7MDE
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![BU of 7mde by Molmil](/molmil-images/mine/7mde) | Full-length S95A ClbP | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... | Authors: | Velilla, J.A, Volpe, M.R, Gaudet, R. | Deposit date: | 2021-04-04 | Release date: | 2022-09-28 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of colibactin activation by the ClbP peptidase. Nat.Chem.Biol., 19, 2023
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7MDF
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![BU of 7mdf by Molmil](/molmil-images/mine/7mdf) | Full-length S95A ClbP bound to N-acyl-D-asparagine analog | Descriptor: | (2S)-2,3-dihydroxypropyl (9Z)-hexadec-9-enoate, Beta-lactamase, CHLORIDE ION, ... | Authors: | Velilla, J.A, Volpe, M.R, Gaudet, R. | Deposit date: | 2021-04-04 | Release date: | 2022-09-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis of colibactin activation by the ClbP peptidase. Nat.Chem.Biol., 19, 2023
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3ZYT
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![BU of 3zyt by Molmil](/molmil-images/mine/3zyt) | |
4BLM
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![BU of 4blm by Molmil](/molmil-images/mine/4blm) | |
5JOC
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![BU of 5joc by Molmil](/molmil-images/mine/5joc) | Crystal structure of the S61A mutant of AmpC BER | Descriptor: | Beta-lactamase, CITRIC ACID | Authors: | Na, J.H, An, Y.J, Cha, S.S. | Deposit date: | 2016-05-02 | Release date: | 2017-05-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural basis for the extended substrate spectrum of AmpC BER and structure-guided discovery of the inhibition activity of citrate against the class C beta-lactamases AmpC BER and CMY-10. Acta Crystallogr D Struct Biol, 72, 2016
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5K1F
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![BU of 5k1f by Molmil](/molmil-images/mine/5k1f) | Crystal structure of a class C beta lactamase/compound2 complex | Descriptor: | Beta-lactamase, CADMIUM ION, INOSINIC ACID | Authors: | An, Y.J, Na, J.H, Cha, S.S. | Deposit date: | 2016-05-18 | Release date: | 2017-05-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | GMP and IMP Are Competitive Inhibitors of CMY-10, an Extended-Spectrum Class C beta-Lactamase. Antimicrob. Agents Chemother., 61, 2017
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2BLS
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![BU of 2bls by Molmil](/molmil-images/mine/2bls) | |
8SDR
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![BU of 8sdr by Molmil](/molmil-images/mine/8sdr) | |
8SDN
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![BU of 8sdn by Molmil](/molmil-images/mine/8sdn) | Crystal structure of PDC-3 Y221H beta-lactamase | Descriptor: | Beta-lactamase, ISOPROPYL ALCOHOL | Authors: | Kumar, V, van den Akker, F. | Deposit date: | 2023-04-07 | Release date: | 2023-08-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase. Antimicrob.Agents Chemother., 67, 2023
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8SDV
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![BU of 8sdv by Molmil](/molmil-images/mine/8sdv) | Crystal structure of PDC-3 Y221H beta-lactamase in complex with the boronic acid inhibitor S02030 | Descriptor: | 1-{(2R)-2-(dihydroxyboranyl)-2-[(thiophen-2-ylacetyl)amino]ethyl}-1H-1,2,3-triazole-4-carboxylic acid, Beta-lactamase, DIMETHYL SULFOXIDE, ... | Authors: | Kumar, V, van den Akker, F. | Deposit date: | 2023-04-07 | Release date: | 2023-08-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase. Antimicrob.Agents Chemother., 67, 2023
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8SDT
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8SDL
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![BU of 8sdl by Molmil](/molmil-images/mine/8sdl) | Crystal structure of PDC-3 beta-lactamase | Descriptor: | Beta-lactamase, IMIDAZOLE, ISOPROPYL ALCOHOL | Authors: | Kumar, V, van den Akker, F. | Deposit date: | 2023-04-07 | Release date: | 2023-08-16 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Natural protein engineering in the Omega-loop: the role of Y221 in ceftazidime and ceftolozane resistance in Pseudomonas -derived cephalosporinase. Antimicrob.Agents Chemother., 67, 2023
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8SDS
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2DCF
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![BU of 2dcf by Molmil](/molmil-images/mine/2dcf) | Crystal structure of 6-aminohexanoate-dimer hydrolase S112A/G181D/H266N mutant with substrate | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-AMINOHEXANOIC ACID, 6-aminohexanoate-dimer hydrolase, ... | Authors: | Ohki, T, Shibata, N, Higuchi, Y, Takeo, M, Negoro, S. | Deposit date: | 2006-01-06 | Release date: | 2007-01-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Nylon-oligomer degrading enzyme/substrate complex: catalytic mechanism of 6-aminohexanoate-dimer hydrolase J.Mol.Biol., 370, 2007
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2BLM
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5K1D
