2QTH
| Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus in complex with GDP | Descriptor: | ACETATE ION, CADMIUM ION, GTP-binding protein, ... | Authors: | Wu, H, Sun, L, Brouns, S.J, Fu, S, Rao, Z, Van der Oost, J. | Deposit date: | 2007-08-02 | Release date: | 2008-08-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a GTP-binding protein from the hyperthermophilic archaeon Sulfolobus solfataricus. To be Published
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2QTI
| Crystal structure of the UPF0352 protein SO_2176 from Shewanella oneidensis. NESG target SoR77. | Descriptor: | UPF0352 protein SO_2176 | Authors: | Vorobiev, S.M, Su, M, Seetharaman, J, Kuzin, A.P, Wang, D, Cunningham, K, Owens, L, Maglaqui, M, Fang, Y, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-08-02 | Release date: | 2007-08-21 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the UPF0352 protein SO_2176 from Shewanella oneidensis. To be Published
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2QTJ
| Solution structure of human dimeric immunoglobulin A | Descriptor: | Ig alpha-1 chain C region, Kappa light chain IgA1 | Authors: | Bonner, A, Furtado, P.B, Almogren, A, Kerr, M.A, Perkins, S.J. | Deposit date: | 2007-08-02 | Release date: | 2008-01-22 | Last modified: | 2024-02-21 | Method: | SOLUTION SCATTERING | Cite: | Implications of the near-planar solution structure of human myeloma dimeric IgA1 for mucosal immunity and IgA nephropathy J.Immunol., 180, 2008
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2QTK
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2QTL
| Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase | Authors: | Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S. | Deposit date: | 2007-08-02 | Release date: | 2007-11-13 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry, 46, 2007
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2QTM
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2QTN
| Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase | Descriptor: | GLYCEROL, MAGNESIUM ION, NICOTINATE MONONUCLEOTIDE, ... | Authors: | Sershon, V.C, Santarsiero, B.D, Mesecar, A.D. | Deposit date: | 2007-08-02 | Release date: | 2008-07-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Kinetic and X-ray structural evidence for negative cooperativity in substrate binding to nicotinate mononucleotide adenylyltransferase (NMAT) from Bacillus anthracis. J.Mol.Biol., 385, 2009
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2QTO
| An anisotropic model for potassium channel KcsA | Descriptor: | POTASSIUM ION, Voltage-gated potassium channel | Authors: | Chen, X, Poon, B.K, Dousis, A, Wang, Q, Ma, J. | Deposit date: | 2007-08-02 | Release date: | 2007-09-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | Normal-mode refinement of anisotropic thermal parameters for potassium channel KcsA at 3.2 A crystallographic resolution Structure, 15, 2007
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2QTP
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2QTQ
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2QTR
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2QTS
| Structure of an acid-sensing ion channel 1 at 1.9 A resolution and low pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel, CHLORIDE ION, ... | Authors: | Jasti, J, Furukawa, H, Gonzales, E.B, Gouaux, E. | Deposit date: | 2007-08-02 | Release date: | 2007-09-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of acid-sensing ion channel 1 at 1.9A resolution and low pH Nature, 449, 2007
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2QTT
| Crystal Structure of Arabidopsis thaliana 5'-Methylthioadenosine nucleosidase in complex with Formycin A | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, 1,2-ETHANEDIOL, 5'-methylthioadenosine nucleosidase, ... | Authors: | Siu, K.K.W, Howell, P.L. | Deposit date: | 2007-08-02 | Release date: | 2008-04-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Molecular determinants of substrate specificity in plant 5'-methylthioadenosine nucleosidases. J.Mol.Biol., 378, 2008
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2QTU
| Estrogen receptor beta ligand-binding domain complexed to a benzopyran ligand | Descriptor: | (3aS,4R,9bR)-2,2-difluoro-4-(4-hydroxyphenyl)-6-(methoxymethyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol, Estrogen receptor beta | Authors: | Richardson, T.I, Dodge, J.A, Wang, Y, Durbin, J.D, Krishnan, V, Norman, B.H. | Deposit date: | 2007-08-02 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.53 Å) | Cite: | Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies. Bioorg.Med.Chem.Lett., 17, 2007
