2NRY

Crystal structure of IRAK-4

Summary for 2NRY

• Entry DOI: 10.2210/pdb2nry/pdb
• Related: 2NRU
• Descriptor: interleukin-1 receptor-associated kinase 4, STAUROSPORINE (3 entities in total)
• Functional Keywords: kinase, inhibitor, staurosporine, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 139858.04

Authors

Wang, Z.,Liu, J.,Walker, N.P.C. (deposition date: 2006-11-02, release date: 2006-12-12, Last modification date: 2023-12-27)

• Primary citation: Wang, Z.,Liu, J.,Sudom, A.,Ayres, M.,Li, S.,Wesche, H.,Powers, J.P.,Walker, N.P.C.; Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper.; Structure, 14:1835-1844, 2006; PubMed: 17161373; DOI: 10.1016/j.str.2006.11.001

Experimental method

X-RAY DIFFRACTION (2.15 Å)