6DVK
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![BU of 6dvk by Molmil](/molmil-images/mine/6dvk) | Computationally designed mini tetraloop-tetraloop receptor by the RNAMake program - construct 6 (miniTTR 6) | Descriptor: | COBALT (II) ION, MAGNESIUM ION, RNA (95-MER) | Authors: | Eiler, D.R, Yesselman, J.D, Costantino, D.A, Das, R, Kieft, J.S. | Deposit date: | 2018-06-24 | Release date: | 2019-06-26 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Computational design of three-dimensional RNA structure and function. Nat Nanotechnol, 14, 2019
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7MN0
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![BU of 7mn0 by Molmil](/molmil-images/mine/7mn0) | |
7MKC
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![BU of 7mkc by Molmil](/molmil-images/mine/7mkc) | |
7MN2
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![BU of 7mn2 by Molmil](/molmil-images/mine/7mn2) | Rules for designing protein fold switches and their implications for the folding code | Descriptor: | Sb2 | Authors: | He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. | Deposit date: | 2021-04-30 | Release date: | 2022-05-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
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7NGE
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![BU of 7nge by Molmil](/molmil-images/mine/7nge) | Crystal structure of L-Trp/Indoleamine 2,3-dioxygenagse 1 (hIDO1) complex with the JK-loop refined in the closed conformation | Descriptor: | CHLORIDE ION, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... | Authors: | Mirgaux, M, Wouters, J. | Deposit date: | 2021-02-09 | Release date: | 2021-12-29 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Temporary Intermediates of L-Trp Along the Reaction Pathway of Human Indoleamine 2,3-Dioxygenase 1 and Identification of an Exo Site. Int J Tryptophan Res, 14, 2021
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7NFJ
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6CCT
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![BU of 6cct by Molmil](/molmil-images/mine/6cct) | Fragment of GID4 in complex with a short peptide | Descriptor: | Glucose-induced degradation protein 4 homolog, Tetrapeptide | Authors: | Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | Deposit date: | 2018-02-07 | Release date: | 2018-03-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis of GID4-mediated recognition of degrons for the Pro/N-end rule pathway. Nat. Chem. Biol., 14, 2018
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7NFM
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7NFO
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7NFP
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![BU of 7nfp by Molmil](/molmil-images/mine/7nfp) | A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17K | Descriptor: | CC-Type2-(LaId)4-I17K, GLYCEROL | Authors: | Burton, A.J, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. | Deposit date: | 2021-02-07 | Release date: | 2022-03-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
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2OTQ
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![BU of 2otq by Molmil](/molmil-images/mine/2otq) | Structure of the antimicrobial peptide cyclo(RRWFWR) bound to DPC micelles | Descriptor: | cRW3 cationic antimicrobial peptide | Authors: | Appelt, C, Wesselowski, A, Soderhall, J.A, Dathe, M, Schmieder, P. | Deposit date: | 2007-02-09 | Release date: | 2007-12-25 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structures of cyclic, antimicrobial peptides in a membrane-mimicking environment define requirements for activity. J.Pept.Sci., 14, 2007
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7NFK
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![BU of 7nfk by Molmil](/molmil-images/mine/7nfk) | An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24S. | Descriptor: | CC-Type2-(LaId)4-I24S, ISOPROPYL ALCOHOL | Authors: | Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. | Deposit date: | 2021-02-07 | Release date: | 2022-03-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
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6CU2
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6CUF
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![BU of 6cuf by Molmil](/molmil-images/mine/6cuf) | Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody vFP1.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Acharya, P, Carragher, B, Potter, C.S, Kwong, P.D. | Deposit date: | 2018-03-26 | Release date: | 2018-07-25 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV. PLoS Pathog., 14, 2018
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6CL2
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2N10
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6FER
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![BU of 6fer by Molmil](/molmil-images/mine/6fer) | Crystal Structure of human DDR2 kinase in complex with 2-[4,5-difluoro-2-oxo-1'-(1H-pyrazolo[3,4-b]pyridine-5-carbonyl)spiro[indole-3,4'-piperidine]-1-yl]-N-(2,2,2-trifluoroethyl)acetamide | Descriptor: | 2-[4,5-bis(fluoranyl)-2-oxidanylidene-1'-(1~{H}-pyrazolo[3,4-b]pyridin-5-ylcarbonyl)spiro[indole-3,4'-piperidine]-1-yl]-~{N}-[2,2,2-tris(fluoranyl)ethyl]ethanamide, Discoidin domain-containing receptor 2 | Authors: | Stihle, M, Richter, H, Benz, J, Kuhn, B, Rudolph, M.G. | Deposit date: | 2018-01-03 | Release date: | 2018-11-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome. Acs Chem.Biol., 14, 2019
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7NFG
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![BU of 7nfg by Molmil](/molmil-images/mine/7nfg) | A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L14A. | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CC-Type2-(LaId)4-L14A | Authors: | Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. | Deposit date: | 2021-02-07 | Release date: | 2022-03-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
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7NFH
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![BU of 7nfh by Molmil](/molmil-images/mine/7nfh) | A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(MaId)4. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CC-Type2-(MaId)4 | Authors: | Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. | Deposit date: | 2021-02-07 | Release date: | 2022-03-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
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7NFN
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![BU of 7nfn by Molmil](/molmil-images/mine/7nfn) | A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L21N-I24N. | Descriptor: | CC-Type2-(LaId)4-L21N-I24N, HEXANE-1,6-DIOL | Authors: | Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. | Deposit date: | 2021-02-07 | Release date: | 2022-03-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
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2OT3
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6EY8
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![BU of 6ey8 by Molmil](/molmil-images/mine/6ey8) | Estimation of relative drug-target residence times by random acceleration molecular dynamics simulation | Descriptor: | DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha, SULFATE ION, ... | Authors: | Musil, D, Lehmann, M, Buchstaller, H.-P. | Deposit date: | 2017-11-11 | Release date: | 2018-05-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Estimation of Drug-Target Residence Times by tau-Random Acceleration Molecular Dynamics Simulations. J Chem Theory Comput, 14, 2018
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2PEH
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![BU of 2peh by Molmil](/molmil-images/mine/2peh) | Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 | Descriptor: | Splicing factor 3B subunit 1, Splicing factor 45 | Authors: | Corsini, L, Basquin, J, Hothorn, M, Sattler, M. | Deposit date: | 2007-04-03 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat.Struct.Mol.Biol., 14, 2007
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2P4E
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![BU of 2p4e by Molmil](/molmil-images/mine/2p4e) | Crystal Structure of PCSK9 | Descriptor: | MERCURY (II) ION, Proprotein convertase subtilisin/kexin type 9 | Authors: | Cunningham, D, Danley, D.E, Geoghegan, F.K, Griffor, M.C, Hawkins, J.L, Qiu, X. | Deposit date: | 2007-03-12 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia. Nat.Struct.Mol.Biol., 14, 2007
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6ESP
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![BU of 6esp by Molmil](/molmil-images/mine/6esp) | |