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8OJT
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BU of 8ojt by Molmil
Crystal structure of the human IgD Fab - structure Fab2
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AZIDE ION, ...
Authors:Davies, A.M, Beavil, R.L, McDonnell, J.M.
Deposit date:2023-03-24
Release date:2023-06-14
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Mol.Immunol., 159, 2023
5E7K
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BU of 5e7k by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA and cognate tRNALys in the A-site
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G.
Deposit date:2015-10-12
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
1CLY
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BU of 1cly by Molmil
IGG FAB (HUMAN IGG1, KAPPA) CHIMERIC FRAGMENT (CBR96) COMPLEXED WITH LEWIS Y NONOATE METHYL ESTER
Descriptor: IGG FAB (HUMAN IGG1, KAPPA), METHYL NONANOATE (ESTER), ...
Authors:Sheriff, S, Bajorath, J.
Deposit date:1995-03-15
Release date:1996-08-01
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The x-ray structure of an anti-tumour antibody in complex with antigen.
Nat.Struct.Biol., 2, 1995
3M37
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BU of 3m37 by Molmil
Factor XA in complex with the inhibitor 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC602)
Descriptor: 1-[2-(aminomethyl)phenyl]-N-(3-fluoro-2'-sulfamoylbiphenyl-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide, CALCIUM ION, Coagulation factor X
Authors:Alexander, R.S.
Deposit date:2010-03-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of 1-(2-Aminomethylphenyl)-3-trifluoromethyl-N-[3-fluoro-2'-(aminosulfonyl)[1,1'-biphenyl)]-1H-pyrazole-5-carboxyamide (DPC602), a Potent, Selective, and Orally Bioavailable Factor Xa Inhibitor.
J.Med.Chem., 46, 2003
3M4N
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BU of 3m4n by Molmil
Crystal structure of N-acetyl-L-ornithine transcarbamylase K302A mutant complexed with PALAO
Descriptor: N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION
Authors:Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D.
Deposit date:2010-03-11
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase.
Biochemistry, 49, 2010
5DOY
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BU of 5doy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
Authors:Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
Deposit date:2015-09-11
Release date:2015-12-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
8GUY
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BU of 8guy by Molmil
human insulin receptor bound with two insulin molecules
Descriptor: Insulin A chain, Insulin, isoform 2, ...
Authors:Kim, J, Yunn, N, Ryu, S, Cho, Y.
Deposit date:2022-09-14
Release date:2022-11-09
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.18 Å)
Cite:Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures.
Nat Commun, 13, 2022
5EL6
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BU of 5el6 by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position and antibiotic paromomycin
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G.
Deposit date:2015-11-04
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
3M5C
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BU of 3m5c by Molmil
Crystal structure of N-acetyl-L-ornithine transcarbamylase K302E mutant complexed with PALAO
Descriptor: N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION
Authors:Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D.
Deposit date:2010-03-12
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase.
Biochemistry, 49, 2010
5EL4
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BU of 5el4 by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the first position
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G.
Deposit date:2015-11-04
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5EL7
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BU of 5el7 by Molmil
Structure of T. thermophilus 70S ribosome complex with mRNA and tRNALys in the A-site with a U-U mismatch in the second position and antibiotic paromomycin
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G.
Deposit date:2015-11-04
Release date:2016-01-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code.
Nat Commun, 7, 2016
5DAT
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BU of 5dat by Molmil
Complex of yeast 80S ribosome with hypusine-containing eIF5A
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
Deposit date:2015-08-20
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
8OM9
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BU of 8om9 by Molmil
MutSbeta bound to (CAG)2 DNA (open form)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ...
Authors:Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C.
Deposit date:2023-03-31
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:MutSbeta bound to (CAG)2 DNA (open form)
To Be Published
8ZGT
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BU of 8zgt by Molmil
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Du, S, Deng, M.J, Xiao, J.Y.
Deposit date:2024-05-09
Release date:2024-07-10
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 2024
8OLX
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BU of 8olx by Molmil
MutSbeta bound to (CAG)2 DNA (canonical form)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (25-MER), DNA mismatch repair protein Msh2, ...
