7CPS

A 2:1 stoichiometric complex of anticancer drug 4'-Epiadriamycin bound to parallel G-quadruplex DNA [d-(TTGGGGT)]4.

Summary for 7CPS

• Entry DOI: 10.2210/pdb7cps/pdb
• Descriptor: DNA (5'-D(*TP*TP*GP*GP*GP*GP*T)-3'), 4'-EPIDOXORUBICIN (2 entities in total)
• Functional Keywords: dna, g-quadruplex, parallel stranded g-quadruplex, 4'-epirubicin, 4'-epiadriamycin dna-drug complex
• Biological source: Tetrahymena thermophila
• Total number of polymer chains: 4
• Total formula weight: 9826.83

Authors

Barthwal, R.,Tariq, Z.,Pandav, K. (deposition date: 2020-08-07, release date: 2021-08-11, Last modification date: 2024-05-15)

• Primary citation: Barthwal, R.,Tariq, Z.,Pandav, K.; A 2:1 stoichiometric complex of anticancer drug 4'-Epiadriamycin bound to parallel G-quadruplex DNA [d-(TTGGGGT)]4.; To Be Published,

Experimental method

SOLUTION NMR