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4B09
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BU of 4b09 by Molmil
Structure of unphosphorylated BaeR dimer
Descriptor: HEXATANTALUM DODECABROMIDE, TRANSCRIPTIONAL REGULATORY PROTEIN BAER
Authors:Choudhury, H, Beis, K.
Deposit date:2012-06-29
Release date:2013-07-10
Last modified:2013-09-25
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The Dimeric Form of the Unphosphorylated Response Regulator Baer.
Protein Sci., 22, 2013
7VE6
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BU of 7ve6 by Molmil
N-terminal domain of VraR
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator protein VraR
Authors:Kumar, J.V, Chen, C, Hsu, C.H.
Deposit date:2021-09-08
Release date:2022-05-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural insights into DNA binding domain of vancomycin-resistance-associated response regulator in complex with its promoter DNA from Staphylococcus aureus.
Protein Sci., 31, 2022
8JO2
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BU of 8jo2 by Molmil
Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA
Descriptor: DNA (65-MER), DNA-binding transcriptional regulator BasR, DNA-directed RNA polymerase subunit alpha, ...
Authors:Lou, Y.-C, Huang, H.-Y, Chen, C, Wu, K.-P.
Deposit date:2023-06-06
Release date:2023-08-30
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:Structural basis of transcriptional activation by the OmpR/PhoB-family response regulator PmrA.
Nucleic Acids Res., 51, 2023
5O8Y
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BU of 5o8y by Molmil
Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator.
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, SULFATE ION, Transcriptional regulatory protein RcsB
Authors:Casino, P, Marina, A, Miguel-Romero, L, Huesa, J.
Deposit date:2017-06-14
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator.
Nucleic Acids Res., 46, 2018
6LGQ
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BU of 6lgq by Molmil
The crystal complex structure of histidine kinase and response regulator
Descriptor: DNA-binding response regulator, Histidine kinase KdpD
Authors:Ming, Q.X.
Deposit date:2019-12-05
Release date:2020-12-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal complex structure of histidine kinase and response regulator
To Be Published
7SSI
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BU of 7ssi by Molmil
CRYSTAL STRUCTURE OF THE DESK:DESR-Q10A COMPLEX IN THE PHOSPHOTRANSFER STATE
Descriptor: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Sensor histidine kinase DesK, ...
Authors:Trajtenberg, F, Buschiazzo, A.
Deposit date:2021-11-11
Release date:2022-11-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis.
Sci.Signal., 16, 2023
7SSJ
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BU of 7ssj by Molmil
Crystal structure of the DesK-DesR complex in the phosphatase state
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Trajtenberg, F, Buschiazzo, A.
Deposit date:2021-11-11
Release date:2022-11-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:An allosteric switch ensures efficient unidirectional information transmission by the histidine kinase DesK from Bacillus subtilis.
Sci.Signal., 16, 2023
5O8Z
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BU of 5o8z by Molmil
Conformational dynamism for DNA interaction in Salmonella typhimurium RcsB response regulator.
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Transcriptional regulatory protein RcsB
Authors:Casino, P, Marina, A, Miguel-Romero, L, Huesa, J.
Deposit date:2017-06-14
Release date:2017-11-15
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator.
Nucleic Acids Res., 46, 2018
8AVW
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BU of 8avw by Molmil
Cryo-EM structure of DrBphP in Pr state
Descriptor: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome,Response regulator
Authors:Wahlgren, W.Y, Takala, H, Westenhoff, S.
Deposit date:2022-08-27
Release date:2022-12-21
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.62 Å)
Cite:Structural mechanism of signal transduction in a phytochrome histidine kinase.
Nat Commun, 13, 2022
8AVV
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BU of 8avv by Molmil
Cryo-EM structure of DrBphP photosensory module in Pr state
Descriptor: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome,Response regulator
Authors:Wahlgren, W.Y, Takala, H, Westenhoff, S.
Deposit date:2022-08-27
Release date:2022-12-21
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural mechanism of signal transduction in a phytochrome histidine kinase.
Nat Commun, 13, 2022
8AVX
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BU of 8avx by Molmil
Cryo-EM structure of DrBphP in Pfr state
Descriptor: BILIVERDINE IX ALPHA, Bacteriophytochrome,Response regulator
Authors:Wahlgren, W.Y, Takala, H, Westenhoff, S.
Deposit date:2022-08-27
Release date:2022-12-21
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural mechanism of signal transduction in a phytochrome histidine kinase.
Nat Commun, 13, 2022
6ZXM
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BU of 6zxm by Molmil
Diguanylate cyclase DgcR in complex with c-di-GMP
Descriptor: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, Putative GGDEF/response regulator receiver domain protein
Authors:Teixeira, R.D, Schirmer, T.
Deposit date:2020-07-29
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase.
Nat Commun, 12, 2021
6ZXC
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BU of 6zxc by Molmil
Diguanylate cyclase DgcR (I-site mutant) in activated state
Descriptor: 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative GGDEF/response regulator receiver domain protein
Authors:Teixeira, R.D, Schirmer, T.
Deposit date:2020-07-29
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase.
Nat Commun, 12, 2021
6ZXB
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BU of 6zxb by Molmil
Diguanylate cyclase DgcR (I-site mutant) in native state
Descriptor: 1,2-ETHANEDIOL, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Teixeira, R.D, Schirmer, T.
