7CSK

A 2:1 stoichiometric complex of anticancer drug Adriamycin bound to parallel G-quadruplex DNA [d-(TTGGGGT)]4.

Summary for 7CSK

• Entry DOI: 10.2210/pdb7csk/pdb
• Descriptor: DNA (5'-D(*TP*TP*GP*GP*GP*GP*T)-3'), DOXORUBICIN (2 entities in total)
• Functional Keywords: dna, g-quadruplex, parallel stranded g-quadruplex, adriamycin, dna-drug complex
• Biological source: Tetrahymena thermophila
• Total number of polymer chains: 4
• Total formula weight: 9824.81

Authors

Barthwal, R.,Tariq, Z.,Pandav, K. (deposition date: 2020-08-15, release date: 2021-08-18, Last modification date: 2024-05-15)

• Primary citation: Barthwal, R.,Tariq, Z.,Pandav, K.; A 2:1 stoichiometric complex of anticancer drug Adriamycin bound to parallel G-quadruplex DNA [d-(TTGGGGT)]4.; To Be Published,

Experimental method

SOLUTION NMR