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3Q4J
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BU of 3q4j by Molmil
Structure of a small peptide ligand bound to E.coli DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, peptide ligand
Authors:Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D.
Deposit date:2010-12-23
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J.Med.Chem., 54, 2011
3Q4K
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BU of 3q4k by Molmil
Structure of a small peptide ligand bound to E.coli DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, peptide ligand
Authors:Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D.
Deposit date:2010-12-23
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J.Med.Chem., 54, 2011
3Q4L
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BU of 3q4l by Molmil
Structure of a small peptide ligand bound to E.coli DNA sliding clamp
Descriptor: DNA polymerase III subunit beta, SODIUM ION, peptide ligand
Authors:Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D.
Deposit date:2010-12-23
Release date:2011-12-28
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure-based design of short peptide ligands binding onto the E. coli processivity ring.
J.Med.Chem., 54, 2011
1YYP
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BU of 1yyp by Molmil
Crystal structure of cytomegalovirus UL44 bound to C-terminal peptide from CMV UL54
Descriptor: 1,2-ETHANEDIOL, DNA polymerase, DNA polymerase processivity factor, ...
Authors:Appleton, B.A, Brooks, J, Loregian, A, Filman, D.J, Coen, D.M, Hogle, J.M.
Deposit date:2005-02-25
Release date:2005-12-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44.
J.Biol.Chem., 281, 2006
7TFI
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BU of 7tfi by Molmil
Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with an open clamp
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2022-01-06
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
7TFJ
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BU of 7tfj by Molmil
Atomic model of S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to DNA with a closed clamp ring
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2022-01-06
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
5AGU
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BU of 5agu by Molmil
The sliding clamp of Mycobacterium tuberculosis in complex with a natural product.
Descriptor: (R,R)-2,3-BUTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA POLYMERASE III SUBUNIT BETA, ...
Authors:Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
Deposit date:2015-02-03
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.173 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
5AGV
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BU of 5agv by Molmil
The sliding clamp of Mycobacterium tuberculosis in complex with a natural product.
Descriptor: (R,R)-2,3-BUTANEDIOL, CALCIUM ION, CYCLOHEXYL GRISELIMYCIN, ...
Authors:Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
Deposit date:2015-02-03
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
4RJF
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BU of 4rjf by Molmil
Crystal structure of the human sliding clamp at 2.0 angstrom resolution
Descriptor: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
Authors:Kroker, A.J, Bruning, J.B.
Deposit date:2014-10-09
Release date:2015-08-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.0072 Å)
Cite:p21 Exploits Residue Tyr151 as a Tether for High-Affinity PCNA Binding.
Biochemistry, 54, 2015
6EHT
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BU of 6eht by Molmil
Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme
Descriptor: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ...
Authors:De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
Deposit date:2017-09-15
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
8RBO
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BU of 8rbo by Molmil
Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation
Descriptor: DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ...
Authors:Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D.
Deposit date:2023-12-04
Release date:2024-04-24
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment.
Nucleic Acids Res., 52, 2024
7TFH
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BU of 7tfh by Molmil
Atomic model of the S. cerevisiae clamp-clamp loader complex PCNA-RFC bound to two DNA molecules, one at the 5'-recessed end and the other at the 3'-recessed end
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
Authors:Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H.
Deposit date:2022-01-06
Release date:2022-11-16
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Cryo-EM structures reveal that RFC recognizes both the 3'- and 5'-DNA ends to load PCNA onto gaps for DNA repair.
Elife, 11, 2022
5KL1
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BU of 5kl1 by Molmil
Crystal structure of the Pumilio-Nos-hunchback RNA complex
Descriptor: Maternal protein pumilio, Protein nanos, RNA (5'-R(*AP*AP*AP*UP*UP*GP*UP*AP*CP*AP*UP*A)-3'), ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2016-06-23
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.701 Å)
Cite:Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
5KL8
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BU of 5kl8 by Molmil
Crystal structure of the Pumilio-Nos-CyclinB RNA complex
Descriptor: Maternal protein pumilio, Protein nanos, RNA (5'-R(*UP*AP*UP*UP*UP*GP*UP*AP*AP*UP*U)-3'), ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2016-06-23
Release date:2016-08-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
5KLA
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BU of 5kla by Molmil
Crystal structure of the drosophila Pumilio RNA-binding domain in complex with hunchback RNA
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, Maternal protein pumilio, ...
