8EI5
 
 | | Crystal structure of the WWP2 HECT domain in complex with H301, a Helicon Polypeptide | | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, H301, ... | | Authors: | Li, K, Tokareva, O.S, Thomson, T.M, Verdine, G.L, McGee, J.H. | | Deposit date: | 2022-09-14 | | Release date: | 2023-10-25 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides.
Nat Commun, 14, 2023
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3ZIO
 | | minor-site specific NLS (A28) | | Descriptor: | A28NLS, IMPORTIN SUBUNIT ALPHA-2 | | Authors: | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | | Deposit date: | 2013-01-10 | | Release date: | 2013-08-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
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3ZIN
 | | Gu_alpha_helicase | | Descriptor: | IMPORTIN SUBUNIT ALPHA-2, NUCLEOLAR RNA HELICASE 2 | | Authors: | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | | Deposit date: | 2013-01-10 | | Release date: | 2013-08-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
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2JT0
 | | Solution structure of F104W cardiac troponin C | | Descriptor: | Troponin C, slow skeletal and cardiac muscles | | Authors: | Wang, X, Mercier, P, Letourneau, P.-J, Sykes, B.D. | | Deposit date: | 2007-07-17 | | Release date: | 2008-05-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Effects of Phe-to-Trp mutation and fluorotryptophan incorporation on the solution structure of cardiac troponin C, and analysis of its suitability as a potential probe for in situ NMR studies.
Protein Sci., 14, 2005
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3ZKY
 | | Isopenicillin N synthase with substrate analogue AhCmC | | Descriptor: | FE (III) ION, GLYCEROL, ISOPENICILLIN N SYNTHASE, ... | | Authors: | Daruzzaman, A, Clifton, I.J, Rutledge, P.J. | | Deposit date: | 2013-01-25 | | Release date: | 2013-03-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The Interaction of Isopenicillin N Synthase with Homologated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Homocysteinyl-D-Xaa Characterised by Protein Crystallography.
Chembiochem, 14, 2013
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3ZOX
 | | Crystal Structure of N64Del Mutant of Nitrosomonas europaea Cytochrome c552 (monoclinic space group) | | Descriptor: | CYTOCHROME C-552, HEME C | | Authors: | Hersleth, H.-P, Can, M, Krucinska, J, Zoppellaro, G, Andersen, N.H, Wedekind, J.E, Andersson, K.K, Bren, K.L. | | Deposit date: | 2013-02-26 | | Release date: | 2013-08-14 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Characterization of Nitrosomonas Europaea Cytochrome C-552 Variants with Marked Differences in Electronic Structure.
Chembiochem, 14, 2013
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3RIE
 | | The structure of Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N-(3-aminopropyl)-trans-cyclohexane-1,4-diamine | | Descriptor: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, ... | | Authors: | Williams, M, Sprenger, J, Persson, L, Louw, A.I, Birkholtz, L, Al-Karadaghi, S. | | Deposit date: | 2011-04-13 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A novel inhibitor of Plasmodium falciparum spermidine synthase: a twist in the tail.
Malar J, 14, 2015
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3ZHB
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3ZIR
 | | minor-site specific NLS (B141) | | Descriptor: | B141NLS, IMPORTIN SUBUNIT ALPHA-2 | | Authors: | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | | Deposit date: | 2013-01-10 | | Release date: | 2013-08-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
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3RBQ
 | | Co-crystal structure of human UNC119 (retina gene 4) and an N-terminal Transducin-alpha mimicking peptide | | Descriptor: | Guanine nucleotide-binding protein G(t) subunit alpha-1, Protein unc-119 homolog A | | Authors: | Constantine, R, Whitby, F.G, Hill, C.P, Baehr, W. | | Deposit date: | 2011-03-29 | | Release date: | 2011-06-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | UNC119 is required for G protein trafficking in sensory neurons.
