4WMT

STRUCTURE OF MBP-MCL1 BOUND TO ligand 1 AT 2.35A

Summary for 4WMT

• Entry DOI: 10.2210/pdb4wmt/pdb
• Related: 4WMR 4WMS 4WMU 4WMV 4WMW 4WMX
• Related PRD ID: PRD_900001
• Descriptor: MBP-MCL1 chimera protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 7-[2-(1H-imidazol-1-yl)-4-methylpyridin-3-yl]-3-[3-(naphthalen-1-yloxy)propyl]-1-[2-oxo-2-(piperazin-1-yl)ethyl]-1H-indole-2-carboxylic acid, ... (6 entities in total)
• Functional Keywords: apoptosis, protein-protein interaction
• Biological source: Escherichia coli; More
• Total number of polymer chains: 1
• Total formula weight: 58850.24

Authors

Clifton, M.C.,Dranow, D.M. (deposition date: 2014-10-09, release date: 2015-05-06, Last modification date: 2023-09-27)

• Primary citation: Clifton, M.C.,Dranow, D.M.,Leed, A.,Fulroth, B.,Fairman, J.W.,Abendroth, J.,Atkins, K.A.,Wallace, E.,Fan, D.,Xu, G.,Ni, Z.J.,Daniels, D.,Van Drie, J.,Wei, G.,Burgin, A.B.,Golub, T.R.,Hubbard, B.K.,Serrano-Wu, M.H.; A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.; Plos One, 10:e0125010-e0125010, 2015; PubMed: 25909780; DOI: 10.1371/journal.pone.0125010

Experimental method

X-RAY DIFFRACTION (2.35 Å)