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8XRY
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BU of 8xry by Molmil
Cryo-EM structure of OSCA3.1-1.1ver(Y367N-G454S-Y458I)-open/open state
Descriptor: CSC1-like protein ERD4
Authors:Zhang, Y, Han, Y.
Deposit date:2024-01-08
Release date:2024-04-10
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XRU
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BU of 8xru by Molmil
The crystal structure of a GH3 enzyme CcBgl3B with glycerol
Descriptor: CALCIUM ION, GH3 enzyme CcBgl3B, GLYCEROL
Authors:Su, J.Y.
Deposit date:2024-01-08
Release date:2024-04-10
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:A trapped covalent intermediate as a key catalytic element in the hydrolysis of a GH3 beta-glucosidase: An X-ray crystallographic and biochemical study.
Int.J.Biol.Macromol., 265, 2024
8XR3
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BU of 8xr3 by Molmil
Crystal structure of AKRtyl-apo2
Descriptor: Aldo/keto reductase
Authors:Lin, S, Dai, S, Xiao, Z.
Deposit date:2024-01-06
Release date:2024-04-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D.
Nat Commun, 15, 2024
8XQB
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BU of 8xqb by Molmil
Mature virion portal vertex of bacteriophage lambda
Descriptor: Capsid decoration protein, Head completion protein, Head-tail connector protein FII, ...
Authors:Wang, J.W, Gu, Z.W.
Deposit date:2024-01-05
Release date:2024-04-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (4.07 Å)
Cite:Structural morphing in the viral portal vertex of bacteriophage lambda.
J.Virol., 98, 2024
8XPV
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BU of 8xpv by Molmil
The Crystal Structure of EphA2 from Biortus.
Descriptor: 1,2-ETHANEDIOL, 1-(3,3-dimethylbutyl)-3-{2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl}urea, Ephrin type-A receptor 2, ...
Authors:Wang, F, Cheng, W, Lv, Z, Meng, Q, Xu, Y.
Deposit date:2024-01-04
Release date:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The Crystal Structure of EphA2 from Biortus.
To Be Published
8XPN
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BU of 8xpn by Molmil
The Crystal Structure of USP8 from Biortus.
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ubiquitin carboxyl-terminal hydrolase 8, ...
Authors:Wang, F, Cheng, W, Yuan, Z, Lin, D, Wang, J.
Deposit date:2024-01-04
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Crystal Structure of USP8 from Biortus.
To Be Published
8XPM
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BU of 8xpm by Molmil
Mature virion portal of phage lambda with DNA
Descriptor: DNA (104-MER), DNA (92-MER), Head completion protein, ...
Authors:Wang, J.W, Gu, Z.W.
Deposit date:2024-01-04
Release date:2024-04-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural morphing in the viral portal vertex of bacteriophage lambda.
J.Virol., 98, 2024
8XPE
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BU of 8xpe by Molmil
Crystal structure of Tris-bound TsaBgl (DATA III)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, beta-glucosidase
Authors:Nam, K.H.
Deposit date:2024-01-03
Release date:2024-01-31
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural analysis of Tris binding in beta-glucosidases.
Biochem.Biophys.Res.Commun., 700, 2024
8XPD
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BU of 8xpd by Molmil
Crystal structure of Tris-bound TsaBgl (DATA II)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, beta-glucosidase
Authors:Nam, K.H.
Deposit date:2024-01-03
Release date:2024-01-31
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural analysis of Tris binding in beta-glucosidases.
Biochem.Biophys.Res.Commun., 700, 2024
8XPC
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BU of 8xpc by Molmil
Crystal structure of Tris-bound TsaBgl (DATA I)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, beta-glucosidase
Authors:Nam, K.H.
Deposit date:2024-01-03
Release date:2024-01-31
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural analysis of Tris binding in beta-glucosidases.
Biochem.Biophys.Res.Commun., 700, 2024
8XP5
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BU of 8xp5 by Molmil
The Crystal Structure of p53/BCL-xL fusion complex from Biortus.
Descriptor: Bcl-2-like protein 1,Cellular tumor antigen p53, ZINC ION
Authors:Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C.
Deposit date:2024-01-03
Release date:2024-03-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The Crystal Structure of p53/BCL-xL fusion complex from Biortus.
To Be Published
8XOY
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BU of 8xoy by Molmil
The Crystal Structure of PTP1B from Biortus.
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Wang, F, Cheng, W, Lv, Z, Meng, Q, Li, J.
Deposit date:2024-01-02
Release date:2024-01-24
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The Crystal Structure of PTP1B from Biortus.
To Be Published
8XOW
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BU of 8xow by Molmil
Mature virion portal of bacteriophage lambda
Descriptor: Head completion protein, Head-tail connector protein FII, Portal protein B, ...
Authors:Wang, J.W, Gu, Z.W.
