2KJL
| |
8QTY
| |
2KI9
| Human cannabinoid receptor-2 helix 6 | Descriptor: | Cannabinoid receptor 2 | Authors: | Deshmukh, L, Vinogradova, O, Tiburu, E.K, Tyukhtenko, S, Janero, D.R, Makriyannis, A. | Deposit date: | 2009-04-28 | Release date: | 2009-05-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural biology of human cannabinoid receptor-2 helix 6 in membrane-mimetic environments. Biochem.Biophys.Res.Commun., 384, 2009
|
|
7S13
| Crystal structure of Fab in complex with mouse CD96 dimer | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRATE ANION, ... | Authors: | Lee, P.S, Barman, I, Strop, P. | Deposit date: | 2021-08-31 | Release date: | 2021-10-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Antibody blockade of CD96 by distinct molecular mechanisms. Mabs, 13, 2021
|
|
3KCK
| A Novel Chemotype of Kinase Inhibitors | Descriptor: | 3-chloro-4-(4H-3,4,7-triazadibenzo[cd,f]azulen-6-yl)phenol, Tyrosine-protein kinase JAK2 | Authors: | Zuccola, H.J, Wang, T, Ledeboer, M.W. | Deposit date: | 2009-10-21 | Release date: | 2009-11-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
|
|
7S11
| Crystal structure of Fab in complex with mouse CD96 monomer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | Authors: | Lee, P.S, Chau, B, Strop, P. | Deposit date: | 2021-08-31 | Release date: | 2021-11-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Antibody blockade of CD96 by distinct molecular mechanisms. Mabs, 13, 2021
|
|
6W2Y
| CryoEM Structure of GABAB1b Homodimer | Descriptor: | (1S)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Papasergi-Scott, M.M, Robertson, M.J, Skiniotis, G. | Deposit date: | 2020-03-08 | Release date: | 2020-07-01 | Last modified: | 2020-08-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of metabotropic GABABreceptor. Nature, 584, 2020
|
|
3KM5
| Crystal Structure Analysis of the K2 Cleaved Adhesin Domain of Lys-gingipain (Kgp) | Descriptor: | CALCIUM ION, GLYCEROL, Lysine specific cysteine protease, ... | Authors: | Li, N, Collyer, C.A, Hunter, N. | Deposit date: | 2009-11-09 | Release date: | 2010-03-31 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure determination and analysis of a haemolytic gingipain adhesin domain from Porphyromonas gingivalis Mol.Microbiol., 76, 2010
|
|
3KMG
| |
6W3N
| APE1 exonuclease substrate complex D148E | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(C7R))-3'), ... | Authors: | Freudenthal, B.D, Whitaker, A.M. | Deposit date: | 2020-03-09 | Release date: | 2020-06-10 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
|
|
3KVQ
| |
6PNP
| Crystal structure of the splice insert-free neurexin-1 LNS2 domain in complex with neurexophilin-1 | Descriptor: | Neurexin-1, Neurexophilin-1 | Authors: | Wilson, S.C, White, K.I, Zhou, Q, Brunger, A.T. | Deposit date: | 2019-07-02 | Release date: | 2019-10-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing. Embo J., 38, 2019
|
|
7S2S
| nanobody bound to Interleukin-2Rbeta | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IL2Rb-binding nanobody, Interleukin-2 receptor subunit beta, ... | Authors: | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | Deposit date: | 2021-09-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Facile discovery of surrogate cytokine agonists. Cell, 185, 2022
|
|
7S2R
| nanobody bound to IL-2Rg | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... | Authors: | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | Deposit date: | 2021-09-03 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Facile discovery of surrogate cytokine agonists. Cell, 185, 2022
|
|
2L68
| Solution Structure of Human Holo L-FABP | Descriptor: | Fatty acid-binding protein, liver | Authors: | Cai, J, Luecke, C, Chen, Z, Qiao, Y, Klimtchuk, E.S, Hamilton, J.A. | Deposit date: | 2010-11-17 | Release date: | 2011-11-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of human liver fatty acid binding protein: fatty acid binding revisited. Biophys.J., 102, 2012
|
|
7S8V
| |
7S0Q
| |
2L67
| Solution Structure of Human Apo L-FABP | Descriptor: | Fatty acid-binding protein, liver | Authors: | Cai, J, Luecke, C, Chen, Z, Qiao, Y, Klimtchuk, E.S, Hamilton, J.A. | Deposit date: | 2010-11-17 | Release date: | 2011-11-23 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of human liver fatty acid binding protein: fatty acid binding revisited. Biophys.J., 102, 2012
|
|
4DDR
| Human dihydrofolate reductase complexed with NADPH and P218 | Descriptor: | 3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Yuthavong, Y, Tarnchompoo, B, Vilaivan, T, Chitnumsub, P, Kamchonwongpaisan, S, Charman, S.A, McLennan, D.N, White, K.L, Vivas, L, Bongard, E, Thongphanchang, C, Taweechai, S, Vanichtanankul, J, Rattanajak, R, Arwon, U, Fantauzzi, P, Yuvaniyama, J, Charman, W.N, Matthews, D. | Deposit date: | 2012-01-19 | Release date: | 2012-11-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
6WGO
| The interaction of dichlorido(3-(anthracen-9-ylmethyl)-1-methylimidazol-2-ylidene)(eta6-p-cymene)ruthenium(II) with HEWL after 1 week | Descriptor: | ACETATE ION, Lysozyme, SODIUM ION, ... | Authors: | Sullivan, M.P, Hartinger, C.G, Goldstone, D.C. | Deposit date: | 2020-04-06 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Anthracenyl Functionalization of Half-Sandwich Carbene Complexes: In Vitro Anticancer Activity and Reactions with Biomolecules. Inorg.Chem., 60, 2021
|
|
8U1W
| Structure of Norovirus (Hu/GII.4/Sydney/NSW0514/2012/AU) protease bound to inhibitor NV-004 | Descriptor: | ACETATE ION, GLYCEROL, Peptidase C37, ... | Authors: | Eruera, A.R, Campbell, A.C, Krause, K.L. | Deposit date: | 2023-09-03 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Crystal Structure of Inhibitor-Bound GII.4 Sydney 2012 Norovirus 3C-Like Protease. Viruses, 15, 2023
|
|
3N9J
| |
6XA1
| |
1TOQ
| CRYSTAL STRUCTURE OF A GALACTOSE SPECIFIC LECTIN FROM ARTOCARPUS HIRSUTA IN COMPLEX WITH METHYL-a-D-GALACTOSE | Descriptor: | AGGLUTININ ALPHA CHAIN, AGGLUTININ BETA CHAIN, methyl alpha-D-galactopyranoside | Authors: | Rao, K.N, Suresh, C.G, Katre, U.V, Gaikwad, S.M, Khan, M.I. | Deposit date: | 2004-06-15 | Release date: | 2004-08-03 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Two orthorhombic crystal structures of a galactose-specific lectin from Artocarpus hirsuta in complex with methyl-alpha-D-galactose. Acta Crystallogr.,Sect.D, 60, 2004
|
|
6MES
| |