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7ECF
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BU of 7ecf by Molmil
Crystal Structure of d(G4C2)2-Ba in C2221 space group
Descriptor: BARIUM ION, DNA (5'-D(*GP*GP*GP*GP*CP*CP*GP*GP*GP*GP*CP*C)-3')
Authors:Geng, Y, Liu, C, Cai, Q, Luo, Z, Zhu, G.
Deposit date:2021-03-12
Release date:2021-06-09
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of parallel G-quadruplex formed by the two-repeat ALS- and FTD-related GGGGCC sequence.
Nucleic Acids Res., 49, 2021
7CSK
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BU of 7csk by Molmil
A 2:1 stoichiometric complex of anticancer drug Adriamycin bound to parallel G-quadruplex DNA [d-(TTGGGGT)]4.
Descriptor: DNA (5'-D(*TP*TP*GP*GP*GP*GP*T)-3'), DOXORUBICIN
Authors:Barthwal, R, Tariq, Z, Pandav, K.
Deposit date:2020-08-15
Release date:2021-08-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A 2:1 stoichiometric complex of anticancer drug Adriamycin bound to parallel G-quadruplex DNA [d-(TTGGGGT)]4.
To Be Published
8TAA
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BU of 8taa by Molmil
Right-left hybrid parallel G-quadruplex in complex with N-methyl mesoporphyrin
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (25-MER), N-METHYLMESOPORPHYRIN, ...
Authors:Seth, P.C, Yatsunyk, L.A.
Deposit date:2023-06-27
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Right-left hybrid parallel G-quadruplex in complex with N-methyl mesoporphyrin
To Be Published
6E82
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BU of 6e82 by Molmil
Crystal structure of the Corn aptamer mutant A14U in complex with ThT
Descriptor: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, POTASSIUM ION, RNA (36-MER)
Authors:Sjekloca, L, Ferre-D'Amare, A.R.
Deposit date:2018-07-27
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence.
Cell Chem Biol, 26, 2019
6E80
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BU of 6e80 by Molmil
Crystal structure of the Corn aptamer in unliganded state
Descriptor: ACETATE ION, IRIDIUM HEXAMMINE ION, IRIDIUM ION, ...
Authors:Sjekloca, L, Ferre-D'Amare, A.R.
Deposit date:2018-07-27
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence.
Cell Chem Biol, 26, 2019
6E84
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BU of 6e84 by Molmil
Crystal structure of the Corn aptamer in complex with TO
Descriptor: 1-methyl-4-[(Z)-(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]quinolin-1-ium, POTASSIUM ION, RNA (36-MER)
Authors:Sjekloca, L, Ferre-D'Amare, A.R.
Deposit date:2018-07-27
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence.
Cell Chem Biol, 26, 2019
6E81
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BU of 6e81 by Molmil
Crystal structure of the Corn aptamer in complex with ThT
Descriptor: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, POTASSIUM ION, RNA (36-MER)
Authors:Sjekloca, L, Ferre-D'Amare, A.R.
Deposit date:2018-07-27
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.721 Å)
Cite:Binding between G Quadruplexes at the Homodimer Interface of the Corn RNA Aptamer Strongly Activates Thioflavin T Fluorescence.
Cell Chem Biol, 26, 2019
7X8O
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BU of 7x8o by Molmil
NMR Solution Structure of the 2:1 Coptisine-KRAS-G4 Complex
Descriptor: 6,7-dihydro[1,3]dioxolo[4,5-g][1,3]dioxolo[7,8]isoquino[3,2-a]isoquinolin-5-ium, DNA (24-MER)
Authors:Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
Deposit date:2022-03-14
Release date:2022-09-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
7X8M
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BU of 7x8m by Molmil
NMR Solution Structure of the 2:1 Berberine-KRAS-G4 Complex
Descriptor: BERBERINE, DNA (24-MER)
Authors:Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
Deposit date:2022-03-14
Release date:2022-09-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
7X8N
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BU of 7x8n by Molmil
NMR Solution Structure of the Wild-type Bulge-containing KRAS-G4
Descriptor: DNA (24-mer)
Authors:Wang, K.B, Liu, Y, Li, J, Xiao, C, Gu, W, Li, Y, Xia, Y.Z, Yan, T, Yang, M.H, Kong, L.Y.
Deposit date:2022-03-14
Release date:2022-09-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural insight into the bulge-containing KRAS oncogene promoter G-quadruplex bound to berberine and coptisine.
Nat Commun, 13, 2022
7CPS
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BU of 7cps by Molmil
A 2:1 stoichiometric complex of anticancer drug 4'-Epiadriamycin bound to parallel G-quadruplex DNA [d-(TTGGGGT)]4.
Descriptor: 4'-EPIDOXORUBICIN, DNA (5'-D(*TP*TP*GP*GP*GP*GP*T)-3')
Authors:Barthwal, R, Tariq, Z, Pandav, K.
Deposit date:2020-08-07
Release date:2021-08-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A 2:1 stoichiometric complex of anticancer drug 4'-Epiadriamycin bound to parallel G-quadruplex DNA [d-(TTGGGGT)]4.
To Be Published
2GWE
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BU of 2gwe by Molmil
Crystal structure of D(G4T4G4) with six quadruplexes in the asymmetric unit.