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![BU of 5k1d by Molmil](/molmil-images/mine/5k1d) | Crystal structure of a class C beta lactamase/compound1 complex | Descriptor: | Beta-lactamase, CADMIUM ION, GUANOSINE-5'-MONOPHOSPHATE | Authors: | AN, Y.J, Na, J.H, Cha, S.S. | Deposit date: | 2016-05-18 | Release date: | 2017-05-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | GMP and IMP Are Competitive Inhibitors of CMY-10, an Extended-Spectrum Class C beta-Lactamase. Antimicrob. Agents Chemother., 61, 2017
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2DRW
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![BU of 2drw by Molmil](/molmil-images/mine/2drw) | The crystal structutre of D-amino acid amidase from Ochrobactrum anthropi SV3 | Descriptor: | BARIUM ION, D-Amino acid amidase | Authors: | Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. | Deposit date: | 2006-06-15 | Release date: | 2006-07-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins J.Mol.Biol., 368, 2007
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2DNS
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![BU of 2dns by Molmil](/molmil-images/mine/2dns) | The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with D-Phenylalanine | Descriptor: | BARIUM ION, D-PHENYLALANINE, D-amino acid amidase | Authors: | Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. | Deposit date: | 2006-04-26 | Release date: | 2006-05-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins J.Mol.Biol., 368, 2007
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8TTP
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![BU of 8ttp by Molmil](/molmil-images/mine/8ttp) | Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 1,2-ETHANEDIOL, Beta-lactamase, ... | Authors: | Chang, C, Maltseva, N, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | Deposit date: | 2023-08-14 | Release date: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Crystal structure of class C beta-lactamase from Escherichia coli in complex with avibactam to be published
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5LWF
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![BU of 5lwf by Molmil](/molmil-images/mine/5lwf) | Structure of a single domain camelid antibody fragment cAb-G10S in complex with the BlaP beta-lactamase from Bacillus licheniformis | Descriptor: | ACETATE ION, Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-G10S | Authors: | Vettore, N, Kerff, F, Pain, C, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M. | Deposit date: | 2016-09-16 | Release date: | 2017-11-15 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments To Be Published
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2E8I
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![BU of 2e8i by Molmil](/molmil-images/mine/2e8i) | Structure of 6-aminohexanoate-dimer hydrolase, D1 mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-aminohexanoate-dimer hydrolase, GLYCEROL, ... | Authors: | Shibata, N, Higuchi, Y, Negoro, S. | Deposit date: | 2007-01-20 | Release date: | 2008-01-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a beta-lactamase fold. Febs J., 276, 2009
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2EFX
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![BU of 2efx by Molmil](/molmil-images/mine/2efx) | The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with L-phenylalanine amide | Descriptor: | BARIUM ION, D-amino acid amidase, PHENYLALANINE AMIDE | Authors: | Okazaki, S, Suzuki, A, Mizushima, T, Komeda, H, Asano, Y, Yamane, T. | Deposit date: | 2007-02-26 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3. Acta Crystallogr.,Sect.D, 64, 2008
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2EFU
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![BU of 2efu by Molmil](/molmil-images/mine/2efu) | The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with L-phenylalanine | Descriptor: | BARIUM ION, D-Amino acid amidase, PHENYLALANINE | Authors: | Okazaki, S, Suzuki, A, Mizushima, T, Komeda, H, Asano, Y, Yamane, T. | Deposit date: | 2007-02-26 | Release date: | 2007-03-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3. Acta Crystallogr.,Sect.D, 64, 2008
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1S6R
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![BU of 1s6r by Molmil](/molmil-images/mine/1s6r) | 908R class c beta-lactamase bound to iodo-acetamido-phenyl boronic acid | Descriptor: | 4-IODO-ACETAMIDO PHENYLBORONIC ACID, beta-lactamase | Authors: | Wouters, J. | Deposit date: | 2004-01-27 | Release date: | 2004-02-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Crystal structure of Enterobacter cloacae 908R class C beta-lactamase bound to iodo-acetamido-phenyl boronic acid, a transition-state analogue. Cell.Mol.Life Sci., 60, 2003
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1SDE
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![BU of 1sde by Molmil](/molmil-images/mine/1sde) | Toward Better Antibiotics: Crystal Structure Of D-Ala-D-Ala Peptidase inhibited by a novel bicyclic phosphate inhibitor | Descriptor: | 2-[(DIOXIDOPHOSPHINO)OXY]BENZOATE, D-alanyl-D-alanine carboxypeptidase, GLYCEROL | Authors: | Silvaggi, N.R, Kaur, K, Adediran, S.A, Pratt, R.F, Kelly, J.A. | Deposit date: | 2004-02-13 | Release date: | 2004-10-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Toward better antibiotics: crystallographic studies of a novel class of DD-peptidase/beta-lactamase inhibitors Biochemistry, 43, 2004
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