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2QTV
| Structure of Sec23-Sar1 complexed with the active fragment of Sec31 | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein transport protein SEC23, ... | Authors: | Goldberg, J, Bi, X, Mancias, J.D. | Deposit date: | 2007-08-02 | Release date: | 2008-01-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31. Dev.Cell, 13, 2007
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2QTW
| The Crystal Structure of PCSK9 at 1.9 Angstroms Resolution Reveals structural homology to Resistin within the C-terminal domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Proprotein convertase subtilisin/kexin type 9, ... | Authors: | Hampton, E.N, Knuth, M.W, Li, J, Harris, J.L, Lesley, S.A, Spraggon, G. | Deposit date: | 2007-08-02 | Release date: | 2007-09-18 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QTX
| Crystal structure of an Hfq-like protein from Methanococcus jannaschii | Descriptor: | Uncharacterized protein MJ1435 | Authors: | Nielsen, J.S, Boggild, A, Andersen, C.B.F, Nielsen, G, Boysen, A, Brodersen, D.E, Valentin-Hansen, P. | Deposit date: | 2007-08-03 | Release date: | 2007-11-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | An Hfq-like protein in archaea: Crystal structure and functional characterization of the Sm protein from Methanococcus jannaschii. Rna, 13, 2007
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2QTY
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2QTZ
| Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S. | Deposit date: | 2007-08-02 | Release date: | 2007-11-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry, 46, 2007
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2QU0
| Crystal structure determination of sheep methemoglobin at 2.7 Angstrom resolution | Descriptor: | Hemoglobin subunit alpha-1/2, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Neelagandan, K, Sathya Moorthy, Pon, Balasubramanian, M, Sundaresan, S, Ponnuswamy, M.N. | Deposit date: | 2007-08-03 | Release date: | 2008-08-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure determination of sheep(Ovis aries) methemoglobin at 2.7 angstrom resolution To be Published
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2QU1
| Crystal Structure of a Cyclized GFP Variant | Descriptor: | CALCIUM ION, Green fluorescent protein | Authors: | Bailey, L.J, McCoy, J.G, Bitto, E, Bingman, C.A, Fox, B.G, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-08-03 | Release date: | 2007-09-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of a Cyclized GFP Variant. To be Published
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2QU2
| BACE1 with Compound 1 | Descriptor: | Beta-secretase 1, N-[amino(imino)methyl]-2-(2,5-diphenyl-1H-pyrrol-1-yl)acetamide | Authors: | Chopra, R. | Deposit date: | 2007-08-03 | Release date: | 2008-08-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Thiophene substituted acylguanidines as BACE1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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2QU3
| BACE1 with Compound 2 | Descriptor: | Beta-secretase 1, N-[amino(imino)methyl]-2-[2-(2-chlorophenyl)-4-(4-propoxyphenyl)-3-thienyl]acetamide | Authors: | Chopra, R. | Deposit date: | 2007-08-03 | Release date: | 2008-08-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Thiophene substituted acylguanidines as BACE1 inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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2QU4
| Model for Bacterial ParM Filament | Descriptor: | Plasmid segregation protein parM | Authors: | Orlova, A, Garner, E.C, Galkin, V.E, Heuser, J, Mullins, R.D, Egelman, E.H. | Deposit date: | 2007-08-03 | Release date: | 2007-09-18 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (16 Å) | Cite: | The structure of bacterial ParM filaments. Nat.Struct.Mol.Biol., 14, 2007
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2QU5
| Crystal structure of the VEGFR2 kinase domain in complex with a benzimidazole inhibitor | Descriptor: | 4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide, Vascular endothelial growth factor receptor 2 | Authors: | Whittington, D.A, Kim, J.L, Long, A.M, Rose, P, Gu, Y, Zhao, H. | Deposit date: | 2007-08-03 | Release date: | 2007-09-25 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors. J.Med.Chem., 50, 2007
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