Deposit date:2024-01-02
Release date:2024-04-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Structural morphing in the viral portal vertex of bacteriophage lambda.
J.Virol., 98, 2024
8XOU
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BU of 8xou by Molmil
Prohead portal vertex of bacteriophage lambda
Descriptor: Major capsid protein, Portal protein B
Authors:Wang, J.W, Gu, Z.W.
Deposit date:2024-01-02
Release date:2024-04-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (5.58 Å)
Cite:Structural morphing in the viral portal vertex of bacteriophage lambda.
J.Virol., 98, 2024
8XOT
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BU of 8xot by Molmil
Prohead portal of bacteriophage lambda
Descriptor: Portal protein B
Authors:Wang, J.W, Gu, Z.W.
Deposit date:2024-01-02
Release date:2024-04-10
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Structural morphing in the viral portal vertex of bacteriophage lambda.
J.Virol., 98, 2024
8XNG
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BU of 8xng by Molmil
Cryo-EM structure of OSCA1.2-liposome-inside-out closed state
Descriptor: Calcium permeable stress-gated cation channel 1
Authors:Zhang, Y, Han, Y.
Deposit date:2023-12-29
Release date:2024-04-10
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8XN8
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BU of 8xn8 by Molmil
The Crystal Structure of SRC from Biortus.
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ...
Authors:Wang, F, Cheng, W, Yuan, Z, Lin, D, Bao, C.
Deposit date:2023-12-29
Release date:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Crystal Structure of SRC from Biortus.
To Be Published
8XN7
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BU of 8xn7 by Molmil
Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with compound 9f
Descriptor: 5-amino-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-8-(2-(trifluoromethyl)benzyl)pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase kinase kinase kinase 1
Authors:Huang, W.X, Liu, R, Ding, K.
Deposit date:2023-12-29
Release date:2024-04-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors.
Eur.J.Med.Chem., 269, 2024
8XMO
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BU of 8xmo by Molmil
Voltage-gated sodium channel Nav1.7 variant M4
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, N, Li, Z, Wu, Q, Huang, G.
Deposit date:2023-12-27
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Dissection of the structure-function relationship of Na v channels.
Proc.Natl.Acad.Sci.USA, 121, 2024
8XMN
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BU of 8xmn by Molmil
Voltage-gated sodium channel Nav1.7 variant M2
Descriptor: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Yan, N, Li, Z, Wu, Q, Huang, G.
Deposit date:2023-12-27
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Dissection of the structure-function relationship of Na v channels.
Proc.Natl.Acad.Sci.USA, 121, 2024
8XMM
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BU of 8xmm by Molmil
Voltage-gated sodium channel Nav1.7 variant M9
Descriptor: (2S,3R,4E)-2-(acetylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ...
Authors:Yan, N, Li, Z, Wu, Q, Huang, G.
Deposit date:2023-12-27
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Dissection of the structure-function relationship of Na v channels.
Proc.Natl.Acad.Sci.USA, 121, 2024
8XM7
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BU of 8xm7 by Molmil
Cryo-EM structure of the RhoG/DOCK5/ELMO1/Rac1 complex: RhoG/DOCK5/ELMO1 focused map
Descriptor: Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Kukimoto-Niino, M, Katsura, K, Ishizuka-Katsura, Y, Mishima-Tsumagari, C, Yonemochi, M, Inoue, M, Nakagawa, R, Kaushik, R, Zhang, K.Y.J, Shirouzu, M.
Deposit date:2023-12-27
Release date:2024-06-26
Method:ELECTRON MICROSCOPY (4.91 Å)
Cite:RhoG facilitates a conformational transition in the guanine nucleotide exchange factor complex DOCK5/ELMO1 to an open state.
J.Biol.Chem., 2024
8XM1
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BU of 8xm1 by Molmil
Phytase mutant APPAmut4
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Phytase
Authors:Tu, T, Wang, Q.
Deposit date:2023-12-27
Release date:2024-07-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The mutant crystal structure of phytase APPAmut4 from Yersinia intermedia
To Be Published
8XLQ
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BU of 8xlq by Molmil
FGFR4 kinase domain with a dual-warhead covalent inhibitor CXF-007
Descriptor: CXF007, Fibroblast growth factor receptor 4, SULFATE ION
Authors:Chen, X.J, Chen, Y.H.
Deposit date:2023-12-26
Release date:2024-03-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4.
Eur.J.Med.Chem., 268, 2024
8XLO
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BU of 8xlo by Molmil
FGFR1 kinase domain with a dual-warhead covalent inhibitor CXF-007
Descriptor: CXF007, Fibroblast growth factor receptor 1, SULFATE ION
Authors:Chen, X.J, Chen, Y.H.
Deposit date:2023-12-26
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4.
Eur.J.Med.Chem., 268, 2024

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PDB entries from 2024-07-10

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