2NRY
Crystal structure of IRAK-4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | interleukin-1 receptor-associated kinase 4 | polymer | 307 | 34498.0 | 4 | UniProt (Q9NWZ3) Pfam (PF07714) | Homo sapiens (human) | IRAK-4, NY- REN-64 antigen |
| 2 | E, F, G, H (A, B, C, D) | STAUROSPORINE | non-polymer | 466.5 | 4 | Chemie (STU) PubChem (71203703) PubChem (42610657) PubChem (44299148) PubChem (49831000) PubChem (25322871) PubChem (28684983) PubChem (44120114) PubChem (44537813) PubChem (46864193) PubChem (358479) PubChem (5280487) PubChem (5311103) PubChem (6711321) PubChem (9956178) PubChem (68262703) PubChem (68306294) PubChem (73953205) PubChem (12046017) PubChem (86306248) PubChem (5279) PubChem (44259) PubChem (451705) PubChem (122130844) PubChem (5459111) PubChem (6419748) PubChem (9804568) PubChem (9937179) PubChem (143163481) PubChem (143224059) PubChem (143494026) PubChem (162978898) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 402 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 154 - 460 (UniProt: Q9NWZ3)
| PDB | External Database | Details |
|---|---|---|
| Tpo 345 | Thr 345 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 137991.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1866.1 | |
| All* | Total formula weight | 139858.0 |