Authors:Qiu, C, Hall, T.M.T.
Deposit date:2016-06-23
Release date:2016-08-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.
Elife, 5, 2016
6C04
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BU of 6c04 by Molmil
Mtb RNAP Holo/RbpA/double fork DNA -closed clamp
Descriptor: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J, Lilic, M.
Deposit date:2017-12-27
Release date:2018-03-28
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
2V5Y
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BU of 2v5y by Molmil
Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, SODIUM ION
Authors:Aricescu, A.R, Siebold, C, Choudhuri, K, Chang, V.T, Lu, W, Davis, S.J, van der Merwe, P.A, Jones, E.Y.
Deposit date:2007-07-11
Release date:2007-09-11
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a Tyrosine Phosphatase Adhesive Interaction Reveals a Spacer-Clamp Mechanism.
Science, 317, 2007
8UI7
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BU of 8ui7 by Molmil
Cryo-EM map of human clmap-clamp loader ATAD5-RFC-gapped PCNA complex in intermediate state 3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ...
Authors:Wang, F, He, Q, Li, H.
Deposit date:2023-10-10
Release date:2024-05-29
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader.
Nat.Struct.Mol.Biol., 2024
3A1J
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BU of 3a1j by Molmil
Crystal structure of the human Rad9-Hus1-Rad1 complex
Descriptor: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Checkpoint protein HUS1, ...
Authors:Sohn, S.Y, Cho, Y.
Deposit date:2009-04-08
Release date:2009-06-02
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Human Rad9-Hus1-Rad1 Clamp
J.Mol.Biol., 390, 2009
5AH2
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BU of 5ah2 by Molmil
The sliding clamp of Mycobacterium smegmatis in complex with a natural product.
Descriptor: DNA POLYMERASE III SUBUNIT BETA, GRISELIMYCIN, SODIUM ION
Authors:Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
Deposit date:2015-02-04
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.129 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
5AH4
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BU of 5ah4 by Molmil
The sliding clamp of Mycobacterium smegmatis in complex with a natural product.
Descriptor: CYCLOHEXYL GRISELIMYCIN, DNA POLYMERASE III SUBUNIT BETA, SODIUM ION
Authors:Lukat, P, Kling, A, Heinz, D.W, Mueller, R.
Deposit date:2015-02-04
Release date:2015-06-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.313 Å)
Cite:Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins.
Science, 348, 2015
7AIB
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BU of 7aib by Molmil
MutS-MutL in clamp state
Descriptor: DNA (30-MER), DNA mismatch repair protein MutL, DNA mismatch repair protein MutS, ...
Authors:Fernandez-Leiro, R, Bhairosing-Kok, D, Sixma, T.K, Lamers, M.H.
Deposit date:2020-09-26
Release date:2021-03-31
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:The selection process of licensing a DNA mismatch for repair.
Nat.Struct.Mol.Biol., 28, 2021
7FIL
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BU of 7fil by Molmil
The cryo-EM structure of the NTD2 from the X. laevis Nup358
Descriptor: Nup358 complex, clamps
Authors:Shi, Y, Zhan, X, Huang, G.
Deposit date:2021-07-31
Release date:2022-06-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex.
Science, 376, 2022
7FIK
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BU of 7fik by Molmil
The cryo-EM structure of the CR subunit from X. laevis NPC
Descriptor: MGC154553 protein, MGC83295 protein, MGC83926 protein, ...
Authors:Shi, Y, Huang, G, Zhan, X.
Deposit date:2021-07-31
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex.
Science, 376, 2022
8THB
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BU of 8thb by Molmil
Structure of the Saccharomyces cerevisiae PCNA clamp unloader Elg1-RFC complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ELG1 isoform 1, MAGNESIUM ION, ...
Authors:Zheng, F, Yao, Y.N, Georgescu, R, O'Donnell, M.E, Li, H.
Deposit date:2023-07-14
Release date:2024-05-22
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the PCNA unloader Elg1-RFC.
Sci Adv, 10, 2024

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PDB entries from 2024-08-07

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