Nat.Neurosci., 14, 2011
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2M08
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2N10
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2N13
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4BWA
 | | PylRS Y306G, Y384F, I405R mutant in complex with adenylated norbornene | | Descriptor: | 1,2-ETHANEDIOL, Adenylated Norbornene, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Schneider, S, Vrabel, M, Gattner, M.J, Fluegel, V, Lopez-Carillo, V, Carell, T. | | Deposit date: | 2013-07-01 | | Release date: | 2013-07-31 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural Insights Into Incorporation of Norbornene Amino Acids for Click Modification of Proteins
Chem.Bio.Chem., 14, 2013
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2N0Z
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4B32
 | | Humanised monomeric RadA in complex with napht-1-ol | | Descriptor: | DNA REPAIR AND RECOMBINATION PROTEIN RADA, PHOSPHATE ION, naphthalen-2-ol | | Authors: | Scott, D.E, Ehebauer, M.T, Pukala, T, Marsh, M, Blundell, T.L, Venkitaraman, A.R, Abell, C, Hyvonen, M. | | Deposit date: | 2012-07-20 | | Release date: | 2013-02-06 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Using a Fragment-Based Approach to Target Protein-Protein Interactions.
Chembiochem, 14, 2013
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2KAY
 | | Solution structure and dynamics of S100A5 in the Ca2+ -bound states | | Descriptor: | CALCIUM ION, Protein S100-A5 | | Authors: | Bertini, I, Das Gupta, S, Hu, X, Karavelas, T, Luchinat, C, Parigi, G, Yuan, J, Structural Proteomics in Europe (SPINE), Structural Proteomics in Europe 2 (SPINE-2) | | Deposit date: | 2008-11-17 | | Release date: | 2009-06-30 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution structure and dynamics of S100A5 in the apo and Ca2+-bound states
J.Biol.Inorg.Chem., 14, 2009
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4BPJ
 | | Mcl-1 bound to alpha beta Puma BH3 peptide 3 | | Descriptor: | ALPHA BETA BH3-PEPTIDE, CHLORIDE ION, FUSION PROTEIN CONSISTING OF INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 HOMOLOG, ... | | Authors: | Smith, B.J, Lee, E.F, Checco, J.W, Gellman, S.H, Fairlie, W.D. | | Deposit date: | 2013-05-27 | | Release date: | 2014-04-09 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.599 Å) | | Cite: | Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
Chembiochem, 14, 2013
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4BPI
 | | Mcl-1 bound to alpha beta Puma BH3 peptide 2 | | Descriptor: | ALPHA BETA BH3PEPTIDE, CADMIUM ION, FUSION PROTEIN CONSISTING OF INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN MCL-1 HOMOLOG | | Authors: | Smith, B.J, Lee, E.F, Checco, J.W, Gellman, S.H, Fairlie, W.D. | | Deposit date: | 2013-05-27 | | Release date: | 2014-04-09 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.982 Å) | | Cite: | Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
Chembiochem, 14, 2013
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4BPK
 | | Bcl-xL bound to alpha beta Puma BH3 peptide 5 | | Descriptor: | 1,2-ETHANEDIOL, ALPHA BETA BH3-PEPTIDE, BCL-2-LIKE PROTEIN 1, ... | | Authors: | Smith, B.J, Lee, E.F, Checco, J.W, Gellman, S.H, Fairlie, W.D. | | Deposit date: | 2013-05-27 | | Release date: | 2014-04-09 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (1.756 Å) | | Cite: | Structure-Guided Rational Design of Alpha/Beta-Peptide Foldamers with High Affinity for Bcl-2 Family Prosurvival Proteins.
Chembiochem, 14, 2013
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4C0J
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains in the apo state (Apo-MiroS) | | Descriptor: | L-HOMOSERINE, MITOCHONDRIAL RHO GTPASE, SODIUM ION, ... | | Authors: | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | Deposit date: | 2013-08-05 | | Release date: | 2013-10-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.82 Å) | | Cite: | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
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4C0K
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one calcium ion (Ca-MiroS) | | Descriptor: | CALCIUM ION, L-HOMOSERINE, MITOCHONDRIAL RHO GTPASE, ... | | Authors: | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | Deposit date: | 2013-08-05 | | Release date: | 2013-10-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.801 Å) | | Cite: | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
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4C0L
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one magnesium ion and Mg:GDP (MgGDP-MiroS) | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, L-HOMOSERINE, MAGNESIUM ION, ... | | Authors: | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | Deposit date: | 2013-08-05 | | Release date: | 2013-10-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
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2NRY
 | | Crystal structure of IRAK-4 | | Descriptor: | STAUROSPORINE, interleukin-1 receptor-associated kinase 4 | | Authors: | Wang, Z, Liu, J, Walker, N.P.C. | | Deposit date: | 2006-11-02 | | Release date: | 2006-12-12 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper.
Structure, 14, 2006
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2NZ4
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