Descriptor: 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Lee, M.P.H, Haider, S, Parkinson, G.N, Neidle, S.
Deposit date:2006-05-04
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of D(G4T4G4) with four and six quadruplexes in the asymmetric unit.
To be Published
6T9Q
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BU of 6t9q by Molmil
Crystal structure of the second, C-terminal repeat of the DNA-binding domain of human TImeless
Descriptor: Protein timeless homolog
Authors:Pellegrini, L, Holzer, S.
Deposit date:2019-10-28
Release date:2020-07-01
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Timeless couples G-quadruplex detection with processing by DDX11 helicase during DNA replication.
Embo J., 39, 2020
7SXI
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BU of 7sxi by Molmil
Solution Structure of Sds3 Capped Tudor Domain
Descriptor: Sin3 histone deacetylase corepressor complex component SDS3
Authors:Marcum, R.D, Radhakrishnan, I.
Deposit date:2021-11-23
Release date:2022-01-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes.
J.Biol.Chem., 298, 2022
6JJE
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BU of 6jje by Molmil
Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex (BrU)
Descriptor: COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*(BRU)P*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), POTASSIUM ION, ...
Authors:Zhang, Y.S, Wei, D.G.
Deposit date:2019-02-25
Release date:2020-02-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.378 Å)
Cite:Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex (BrU)
To Be Published
6JJG
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BU of 6jjg by Molmil
Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex
Descriptor: DNA (5'-D(*GP*GP*CP*TP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), POTASSIUM ION, SODIUM ION
Authors:Zhang, Y.S, Wei, D.G.
Deposit date:2019-02-25
Release date:2020-02-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.969 Å)
Cite:Crystal structure of a two-quartet DNA mixed-parallel/antiparallel G-quadruplex
To Be Published
6KFL
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BU of 6kfl by Molmil
Crystal structure of a two-quartet DNA G-quadruplex complexed with the porphyrin TMPyP4
Descriptor: (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, COBALT HEXAMMINE(III), DNA (5'-D(*GP*GP*CP*TP*CP*GP*GP*CP*GP*GP*CP*GP*GP*A)-3'), ...
Authors:Zhang, Y.S, Parkinson, G.N, Wei, D.G.
Deposit date:2019-07-08
Release date:2020-07-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of a two-quartet DNA G-quadruplex complexed with the porphyrin TMPyP4
To Be Published
7MKT
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BU of 7mkt by Molmil
Crystal structure of r(GU)11G-NMM complex
Descriptor: N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3')
Authors:Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E.
Deposit date:2021-04-26
Release date:2022-11-02
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:An atypical RNA quadruplex marks RNAs as vectors for gene silencing.
Nat.Struct.Mol.Biol., 29, 2022
7EAQ
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BU of 7eaq by Molmil
DNA quadruplex composed of i-motif and Z-DNA
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*CP*CP*TP*CP*GP*CP*G)-3')
Authors:Kondo, J, Igarashi, Y.
Deposit date:2021-03-08
Release date:2022-03-09
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:DNA quadruplex composed of i-motif and Z-DNA
To Be Published
2GWQ
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BU of 2gwq by Molmil
Crystal structure of D(G4T4G4) with four quadruplexes in the asymmetric unit.
Descriptor: 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Lee, M.P.H, Parkinson, G.N, Neidle, S.
Deposit date:2006-05-05
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of D(G4T4G4) with four and six quadruplexes in the asymmetric unit.
To be Published
2M53
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BU of 2m53 by Molmil
G-rich VEGF aptamer with LNA modifications
Descriptor: G-rich VEGF aptamer
Authors:Marusic, M, Veedu, R.N, Plavec, J.
Deposit date:2013-02-13
Release date:2013-08-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold.
Nucleic Acids Res., 41, 2013
2LLH
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BU of 2llh by Molmil
NMR structure of Npm1_c70
Descriptor: Nucleophosmin
Authors:Banci, L, Bertini, I, Brunori, M, Di Matteo, A, Federici, L, Gallo, A, Lo Sterzo, C, Mori, M.
Deposit date:2011-11-09
Release date:2012-06-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of Nucleophosmin DNA-binding Domain and Analysis of Its Complex with a G-quadruplex Sequence from the c-MYC Promoter.
J.Biol.Chem., 287, 2012
2MAY
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BU of 2may by Molmil
Structure of a G-quadruplex containing a single LNA modification
Descriptor: DNA_(5'-D(*TP*TP*GP*LGP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*A)-3')
Authors:Lech, C, Heddi, B, Adrian, M, Li, Z, Phan, A.T.
Deposit date:2013-07-22
Release date:2015-02-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Engineering G4: Towards effective incorporation of locked nucleic acid into G-quadruplexes
To be Published
2JSK
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BU of 2jsk by Molmil
Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, 16 G Form 1, NMR, 10 Structures
Descriptor: HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J.
Deposit date:2007-07-07
Release date:2008-07-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution.
Nucleic Acids Res., 35, 2007
2JSM
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BU of 2jsm by Molmil
MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural
Descriptor: HUMAN TELOMERE DNA
Authors:Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J.
Deposit date:2007-07-09
Release date:2008-07-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution
Nucleic Acids Res., 35, 2007

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