Authors:Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C.
Deposit date:2023-03-30
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:MutSbeta bound to (CAG)2 DNA (canonical form)
To Be Published
8OMO
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BU of 8omo by Molmil
DNA-unbound MutSbeta-ATP complex (bent clamp form)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ...
Authors:Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C.
Deposit date:2023-03-31
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:DNA-unbound MutSbeta-ATP complex (bent clamp form)
To Be Published
8OM5
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BU of 8om5 by Molmil
DNA-free open form of MutSbeta
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ...
Authors:Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C.
Deposit date:2023-03-31
Release date:2023-05-24
Method:ELECTRON MICROSCOPY (3.52 Å)
Cite:DNA-free open form of MutSbeta
To Be Published
8OMA
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BU of 8oma by Molmil
MutSbeta bound to 61bp homoduplex DNA
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ...
Authors:Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C.
Deposit date:2023-03-31
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:MutSbeta bound to 61bp homoduplex DNA
To Be Published
8OMQ
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BU of 8omq by Molmil
DNA-unbound MutSbeta-ATP complex (straight clamp form)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA mismatch repair protein Msh2, DNA mismatch repair protein Msh3, ...
Authors:Lee, J.-H, Thomsen, M, Daub, H, Steinbacher, S, Sztyler, A, Thieulin-Pardo, G, Neudegger, T, Plotnikov, N, Iyer, R.R, Wilkinson, H, Monteagudo, E, Felsenfeld, D.P, Haque, T, Finley, M, Dominguez, C, Vogt, T.F, Prasad, B.C.
Deposit date:2023-03-31
Release date:2023-05-24
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:DNA-unbound MutSbeta-ATP complex (straight clamp form)
To Be Published
8Y81
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BU of 8y81 by Molmil
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
Authors:Du, S, Deng, M.J, Xiao, J.Y.
Deposit date:2024-02-05
Release date:2024-07-10
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Structural insights into the high-affinity IgE receptor Fc epsilon RI complex.
Nature, 2024
8OJS
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BU of 8ojs by Molmil
Crystal structure of the human IgD Fab - structure Fab1
Descriptor: 1,2-ETHANEDIOL, Human IgD Fab heavy chain, Human IgD Fab light chain, ...
Authors:Davies, A.M, Beavil, R.L, McDonnell, J.M.
Deposit date:2023-03-24
Release date:2023-06-14
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Mol.Immunol., 159, 2023
8OJU
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BU of 8oju by Molmil
Crystal structure of the human IgD Fab - structure Fab3
Descriptor: 1,2-ETHANEDIOL, Human IgD Fab heavy chain, Human IgD Fab light chain, ...
Authors:Davies, A.M, Beavil, R.L, McDonnell, J.M.
Deposit date:2023-03-24
Release date:2023-06-14
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Mol.Immunol., 159, 2023
8OJV
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BU of 8ojv by Molmil
Crystal structure of the human IgD Fab - structure Fab4
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Davies, A.M, Beavil, R.L, McDonnell, J.M.
Deposit date:2023-03-24
Release date:2023-06-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the human IgD Fab reveal insights into C H 1 domain diversity.
Mol.Immunol., 159, 2023
5BWJ
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BU of 5bwj by Molmil
Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor
Descriptor: MAGNESIUM ION, NITRATE ION, Sensory transduction histidine kinase, ...
Authors:Bauer, W.J, Luthra, A, Zhu, G, Radolf, J.D, Malkowski, M.G, Caimano, M.J.
Deposit date:2015-06-08
Release date:2015-07-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding.
J.Struct.Biol., 192, 2015
6VBP
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BU of 6vbp by Molmil
Crystal structure of anti-HIV-1 antibody DH815 bound to gp120 V2 peptide
Descriptor: CHLORIDE ION, DH815 heavy chain, DH815 light chain, ...
Authors:Janus, B.M, Ofek, G.
Deposit date:2019-12-19
Release date:2020-02-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.
JCI Insight, 5, 2020

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PDB entries from 2024-09-18

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