PDB: 38 件ウェブページステータス検索Chemie searchBIRD

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2VDD	Crystal Structure of the Open State of TolC Outer Membrane Component of Mutlidrug Efflux Pumps 分子名称: CHLORIDE ION, OUTER MEMBRANE PROTEIN TOLC, POTASSIUM ION 著者 Bavro, V.N, Pietras, Z, Furnham, N, Perez-Cano, L, Fernandez-Recio, J, Pei, X.Y, Truer, R, Misra, R, Luisi, B. 登録日 2007-10-04 公開日 2008-04-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Assembly and Channel Opening in a Bacterial Drug Efflux Machine. Mol.Cell, 30, 2008
5AZS	Crystal structure of a membrane protein from Pseudomonas aeruginosa 分子名称: Outer membrane protein OprJ 著者 Yonehara, R, Yamashita, E, Nakagawa, A. 登録日 2015-10-21 公開日 2016-06-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structures of OprN and OprJ, outer membrane factors of multidrug tripartite efflux pumps of Pseudomonas aeruginosa. Proteins, 84, 2016
2WMZ	Structure of a mutated TolC 分子名称: CHLORIDE ION, OUTER MEMBRANE PROTEIN TOLC, SODIUM ION, ... 著者 Hinchliffe, P, Pei, X.Y, Symmons, M.F, Koronakis, E, Hughes, C, Koronakis, V. 登録日 2009-07-03 公開日 2011-01-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of Sequential Open States in a Symmetrical Opening Transition of the Tolc Exit Duct. Proc.Natl.Acad.Sci.USA, 108, 2011
2XMN	High resolution snapshots of defined TolC open states present an iris- like movement of periplasmic entrance helices 分子名称: CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Outer membrane protein TolC 著者 Pei, X.Y, Koronakis, E, Hughes, C, Koronakis, V. 登録日 2010-07-28 公開日 2011-01-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structures of sequential open states in a symmetrical opening transition of the TolC exit duct. Proc. Natl. Acad. Sci. U.S.A., 108, 2011
5V5S	multi-drug efflux; membrane transport; RND superfamily; Drug resistance 分子名称: Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, Outer membrane protein TolC 著者 wang, Z, fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. 登録日 2017-03-15 公開日 2017-04-19 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump. Elife, 6, 2017
5O66	Asymmetric AcrABZ-TolC 分子名称: Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB, ... 著者 Du, D, Luisi, B.F. 登録日 2017-06-05 公開日 2017-06-14 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump. Elife, 6, 2017
6IOL	Cryo-EM structure of multidrug efflux pump MexAB-OprM (60 degree state) 分子名称: Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM 著者 Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E. 登録日 2018-10-30 公開日 2019-04-03 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.76 Å) 主引用文献 Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism. Nat Commun, 10, 2019
6IOK	Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) 分子名称: Multidrug resistance protein MexA, Multidrug resistance protein MexB, Outer membrane protein OprM 著者 Tsutsumi, K, Yonehara, R, Nakagawa, A, Yamashita, E. 登録日 2018-10-30 公開日 2019-04-03 最終更新日 2019-04-17 実験手法 ELECTRON MICROSCOPY (3.64 Å) 主引用文献 Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism. Nat Commun, 10, 2019
6TA6	MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs 分子名称: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM 著者 Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. 登録日 2019-10-29 公開日 2020-09-16 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
6TA5	OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs 分子名称: Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM 著者 Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. 登録日 2019-10-29 公開日 2020-09-16 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
5NIK	Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump 分子名称: Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC 著者 Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D. 登録日 2017-03-24 公開日 2017-05-24 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump. Nat Microbiol, 2, 2017
5NIL	Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump-MacB section 分子名称: Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC 著者 Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D. 登録日 2017-03-24 公開日 2017-05-24 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (5.3 Å) 主引用文献 Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump. Nat Microbiol, 2, 2017
5NG5	multi-drug efflux; membrane transport; RND superfamily; Drug resistance 分子名称: 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ... 著者 Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. 登録日 2017-03-16 公開日 2017-04-19 最終更新日 2017-08-02 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump. Elife, 6, 2017

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