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8EOW
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BU of 8eow by Molmil
Eag Kv channel with voltage sensor in the up conformation
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Mandala, V.S, MacKinnon, R.
Deposit date:2022-10-04
Release date:2022-11-16
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
6I9D
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BU of 6i9d by Molmil
MloK1 consensus structure from single particle analysis of 2D crystals
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-11-23
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6PBX
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BU of 6pbx by Molmil
Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 2)
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Whicher, J.R, MacKinnon, R.
Deposit date:2019-06-14
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Regulation of Eag1 gating by its intracellular domains.
Elife, 8, 2019
5VA3
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BU of 5va3 by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Wang, W.W, MacKinnon, R.
Deposit date:2017-03-24
Release date:2017-05-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG.
Cell, 169, 2017
2ZD9
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BU of 2zd9 by Molmil
Structure of a Bacterial Cyclic-Nucleotide Regulated Ion Channel
Descriptor: Mll3241 protein, POTASSIUM ION
Authors:Clayton, G.M, Cabral-Morais, J.M.
Deposit date:2007-11-21
Release date:2008-12-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structure of the transmembrane regions of a bacterial cyclic nucleotide-regulated channel.
Proc.Natl.Acad.Sci.USA, 105, 2008
7LZ4
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BU of 7lz4 by Molmil
Crystal structure of A211D mutant of Protein Kinase A RIa subunit, a Carney Complex mutation
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed
Authors:Del Rio, J, Wu, J, Taylor, S.S.
Deposit date:2021-03-08
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.155 Å)
Cite:Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations.
Proc.Natl.Acad.Sci.USA, 118, 2021
5V4S
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BU of 5v4s by Molmil
CryoEM Structure of a Prokaryotic Cyclic Nucleotide-Gated Ion Channel
Descriptor: Transporter, cation channel family / cyclic nucleotide-binding domain multi-domain protein
Authors:James, Z.M, Borst, A.J, Haitin, Y, Frenz, B, DiMaio, F, Zagotta, W.N, Veesler, D.
Deposit date:2017-03-10
Release date:2017-04-12
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6PB6
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BU of 6pb6 by Molmil
The E. coli class-II CAP-dependent transcription activation complex at the state 2
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W.
Deposit date:2019-06-13
Release date:2020-03-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.29 Å)
Cite:Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
7RU0
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BU of 7ru0 by Molmil
SthK R120A Open State 1
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SthK
Authors:Gao, X, Nimigean, C, Schmidpeter, P.
Deposit date:2021-08-16
Release date:2022-11-23
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Gating intermediates reveal inhibitory role of the voltage sensor in a cyclic nucleotide-modulated ion channel.
Nat Commun, 13, 2022
6PB4
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BU of 6pb4 by Molmil
The E. coli class-II CAP-dependent transcription activation complex with de novo RNA transcript at the state 2
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W.
Deposit date:2019-06-13
Release date:2020-03-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.35 Å)
Cite:Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
6QCZ
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BU of 6qcz by Molmil
MloK1 model from single particle analysis of 2D crystals, class 3 (intermediate extended conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
5I2D
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BU of 5i2d by Molmil
Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo
Descriptor: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Feng, Y, Zhang, Y, Ebright, R.H.
Deposit date:2016-02-08
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (4.405 Å)
Cite:Structural basis of transcription activation.
Science, 352, 2016
6EO1
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BU of 6eo1 by Molmil
The electron crystallography structure of the cAMP-bound potassium channel MloK1 (PCO-refined)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Kowal, J, Biyani, N, Chami, M, Scherer, S, Rzepiela, A, Baumgartner, P, Upadhyay, V, Nimigean, C, Stahlberg, H.
Deposit date:2017-10-08
Release date:2017-12-27
Last modified:2024-05-15
Method:ELECTRON CRYSTALLOGRAPHY (4.5 Å)
Cite:High-Resolution Cryoelectron Microscopy Structure of the Cyclic Nucleotide-Modulated Potassium Channel MloK1 in a Lipid Bilayer.
Structure, 26, 2018
6QD0
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BU of 6qd0 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 4 (compact/open conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
8H3V
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BU of 8h3v by Molmil
Cryo-EM structure of the full transcription activation complex NtcA-NtcB-TAC
Descriptor: DNA (125-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Han, S.J, Jiang, Y.L, You, L.L, Shen, L.Q, Wu, X.X, Yang, F, Kong, W.W, Chen, Z.P, Zhang, Y, Zhou, C.Z.
Deposit date:2022-10-09
Release date:2023-10-04
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:DNA looping mediates cooperative transcription activation.
Nat.Struct.Mol.Biol., 31, 2024
6PB5
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BU of 6pb5 by Molmil
The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Liu, B, Shi, W.
Deposit date:2019-06-13
Release date:2020-03-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.52 Å)
Cite:Visualization of two architectures in class-II CAP-dependent transcription activation
Plos Biol., 18, 2020
6QCY
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BU of 6qcy by Molmil
MloK1 model from single particle analysis of 2D crystals, class 2 (intermediate conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
6BYS
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BU of 6bys by Molmil
Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PRKAc alpha
Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit
Authors:Cao, B, Lu, T.W, Martinez Fiesco, J.A, Tomasini, M, Fan, L, Simon, S.M, Taylor, S.S, Zhang, P.
Deposit date:2017-12-21
Release date:2019-04-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (4.75 Å)
Cite:Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha.
Structure, 27, 2019
6QD2
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BU of 6qd2 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 6 (intermediate compact conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
8EP0
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BU of 8ep0 by Molmil
Eag Kv channel with voltage sensor in the intermediate conformation
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Mandala, V.S, MacKinnon, R.
Deposit date:2022-10-04
Release date:2022-11-16
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
6QD3
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BU of 6qd3 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 7 (intermediate conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
5CIZ
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BU of 5ciz by Molmil
E. coli RNA polymerase alpha subunit CTD in complex with CAP and DNA: A(5)-tract binding site for alpha CTD
Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, DNA (5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*AP*GP*GP*CP*AP*AP*AP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*TP*TP*TP*GP*CP*CP*TP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3'), ...
Authors:Napoli, A.A, Lawson, C.L.
Deposit date:2015-07-13
Release date:2016-06-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (5.0098 Å)
Cite:The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element
Biochemistry, 2020
6IAX
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BU of 6iax by Molmil
MloK1 model from single particle analysis of 2D crystals, class 1 (extended conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-11-27
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
8EP1
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BU of 8ep1 by Molmil
Eag Kv channel with voltage sensor in the down conformation
Descriptor: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
Authors:Mandala, V.S, MacKinnon, R.
Deposit date:2022-10-04
Release date:2022-11-16
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
6QD1
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BU of 6qd1 by Molmil
MloK1 model from single particle analysis of 2D crystals, class 5 (intermediate compact conformation)
Descriptor: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
Authors:Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
Deposit date:2018-12-31
Release date:2019-04-24
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019

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