyl]-1H-indole-2-carboxylic acid, FORMIC ACID, ...
Authors:Clifton, M.C, Dranow, D.M.
Deposit date:2014-10-09
Release date:2015-05-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Plos One, 10, 2015

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