Deposit date:2020-07-29
Release date:2021-03-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Activation mechanism of a small prototypic Rec-GGDEF diguanylate cyclase.
Nat Commun, 12, 2021
4YN8
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BU of 4yn8 by Molmil
Crystal Structure of Response Regulator ChrA in Heme-Sensing Two Component System
Descriptor: MAGNESIUM ION, Response regulator ChrA, SULFATE ION
Authors:Doi, A, Nakamura, H, Shiro, Y, Sugimoto, H.
Deposit date:2015-03-09
Release date:2015-08-19
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the response regulator ChrA in the haem-sensing two-component system of Corynebacterium diphtheriae.
Acta Crystallogr.,Sect.F, 71, 2015
6AZR
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BU of 6azr by Molmil
Crystal structure of the T264A HK853cp-BeF3-RR468 complex
Descriptor: Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Rose, J, Zhou, P.
Deposit date:2017-09-11
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.628 Å)
Cite:A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases.
Nat Commun, 8, 2017
7P8E
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BU of 7p8e by Molmil
Crystal structure of the Receiver domain of M. truncatula cytokinin receptor MtCRE1
Descriptor: CALCIUM ION, Receiver domain of histidine kinase
Authors:Tran, L.H, Urbanowicz, A, Jasinski, M, Jaskolski, M, Ruszkowski, M.
Deposit date:2021-07-21
Release date:2021-10-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:3D Domain Swapping Dimerization of the Receiver Domain of Cytokinin Receptor CRE1 From Arabidopsis thaliana and Medicago truncatula .
Front Plant Sci, 12, 2021
7ESG
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BU of 7esg by Molmil
Crystal structure of Haloarcula marismortui CheB with Glutathione S-transferase expression tag
Descriptor: Glutathione S-transferase,Protein-glutamate methylesterase/protein-glutamine glutaminase
Authors:Chen, K.L, Yang, C.S.
Deposit date:2021-05-10
Release date:2022-07-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal structure of Haloarcula marismortui CheB with Glutathione S-transferase expression tag
To Be Published
4ZMS
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BU of 4zms by Molmil
Structure of the full-length response regulator spr1814 in complex with a phosphate analogue and B3C
Descriptor: 5-amino-2,4,6-tribromobenzene-1,3-diyl dihydroperoxide, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Chi, Y.M, Park, A.
Deposit date:2015-05-04
Release date:2016-04-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural characterization of the full-length response regulator spr1814 in complex with a phosphate analogue reveals a novel conformational plasticity of the linker region
Biochem.Biophys.Res.Commun., 473, 2016
7E1B
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BU of 7e1b by Molmil
Crystal structure of VbrR-DNA complex
Descriptor: DNA (26-MER), DNA-binding response regulator
Authors:Hong, S, Zhang, X, Zhang, P.
Deposit date:2021-02-01
Release date:2022-02-09
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (4.587 Å)
Cite:Structural basis of phosphorylation-induced activation of the response regulator VbrR.
Acta Biochim.Biophys.Sin., 2023
4ZMR
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BU of 4zmr by Molmil
Structural characterization of the full-length response regulator spr1814 in complex with a phosphate analogue reveals a novel conformational plasticity of the linker region
Descriptor: BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Response regulator
Authors:Chi, Y.M, Park, A.
Deposit date:2015-05-04
Release date:2016-04-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural characterization of the full-length response regulator spr1814 in complex with a phosphate analogue reveals a novel conformational plasticity of the linker region
Biochem.Biophys.Res.Commun., 473, 2016
5ED4
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BU of 5ed4 by Molmil
Structure of a PhoP-DNA complex
Descriptor: 1,2-ETHANEDIOL, CACODYLATE ION, CALCIUM ION, ...
Authors:Wang, S.
Deposit date:2015-10-20
Release date:2016-04-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of DNA sequence recognition by the response regulator PhoP in Mycobacterium tuberculosis.
Sci Rep, 6, 2016
5F64
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BU of 5f64 by Molmil
Putative positive transcription regulator (sensor EvgS) from Shigella flexneri
Descriptor: Positive transcription regulator EvgA
Authors:Nocek, B, Osipiuk, J, Mulligan, R, Gu, M, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-12-05
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Putative positive transcription regulator (sensor EvgS) from Shigella flexneri.
to be published
7PV7
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BU of 7pv7 by Molmil
Crystal structure of dimeric Porphyromonas gingivalis PorX, a type 9 secretion system response regulator.
Descriptor: BERYLLIUM TRIFLUORIDE ION, FORMIC ACID, GLYCEROL, ...
Authors:Schmitz, C.A, Madej, M, Potempa, J, Sola, M.
Deposit date:2021-10-01
Release date:2022-12-14
Last modified:2022-12-28
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Response regulator PorX coordinates oligonucleotide signalling and gene expression to control the secretion of virulence factors.
Nucleic Acids Res., 50, 2022
7PVA
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BU of 7pva by Molmil
1.9 Angstrom crystal structure of dimeric PorX, co-crystallized in the presence of zinc
Descriptor: BERYLLIUM TRIFLUORIDE ION, CHLORIDE ION, FORMIC ACID, ...
Authors:Schmitz, C.A, Madej, M, Potempa, J, Sola, M.
Deposit date:2021-10-01
Release date:2022-12-14
Last modified:2022-12-28
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Response regulator PorX coordinates oligonucleotide signalling and gene expression to control the secretion of virulence factors.
Nucleic Acids Res., 50, 2022

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